The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

dexamethasone

Synonyms

1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone

dexametasona

(1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one

dexamethasone

dexamethasonum

9alpha-Fluoro-16alpha-methylprednisolone

Dexamethasone

Decadron

16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol

C22H29FO5

9-fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione

ID

http://purl.obolibrary.org/obo/CHEBI_41879

activates

http://purl.obolibrary.org/obo/dinto_0764

http://purl.obolibrary.org/obo/dinto_0955

http://purl.obolibrary.org/obo/dinto_2874

AHFScode

52:08.08

68:04.00

altId

CHEBI:4461

CHEBI:41873

ATCCode

S02BA06

C05AA09

S03BA01

H02AB02

R01AD03

D07AB19

A01AC02

S01CB01

D10AA03

D07XB05

S01BA01

CASRN

50-02-2

DBBrand

aeroseb-dex

deseronil

dectancyl

dexapolcort

hexadrol elixir

decalix

mediamethasone

dexasone

lokalison f

millicorten

visumetazone

turbinaire

dexafarma

auxiron

isopto-dex

dexinoral

dexone 0.75

decasone

dexone 1.5

dexamethasone intensol

decadron

calonat

corson

dexa-mamallet

superprednol

fortecortin

cortisumman

dexadeltone

dexaltin

dexa mamallet

azium

dexa-scheroson

loverine

posurdex

aphtasolon

decadron tablets, elixir

decacort

hexadrol

hexadrol tablets

gammacorten

bisu ds

aphthasolone

dexone 0.5

oradexon

fluormone

dexinolon

pet derm iii

dextelan

pet-derm iii

dexalona

deltafluorene

dexacortal

dexa-cortidelt

sk-dexamethasone

dexacort

dexamonozon

anaflogistico

decadron-la

sunia sol d

spoloven

dexa-cortisyl

dexa-sine

dexapos

decagel

dexonium

prednisolone f

deronil

mymethasone

dexone 4

hexadecadrol

corsone

decacortin

dexameth

mexidex

dexa

prednisolon f

iontodex

luxazone

dekacort

policort

dinormon

hl-dex

dexaprol

dezone

dergramin

adexone

fluorocort

aeroseb-d

desadrene

desameton

decaderm

maxidex

dexone

decaspray

ocu-trol

dexacortin

dexason

dex-ide

DBname

dexamethasone

DBSynonym

dexamethasonum [inn-latin]

desametasone

desamethasone

desametasone [dcit]

dexamethasone sodium phosphate

dexamethasone acetate

dexametasona [inn-spanish]

dexamethazone

fluormethylprednisolone

Definition

A fluorinated steroid that has formula C22H29FO5.

