The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

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Preferred Name	diflunisal
Synonyms	2-(hydroxy)-5-(2,4-difluorophenyl)benzoic acid 5-(2,4-difluorophenyl)-2-hydroxybenzoic acid Diflunisal 5-(2,4-difluorophenyl)salicylic acid 2',4'-difluoro-4-hydroxy-[1,1'-biphenyl]-3-carboxylic acid Dolobid 2',4'-difluoro-4-hydroxy-3-biphenylcarboxylic acid C13H8F2O3
ID	http://purl.obolibrary.org/obo/CHEBI_39669
AHFScode	28:08.04.92
altId	CHEBI:39656 CHEBI:4538
ATCCode	N02BA11
CASRN	22494-42-4
DBBrand	adomal dolobis fluniget fluodonil dolisal flovacil difludol dolobil dolobid flustar
DBname	diflunisal
Definition	An organofluorine compound comprising salicylic acid having a 2,4-difluorophenyl group at the 5-position.
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000449 http://purl.obolibrary.org/obo/OAE_0000453 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000902 http://purl.obolibrary.org/obo/OAE_0000391 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000406 http://purl.obolibrary.org/obo/OAE_0001509 http://purl.obolibrary.org/obo/OAE_0000512 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000210 http://purl.obolibrary.org/obo/OAE_0000021 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000382 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000979 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0000608 http://purl.obolibrary.org/obo/OAE_0000770 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0001463 http://purl.obolibrary.org/obo/OAE_0000268 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0000086 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0000607 http://purl.obolibrary.org/obo/OAE_0000968 http://purl.obolibrary.org/obo/OAE_0000034 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000866 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000536 http://purl.obolibrary.org/obo/OAE_0001209 http://purl.obolibrary.org/obo/OAE_0000468 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000565 http://purl.obolibrary.org/obo/OAE_0000881 http://purl.obolibrary.org/obo/OAE_0000211 http://purl.obolibrary.org/obo/OAE_0001366 http://purl.obolibrary.org/obo/OAE_0001364 http://purl.obolibrary.org/obo/OAE_0000811
has pharmacological target	http://purl.obolibrary.org/obo/dinto_2116
has role	http://purl.obolibrary.org/obo/CHEBI_35475 http://purl.obolibrary.org/obo/CHEBI_35481
InChI	InChI=1S/C13H8F2O3/c14-8-2-3-9(11(15)6-8)7-1-4-12(16)10(5-7)13(17)18/h1-6,16H,(H,17,18)
InChIKey	InChIKey=HUPFGZXOMWLGNK-UHFFFAOYSA-N
inhibits	http://purl.obolibrary.org/obo/dinto_0938 http://purl.obolibrary.org/obo/dinto_0520 http://purl.obolibrary.org/obo/dinto_2116
is metabolised by	http://purl.obolibrary.org/obo/dinto_1848
label	diflunisal
may interact with	http://purl.obolibrary.org/obo/dinto_DB00519 http://purl.obolibrary.org/obo/CHEBI_9434 http://purl.obolibrary.org/obo/CHEBI_44185 http://purl.obolibrary.org/obo/CHEBI_49662 http://purl.obolibrary.org/obo/CHEBI_53766 http://purl.obolibrary.org/obo/dinto_DB00373 http://purl.obolibrary.org/obo/CHEBI_133809 http://purl.obolibrary.org/obo/CHEBI_59594 http://purl.obolibrary.org/obo/dinto_DB01356 http://purl.obolibrary.org/obo/CHEBI_50861 http://purl.obolibrary.org/obo/CHEBI_10033 http://purl.obolibrary.org/obo/CHEBI_71223 http://purl.obolibrary.org/obo/CHEBI_4513 http://purl.obolibrary.org/obo/CHEBI_68845 http://purl.obolibrary.org/obo/CHEBI_8426 http://purl.obolibrary.org/obo/dinto_DB01381 http://purl.obolibrary.org/obo/dinto_DB06210 http://purl.obolibrary.org/obo/CHEBI_2567
prefixIRI	obo2:CHEBI_39669
prefLabel	diflunisal
related with	http://purl.obolibrary.org/obo/dinto_1573 http://purl.obolibrary.org/obo/dinto_0217
