The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
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Preferred Name

rosuvastatin
Synonyms

(3R,5S,6E)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid

(3R,5S,6E)-7-{4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid

C22H28FN3O6S

(3R,5S,6E)-7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-(ethyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5-dihydroxy-6-heptenoic acid

(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid
ID

http://purl.obolibrary.org/obo/CHEBI_38545
AHFScode

24:06.08
ATCCode

C10AA07
CASRN

287714-41-4
DBBrand

cirantan

rosuvast

simestat

provisacor

crestor

astende

cresadex

rovartal

rosimol

sinlip

visacor

rosuvas

rosedex

rosustatin

vivacor

rosvel

razel

rosumed
DBname

rosuvastatin
DBSalt

rosuvastatin calcium
DBSynonym

zd-4522
Definition

A pyrimidine that has formula C22H28FN3O6S.
has effect

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000496

http://purl.obolibrary.org/obo/OAE_0000453

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0000630

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0000596

http://purl.obolibrary.org/obo/OAE_0000406

http://purl.obolibrary.org/obo/OAE_0000411

http://purl.obolibrary.org/obo/OAE_0000611

http://purl.obolibrary.org/obo/OAE_0000567

http://purl.obolibrary.org/obo/OAE_0000195

http://purl.obolibrary.org/obo/OAE_0000373

http://purl.obolibrary.org/obo/OAE_0000210

http://purl.obolibrary.org/obo/OAE_0000319

http://purl.obolibrary.org/obo/OAE_0000412

http://purl.obolibrary.org/obo/OAE_0001448

http://purl.obolibrary.org/obo/OAE_0000660

http://purl.obolibrary.org/obo/OAE_0001280

http://purl.obolibrary.org/obo/OAE_0000382

http://purl.obolibrary.org/obo/OAE_0001025

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0001378

http://purl.obolibrary.org/obo/OAE_0000310

http://purl.obolibrary.org/obo/OAE_0001365

http://purl.obolibrary.org/obo/OAE_0001026

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000375

http://purl.obolibrary.org/obo/OAE_0000300

http://purl.obolibrary.org/obo/OAE_0000386

http://purl.obolibrary.org/obo/OAE_0000498

http://purl.obolibrary.org/obo/OAE_0001295

http://purl.obolibrary.org/obo/OAE_0000400

http://purl.obolibrary.org/obo/OAE_0000584

http://purl.obolibrary.org/obo/OAE_0001129

http://purl.obolibrary.org/obo/OAE_0002206

http://purl.obolibrary.org/obo/OAE_0000613

http://purl.obolibrary.org/obo/OAE_0000414

http://purl.obolibrary.org/obo/OAE_0000469

http://purl.obolibrary.org/obo/OAE_0000525

http://purl.obolibrary.org/obo/OAE_0000968

http://purl.obolibrary.org/obo/OAE_0002122

http://purl.obolibrary.org/obo/OAE_0000460

http://purl.obolibrary.org/obo/OAE_0000343

http://purl.obolibrary.org/obo/OAE_0001403

http://purl.obolibrary.org/obo/OAE_0000405

http://purl.obolibrary.org/obo/OAE_0000536

http://purl.obolibrary.org/obo/OAE_0000647

http://purl.obolibrary.org/obo/OAE_0000385

http://purl.obolibrary.org/obo/OAE_0000468

http://purl.obolibrary.org/obo/OAE_0000602

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0000514

http://purl.obolibrary.org/obo/OAE_0001001

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0000462

http://purl.obolibrary.org/obo/OAE_0001364

http://purl.obolibrary.org/obo/OAE_0000402

http://purl.obolibrary.org/obo/OAE_0000350
has pharmacological target

http://purl.obolibrary.org/obo/dinto_4019
has role

http://purl.obolibrary.org/obo/CHEBI_35664
InChI

InChI=1S/C22H28FN3O6S/c1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32/h5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30)/b10-9+/t16-,17-/m1/s1
InChIKey