has effect

http://purl.obolibrary.org/obo/OAE_0000355

http://purl.obolibrary.org/obo/OAE_0001101

http://purl.obolibrary.org/obo/OAE_0000400

http://purl.obolibrary.org/obo/OAE_0000390

http://purl.obolibrary.org/obo/OAE_0000401

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0001345

http://purl.obolibrary.org/obo/OAE_0000218

http://purl.obolibrary.org/obo/OAE_0000577

http://purl.obolibrary.org/obo/OAE_0001035

http://purl.obolibrary.org/obo/OAE_0000333

http://purl.obolibrary.org/obo/OAE_0001070

http://purl.obolibrary.org/obo/OAE_0001280

http://purl.obolibrary.org/obo/OAE_0001291

http://purl.obolibrary.org/obo/OAE_0001449

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000197

http://purl.obolibrary.org/obo/OAE_0000489

http://purl.obolibrary.org/obo/OAE_0000789

http://purl.obolibrary.org/obo/OAE_0000418

http://purl.obolibrary.org/obo/OAE_0001234

http://purl.obolibrary.org/obo/OAE_0000894

http://purl.obolibrary.org/obo/OAE_0000501

http://purl.obolibrary.org/obo/OAE_0000780

http://purl.obolibrary.org/obo/OAE_0000306

http://purl.obolibrary.org/obo/OAE_0001468

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0000630

http://purl.obolibrary.org/obo/OAE_0000250

http://purl.obolibrary.org/obo/OAE_0001744

http://purl.obolibrary.org/obo/OAE_0002206

http://purl.obolibrary.org/obo/OAE_0001515

http://purl.obolibrary.org/obo/OAE_0000470

http://purl.obolibrary.org/obo/OAE_0000838

http://purl.obolibrary.org/obo/OAE_0000469

http://purl.obolibrary.org/obo/OAE_0000785

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0001276

http://purl.obolibrary.org/obo/OAE_0000195

http://purl.obolibrary.org/obo/OAE_0000403

http://purl.obolibrary.org/obo/OAE_0000565

http://purl.obolibrary.org/obo/OAE_0000460

http://purl.obolibrary.org/obo/OAE_0000243

http://purl.obolibrary.org/obo/OAE_0001336

http://purl.obolibrary.org/obo/OAE_0000454

http://purl.obolibrary.org/obo/OAE_0000038

http://purl.obolibrary.org/obo/OAE_0001397

http://purl.obolibrary.org/obo/OAE_0001073

http://purl.obolibrary.org/obo/OAE_0000303

http://purl.obolibrary.org/obo/OAE_0001259

http://purl.obolibrary.org/obo/OAE_0000660

http://purl.obolibrary.org/obo/OAE_0000525

http://purl.obolibrary.org/obo/OAE_0000561

http://purl.obolibrary.org/obo/OAE_0000779

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0001529

http://purl.obolibrary.org/obo/OAE_0000373

has pharmacological target

http://purl.obolibrary.org/obo/dinto_2874

has role

http://purl.obolibrary.org/obo/CHEBI_50919

http://purl.obolibrary.org/obo/CHEBI_35705

http://purl.obolibrary.org/obo/CHEBI_35610

http://purl.obolibrary.org/obo/CHEBI_35472

http://purl.obolibrary.org/obo/CHEBI_37962

InChI

InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1

InChIKey

InChIKey=UREBDLICKHMUKA-CXSFZGCWSA-N

induces

http://purl.obolibrary.org/obo/dinto_2058

http://purl.obolibrary.org/obo/dinto_1956

http://purl.obolibrary.org/obo/dinto_2990

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_0456

http://purl.obolibrary.org/obo/dinto_0762

http://purl.obolibrary.org/obo/dinto_2496

http://purl.obolibrary.org/obo/dinto_0269

http://purl.obolibrary.org/obo/dinto_0285

http://purl.obolibrary.org/obo/dinto_0291

http://purl.obolibrary.org/obo/dinto_0293

http://purl.obolibrary.org/obo/dinto_2993

http://purl.obolibrary.org/obo/dinto_0887

http://purl.obolibrary.org/obo/dinto_1440

http://purl.obolibrary.org/obo/dinto_3489

http://purl.obolibrary.org/obo/dinto_0465

http://purl.obolibrary.org/obo/dinto_3102

http://purl.obolibrary.org/obo/dinto_1221

inhibits

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_0883

http://purl.obolibrary.org/obo/dinto_1987

http://purl.obolibrary.org/obo/dinto_0266

http://purl.obolibrary.org/obo/dinto_0269

http://purl.obolibrary.org/obo/dinto_1440

http://purl.obolibrary.org/obo/dinto_1559

is metabolised by