SMILES	OC(=O)c1cc(ccc1O)-c1ccc(F)cc1F OC(=O)C1=C(O)C=CC(=C1)C1=C(F)C=C(F)C=C1
Synonym	2-(hydroxy)-5-(2,4-difluorophenyl)benzoic acid 5-(2,4-difluorophenyl)-2-hydroxybenzoic acid Diflunisal 5-(2,4-difluorophenyl)salicylic acid 2',4'-difluoro-4-hydroxy-[1,1'-biphenyl]-3-carboxylic acid Dolobid 2',4'-difluoro-4-hydroxy-3-biphenylcarboxylic acid C13H8F2O3
xref	ChEMBL:177652 PubChem Compound:3059 Reaxys:2654431 RxList:http://www.rxlist.com/cgi/generic3/diflunisal.htm PDB:FHI National Drug Code Directory:54868-3049-3 CASRN:22494-42-4 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/dol1145.shtml Wikipedia:http://en.wikipedia.org/wiki/Diflunisal Drugs Product Database (DPD):2058413 NIST Chemistry WebBook:22494-42-4 Wikipedia:Diflunisal ChemSpider:2951 Drugs.com:http://www.drugs.com/cdi/diflunisal.html KEGG COMPOUND:C01691 ChEBI:39669 KEGG DRUG:D00130 PharmGKB:PA449313 PubChem Substance:46507807 DrugBank:DB00861
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/CHEBI_39669	HOIP	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_39669	CHEBI	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_39669	PDRO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_39669	FIDEO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_39669	BERO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_39669	TXPO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_39669	BIOMODELS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_39669	DRON	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_39669	NIFSTD	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_39669	HOIP	LOOM
http://purl.obolibrary.org/obo/CHEBI_39669	CHEBI	LOOM
http://purl.obolibrary.org/obo/ARO_3007091	ARO	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#3933	OCHV	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146300	NDFRT	LOOM
http://purl.bioontology.org/ontology/SNMI/C-603A0	SNMI	LOOM
http://purl.jp/bio/4/id/200906029732375966	IOBC	LOOM
http://www.co-ode.org/ontologies/galen#Diflunisal	GALEN	LOOM
http://purl.obolibrary.org/obo/MESH_D004061	BERO	LOOM
http://stirdf.jst.go.jp/id/200907009895116235	IOBC	LOOM
http://purl.bioontology.org/ontology/NDDF/001599	NDDF	LOOM
http://purl.bioontology.org/ontology/RCD/x02MM	RCD	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.559.389.657.410.595.303	RH-MESH	LOOM
http://purl.obolibrary.org/obo/OMIT_0005331	OMIT	LOOM
http://purl.obolibrary.org/obo/CHEBI_39669	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_39669	FIDEO	LOOM
http://purl.obolibrary.org/obo/CHEBI_39669	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_39669	TXPO	LOOM
http://purl.obolibrary.org/obo/CHEBI_39669	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/CHEBI_39669	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_39669	NIFSTD	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47489	NCIT	LOOM
https://go.drugbank.com/drugs/DB00861	MDM	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016863	PMAPP-PMO	LOOM
http://purl.bioontology.org/ontology/MESH/D004061	MESH	LOOM
http://www.drugbank.ca/drugs/DB00861	FTC	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0012228	OCHV	LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000691337	PDQ	LOOM
http://purl.obolibrary.org/obo/NCIT_C47489	BERO	LOOM
http://purl.bioontology.org/ontology/ATC/N02BA11	ATC	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387116004	SNOMEDCT	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D004061	RH-MESH	LOOM
http://purl.bioontology.org/ontology/LNC/LP18552-7	LOINC	LOOM
http://purl.bioontology.org/ontology/RXNORM/3393	RXNORM	LOOM
http://purl.bioontology.org/ontology/VANDF/4017950	VANDF	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU004624	LOINC	LOOM