| Synonyms |
DMCT
demeclocycline
demeclocyclinum
7-chloro-6-demethyltetracycline
[4S-(4alpha,4aalpha,5aalpha,6beta,12aalpha)]-7-chloro-4-(dimethylamino)1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-2-naphthacenecarboxamide
C21H21ClN2O8
demeclociclina
Demeclocycline
DMCTC
(4S,4aS,5aS,6S,12aS)-7-chloro-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
demethylchlortetracycline
6-demethyl-7-chlorotetracycline
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| DBSynonym |
demethylchlortetracyclin demeclocyclinum [inn-latin] demethylchlortetracyclinum 7-chloro-6-demethyltetracycline methylchlorotetracycline demeclocycline [usan:ban] dmct demethylchlorotetracycline demeclociclina [inn-spanish] tri-demethylchlortetracycline 6-demethylchlorotetracycline demethylchlortetracycline 6-demethyl-7-chlorotetracycline
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| Definition |
Tetracycline which lacks the methyl substituent at position 7 and in which the hydrogen para- to the phenolic hydroxy group is substituted by chlorine. Like tetracycline, it is an antibiotic, but being excreted more slowly, effective blood levels are maintained for longer. It is used (mainly as the hydrochloride) for the treatment of Lyme disease, acne and bronchitis, as well as for hyponatraemia (low blood sodium concentration) due to the syndrome of inappropriate antidiuretic hormone (SIADH) where fluid restriction alone has been ineffective.
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| InChI |
InChI=1S/C21H21ClN2O8/c1-24(2)14-7-5-6-10(16(27)12-9(25)4-3-8(22)11(12)15(6)26)18(29)21(7,32)19(30)13(17(14)28)20(23)31/h3-4,6-7,14-15,25-26,28-29,32H,5H2,1-2H3,(H2,23,31)/t6-,7-,14-,15-,21-/m0/s1
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| Synonym |
DMCT demeclocycline demeclocyclinum 7-chloro-6-demethyltetracycline [4S-(4alpha,4aalpha,5aalpha,6beta,12aalpha)]-7-chloro-4-(dimethylamino)1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-2-naphthacenecarboxamide C21H21ClN2O8 demeclociclina Demeclocycline DMCTC (4S,4aS,5aS,6S,12aS)-7-chloro-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide demethylchlortetracycline 6-demethyl-7-chlorotetracycline
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