The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

tamoxifen

Synonyms

2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine

Diemon

tamoxifen

Crisafeno

trans-Tamoxifen

tamoxifene

Apo-Tamox

tamoxifeno

(Z)-2-(para-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylamine

tamoxifenum

(Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamine

Tamoxifen

1-para-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene

1-p-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene

C26H29NO

(2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethyl)dimethylamine

ID

http://purl.obolibrary.org/obo/CHEBI_41774

activates

http://purl.obolibrary.org/obo/dinto_2830

http://purl.obolibrary.org/obo/dinto_2827

AHFScode

10:00.00

altId

CHEBI:41767

CHEBI:9396

ATCCode

L02BA01

blocks

http://purl.obolibrary.org/obo/dinto_2830

http://purl.obolibrary.org/obo/dinto_2827

CASRN

10540-29-1

DBBrand

valodex

tamizam

novo-tamoxifen

tamoxasta

tamoxen

tamone

nolvadex

nolvadex-d

noltam

oncomox

pms-tamoxifen

retaxim

diemon

nourytam

zemide

soltamox

crisafeno

tamofen

istubol

citofen

gen-tamoxifen

DBname

tamoxifen

DBSalt

tamoxifen citrate

DBSynonym

tamoxifen citras

nolvadex

ici-46474

Definition

A stilbenoid that has formula C26H29NO.