InChIKey=BPRHUIZQVSMCRT-VEUZHWNKSA-N
inhibits

http://purl.obolibrary.org/obo/dinto_2058

http://purl.obolibrary.org/obo/dinto_2990

http://purl.obolibrary.org/obo/dinto_4019

http://purl.obolibrary.org/obo/dinto_0901
is metabolised by

http://purl.obolibrary.org/obo/dinto_2058

http://purl.obolibrary.org/obo/dinto_0291

http://purl.obolibrary.org/obo/dinto_0901
is substrate of

http://purl.obolibrary.org/obo/dinto_0217
is transported by

http://purl.obolibrary.org/obo/dinto_0883

http://purl.obolibrary.org/obo/dinto_2019

http://purl.obolibrary.org/obo/dinto_3489

http://purl.obolibrary.org/obo/dinto_2828

http://purl.obolibrary.org/obo/dinto_0300
label

rosuvastatin
may interact with

http://purl.obolibrary.org/obo/CHEBI_5001

http://purl.obolibrary.org/obo/CHEBI_5296

http://purl.obolibrary.org/obo/CHEBI_4031

http://purl.obolibrary.org/obo/dinto_DB01394

http://purl.obolibrary.org/obo/dinto_DB01378

http://purl.obolibrary.org/obo/CHEBI_63628
prefixIRI

obo2:CHEBI_38545
prefLabel

rosuvastatin
related with

http://purl.obolibrary.org/obo/dinto_0893

http://purl.obolibrary.org/obo/dinto_1824

http://purl.obolibrary.org/obo/dinto_1987

http://purl.obolibrary.org/obo/dinto_1322
SMILES

CC(C)c1nc(nc(-c2ccc(F)cc2)c1\\C=C\\[C@@H](O)C[C@@H](O)CC(O)=O)N(C)S(C)(=O)=O

CC(C)C1=NC(=NC(C2=CC=C(F)C=C2)=C1\C=C\[C@@H](O)C[C@@H](O)CC(=O)O)N(C)S(C)(=O)=O
Synonym

(3R,5S,6E)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid

(3R,5S,6E)-7-{4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid

C22H28FN3O6S

(3R,5S,6E)-7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-(ethyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5-dihydroxy-6-heptenoic acid

(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid
xref

ChEBI:38545

Wikipedia:http://en.wikipedia.org/wiki/Rosuvastatin

Drugs.com:http://www.drugs.com/cdi/rosuvastatin.html

Drugs Product Database (DPD):2247163

Wikipedia:Rosuvastatin

PharmGKB:PA134308647

PDB:FBI

National Drug Code Directory:0310-0755-90

RxList:http://www.rxlist.com/cgi/generic/crestor.htm

DrugBank:DB01098

BindingDB:50215703

Beilstein:9670765

CASRN:287714-41-4

ChEMBL:518845
subClassOf

http://purl.obolibrary.org/obo/dinto_000055
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http://purl.obolibrary.org/obo/CHEBI_38545 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_38545 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_38545 PDRO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_38545 BAO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_38545 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_38545 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_38545 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_38545 NIFSTD SAME_URI
http://purl.obolibrary.org/obo/CHEBI_38545 DIDEO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_38545 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_38545 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_38545 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_38545 BAO LOOM
http://purl.obolibrary.org/obo/CHEBI_38545 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_38545 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_38545 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_38545 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_38545 DIDEO LOOM
http://www.drugbank.ca/drugs/DB01098 FTC LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66523 NCIT LOOM
http://purl.bioontology.org/ontology/RXNORM/301542 RXNORM LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#53588 OCHV LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148821 NDFRT LOOM
http://bmi.utah.edu/ontologies/hfontology/C0965129 HFO LOOM
http://scai.fraunhofer.de/AlzheimerOntology#rosuvastatin ADO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C422923 RH-MESH LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02127 MIO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/700067006 SNOMEDCT LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000148821 OCVDAE LOOM
https://go.drugbank.com/drugs/DB01098 MDM LOOM
http://purl.obolibrary.org/obo/NCIT_C66523 BERO LOOM
http://purl.bioontology.org/ontology/ATC/C10AA07 ATC LOOM
http://purl.bioontology.org/ontology/NDDF/009902 NDDF LOOM
http://purl.bioontology.org/ontology/LNC/LP171638-2 LOINC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0965129 OCHV LOOM
http://purl.bioontology.org/ontology/VANDF/4021405 VANDF LOOM