http://purl.obolibrary.org/obo/dinto_1956

http://purl.obolibrary.org/obo/dinto_2990

http://purl.obolibrary.org/obo/dinto_0901

is transported by

http://purl.obolibrary.org/obo/dinto_1440

label

dexamethasone

may interact with

http://purl.obolibrary.org/obo/CHEBI_9073

http://purl.obolibrary.org/obo/dinto_DB01346

http://purl.obolibrary.org/obo/dinto_DB01397

http://purl.obolibrary.org/obo/dinto_DB00237

http://purl.obolibrary.org/obo/CHEBI_10033

http://purl.obolibrary.org/obo/dinto_DB01399

http://purl.obolibrary.org/obo/dinto_DB01320

http://purl.obolibrary.org/obo/dinto_DB00312

http://purl.obolibrary.org/obo/CHEBI_4513

http://purl.obolibrary.org/obo/CHEBI_28077

http://purl.obolibrary.org/obo/CHEBI_251408

http://purl.obolibrary.org/obo/dinto_DB01341

http://purl.obolibrary.org/obo/CHEBI_32250

http://purl.obolibrary.org/obo/CHEBI_38940

http://purl.obolibrary.org/obo/CHEBI_70735

http://purl.obolibrary.org/obo/dinto_DB00794

http://purl.obolibrary.org/obo/CHEBI_6758

http://purl.obolibrary.org/obo/dinto_DB08864

http://purl.obolibrary.org/obo/dinto_DB08866

http://purl.obolibrary.org/obo/dinto_DB00382

http://purl.obolibrary.org/obo/dinto_DB00976

http://purl.obolibrary.org/obo/CHEBI_9513

http://purl.obolibrary.org/obo/CHEBI_70746

http://purl.obolibrary.org/obo/dinto_DB01122

http://purl.obolibrary.org/obo/dinto_DB01353

http://purl.obolibrary.org/obo/CHEBI_7514

http://purl.obolibrary.org/obo/dinto_DB01355

http://purl.obolibrary.org/obo/dinto_DB06287

http://purl.obolibrary.org/obo/dinto_DB01352

http://purl.obolibrary.org/obo/CHEBI_133809

http://purl.obolibrary.org/obo/CHEBI_102524

http://purl.obolibrary.org/obo/dinto_DB01354

http://purl.obolibrary.org/obo/dinto_DB00306

http://purl.obolibrary.org/obo/CHEBI_15365

http://purl.obolibrary.org/obo/CHEBI_9654

http://purl.obolibrary.org/obo/dinto_DB00072

http://purl.obolibrary.org/obo/dinto_DB00545

http://purl.obolibrary.org/obo/CHEBI_499361

http://purl.obolibrary.org/obo/dinto_DB00532

http://purl.obolibrary.org/obo/CHEBI_2654

http://purl.obolibrary.org/obo/dinto_DB01351

http://purl.obolibrary.org/obo/CHEBI_47657

http://purl.obolibrary.org/obo/dinto_DB00582

http://purl.obolibrary.org/obo/CHEBI_49960

http://purl.obolibrary.org/obo/CHEBI_53766

http://purl.obolibrary.org/obo/CHEBI_8069

http://purl.obolibrary.org/obo/CHEBI_45783

http://purl.obolibrary.org/obo/CHEBI_102216

http://purl.obolibrary.org/obo/CHEBI_8107

http://purl.obolibrary.org/obo/CHEBI_9939

http://purl.obolibrary.org/obo/CHEBI_4888

http://purl.obolibrary.org/obo/CHEBI_6933

prefixIRI

obo2:CHEBI_41879

prefLabel

dexamethasone

related with

http://purl.obolibrary.org/obo/dinto_0076

SMILES

[H][C@@]12C[C@@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C

Synonym

1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone

dexametasona

(1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one

dexamethasone

dexamethasonum

9alpha-Fluoro-16alpha-methylprednisolone

Dexamethasone

Decadron

16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol

C22H29FO5

9-fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione

xref

ChEMBL:465281

ChemSpider:5541

RxList:http://www.rxlist.com/cgi/generic/dexameth.htm

PubChem Compound:5743

IUPHAR:2768

Patent:GB869511

PubChem Substance:46508930

BindingDB:18207

PDB:DEX

Beilstein:2066652

National Drug Code Directory:0703-3524-03

Patent:DE1113690

Patent:US3007923

KEGG DRUG:D00292

ChEBI:41879

Wikipedia:http://en.wikipedia.org/wiki/Dexamethasone

Guide To Pharmacology:2768

Wikipedia:Dexamethasone

PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/dec1118.shtml

Drugs.com:http://www.drugs.com/cdi/dexamethasone-drops.html

Drugs Product Database (DPD):664227

DrugBank:DB01234

PharmGKB:PA449247

CASRN:50-02-2

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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