has effect

http://purl.obolibrary.org/obo/OAE_0000599

http://purl.obolibrary.org/obo/OAE_0001044

http://purl.obolibrary.org/obo/OAE_0000505

http://purl.obolibrary.org/obo/OAE_0000401

http://purl.obolibrary.org/obo/OAE_0000185

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0000643

http://purl.obolibrary.org/obo/OAE_0000567

http://purl.obolibrary.org/obo/OAE_0001153

http://purl.obolibrary.org/obo/OAE_0000577

http://purl.obolibrary.org/obo/OAE_0000462

http://purl.obolibrary.org/obo/OAE_0001129

http://purl.obolibrary.org/obo/OAE_0000449

http://purl.obolibrary.org/obo/OAE_0001448

http://purl.obolibrary.org/obo/OAE_0000300

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000533

http://purl.obolibrary.org/obo/OAE_0001052

http://purl.obolibrary.org/obo/OAE_0000534

http://purl.obolibrary.org/obo/OAE_0000385

http://purl.obolibrary.org/obo/OAE_0001510

http://purl.obolibrary.org/obo/OAE_0000406

http://purl.obolibrary.org/obo/OAE_0000050

http://purl.obolibrary.org/obo/OAE_0000789

http://purl.obolibrary.org/obo/OAE_0000396

http://purl.obolibrary.org/obo/OAE_0000418

http://purl.obolibrary.org/obo/OAE_0001340

http://purl.obolibrary.org/obo/OAE_0000766

http://purl.obolibrary.org/obo/OAE_0000604

http://purl.obolibrary.org/obo/OAE_0001200

http://purl.obolibrary.org/obo/OAE_0000596

http://purl.obolibrary.org/obo/OAE_0001595

http://purl.obolibrary.org/obo/OAE_0000811

http://purl.obolibrary.org/obo/OAE_0000375

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0001744

http://purl.obolibrary.org/obo/OAE_0002206

http://purl.obolibrary.org/obo/OAE_0001515

http://purl.obolibrary.org/obo/OAE_0000943

http://purl.obolibrary.org/obo/OAE_0000506

http://purl.obolibrary.org/obo/OAE_0001505

http://purl.obolibrary.org/obo/OAE_0000493

http://purl.obolibrary.org/obo/OAE_0000861

http://purl.obolibrary.org/obo/OAE_0000343

http://purl.obolibrary.org/obo/OAE_0000319

http://purl.obolibrary.org/obo/OAE_0000275

http://purl.obolibrary.org/obo/OAE_0001217

http://purl.obolibrary.org/obo/OAE_0000194

http://purl.obolibrary.org/obo/OAE_0000084

http://purl.obolibrary.org/obo/OAE_0001463

http://purl.obolibrary.org/obo/OAE_0000487

http://purl.obolibrary.org/obo/OAE_0000195

http://purl.obolibrary.org/obo/OAE_0000921

http://purl.obolibrary.org/obo/OAE_0000382

http://purl.obolibrary.org/obo/OAE_0000403

http://purl.obolibrary.org/obo/OAE_0000414

http://purl.obolibrary.org/obo/OAE_0000565

http://purl.obolibrary.org/obo/OAE_0000402

http://purl.obolibrary.org/obo/OAE_0000034

http://purl.obolibrary.org/obo/OAE_0000021

http://purl.obolibrary.org/obo/OAE_0000415

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000310

http://purl.obolibrary.org/obo/OAE_0000645

http://purl.obolibrary.org/obo/OAE_0000453

http://purl.obolibrary.org/obo/OAE_0000647

http://purl.obolibrary.org/obo/OAE_0000879

http://purl.obolibrary.org/obo/OAE_0001155

http://purl.obolibrary.org/obo/OAE_0000038

http://purl.obolibrary.org/obo/OAE_0000498

http://purl.obolibrary.org/obo/OAE_0000660

http://purl.obolibrary.org/obo/OAE_0000602

http://purl.obolibrary.org/obo/OAE_0000210

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000584

http://purl.obolibrary.org/obo/OAE_0002122

http://purl.obolibrary.org/obo/OAE_0000455

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0000618

http://purl.obolibrary.org/obo/OAE_0001529

http://purl.obolibrary.org/obo/OAE_0000373

has pharmacological target

http://purl.obolibrary.org/obo/dinto_2830

http://purl.obolibrary.org/obo/dinto_2827

has role

http://purl.obolibrary.org/obo/CHEBI_50739

http://purl.obolibrary.org/obo/CHEBI_35610

http://purl.obolibrary.org/obo/CHEBI_50646

http://purl.obolibrary.org/obo/CHEBI_48422

http://purl.obolibrary.org/obo/CHEBI_37700

http://purl.obolibrary.org/obo/CHEBI_50792

http://purl.obolibrary.org/obo/CHEBI_50837

InChI

InChI=1S/C26H29NO/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3/h5-18H,4,19-20H2,1-3H3/b26-25-

InChIKey

InChIKey=NKANXQFJJICGDU-QPLCGJKRSA-N

induces

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_1440

inhibits

http://purl.obolibrary.org/obo/dinto_2058

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_0285

http://purl.obolibrary.org/obo/dinto_2993

http://purl.obolibrary.org/obo/dinto_1440

http://purl.obolibrary.org/obo/dinto_3489

http://purl.obolibrary.org/obo/dinto_0465

http://purl.obolibrary.org/obo/dinto_3102

http://purl.obolibrary.org/obo/dinto_1221

http://purl.obolibrary.org/obo/dinto_0470

is metabolised by

http://purl.obolibrary.org/obo/dinto_2058

http://purl.obolibrary.org/obo/dinto_1956

http://purl.obolibrary.org/obo/dinto_2990

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_2496

http://purl.obolibrary.org/obo/dinto_0269

http://purl.obolibrary.org/obo/dinto_0285

http://purl.obolibrary.org/obo/dinto_0291

http://purl.obolibrary.org/obo/dinto_0293

http://purl.obolibrary.org/obo/dinto_2993

http://purl.obolibrary.org/obo/dinto_0270

http://purl.obolibrary.org/obo/dinto_3549

http://purl.obolibrary.org/obo/dinto_2045

http://purl.obolibrary.org/obo/dinto_0465

http://purl.obolibrary.org/obo/dinto_2651

http://purl.obolibrary.org/obo/dinto_2048

is transported by

http://purl.obolibrary.org/obo/dinto_0883

http://purl.obolibrary.org/obo/dinto_0887

http://purl.obolibrary.org/obo/dinto_1440

label

tamoxifen

prefixIRI

obo2:CHEBI_41774

prefLabel

tamoxifen

SMILES

CC\C(c1ccccc1)=C(/c1ccccc1)c1ccc(OCCN(C)C)cc1

CCC(=C(/C1=CC=CC=C1)C1=CC=C(OCCN(C)C)C=C1)C1=CC=CC=C1

Synonym

2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine

Diemon

tamoxifen

Crisafeno

trans-Tamoxifen

tamoxifene

Apo-Tamox

tamoxifeno

(Z)-2-(para-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylamine

tamoxifenum

(Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamine

Tamoxifen

1-para-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene

1-p-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene

C26H29NO

(2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethyl)dimethylamine

xref

CASRN:10540-29-1

RxList:http://www.rxlist.com/cgi/generic/tamox.htm

IUPHAR:1016

CiteXplore:14709804

CiteXplore:7688593

PDB:OHT

National Drug Code Directory:0378-0144-91

PharmGKB:PA451581

ChEBI:9396

Wikipedia:http://en.wikipedia.org/wiki/Tamoxifen

PubChem Substance:46505515

Beilstein:2062020

DrugBank:DB00675

Wikipedia:Tamoxifen

KEGG DRUG:D08559

ChemSpider:2015313

Drugs Product Database (DPD):2237460

Patent:BE678807

PubChem Compound:2733526

Patent:US4536516

ChEMBL:106968

Guide To Pharmacology:1016

HMDB:HMDB14813

KEGG COMPOUND:C07108

BindingDB:20607

CiteXplore:18348622

Patent:BE637389

Drugs.com:http://www.drugs.com/tamoxifen.html

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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Delete Mapping To Ontology Source
http://www.drugbank.ca/drugs/DB00675 FTC LOOM
http://purl.bioontology.org/ontology/NDDF/004826 NDDF LOOM
http://purl.bioontology.org/ontology/RXNORM/10324 RXNORM LOOM
http://purl.bioontology.org/ontology/RXNORM/10324 NLMVS LOOM
http://purl.bioontology.org/ontology/UATC/L02BA01 ATC LOOM
http://purl.bioontology.org/ontology/SNMI/C-781E0 SNMI LOOM
http://www.gamuts.net/entity#tamoxifen GAMUTS LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/75959001 SNOMEDCT LOOM
http://d-nb.info/gnd/4184395-2 FAST-TOPICAL LOOM
http://purl.bioontology.org/ontology/RCD/he4.. RCD LOOM
http://purl.bioontology.org/ontology/LNC/LA14344-8 LOINC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/373345002 SNOMEDCT LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000148024 ODAE LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D013629 RH-MESH LOOM
http://www.bioontology.org/pma.owl#PMA_1416 PMA LOOM
http://purl.jp/bio/4/id/200906003583642183 IOBC LOOM
http://purl.jp/bio/4/id/200906003583642183 IOBC LOOM
http://purl.obolibrary.org/obo/CHEBI_41774 ODNAE LOOM
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http://purl.obolibrary.org/obo/CHEBI_41774 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_41774 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_41774 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_41774 FYPO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_41774 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_41774 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_41774 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_41774 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_41774 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_41774 CCONT SAME_URI
http://purl.obolibrary.org/obo/CHEBI_41774 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_41774 FYPO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_41774 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_41774 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_41774 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_41774 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_41774 NBO LOOM
http://purl.obolibrary.org/obo/CHEBI_41774 NBO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_41774 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_41774 FYPO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_41774 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_41774 FYPO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_41774 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_41774 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_41774 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_41774 FYPO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_41774 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_41774 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_41774 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_41774 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_41774 HINO LOOM
http://purl.obolibrary.org/obo/CHEBI_41774 HINO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_41774 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_41774 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_41774 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_41774 FYPO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_41774 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_41774 NIFSTD SAME_URI
http://purl.bioontology.org/ontology/CSP/0119-1179 CRISP LOOM
http://purl.bioontology.org/ontology/MESH/D013629 MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.559.389.150.700.900 RH-MESH LOOM
http://www.co-ode.org/ontologies/galen#Tamoxifen GALEN LOOM
http://www.projecthalo.com/aura#Tamoxifen AURA LOOM
http://purl.bioontology.org/ontology/VANDF/4019939 VANDF LOOM
http://purl.bioontology.org/ontology/LNC/LP18484-3 LOINC LOOM
http://purl.org/obo/owl/CHEBI#CHEBI_41774 NPO LOOM
http://stirdf.jst.go.jp/id/200907076113483543 IOBC LOOM
http://www.ifomis.org/acgt/1.0#Tamoxifen ACGT-MO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62078 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62078 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62078 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62078 NCIT LOOM
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http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62078 NCIT LOOM
http://purl.bioontology.org/ontology/LNC/MTHU003102 LOINC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148024 NDFRT LOOM