loading...| Preferred Name |
chlorothiazide |
|
| Synonyms |
chlorothiazide Chlorothiazide 6-chloro-1,1-dioxo-4H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide chlorothiazidum 6-Chloro-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[1,2,4]thiadiazine-7-sulfonic acid amide C7H6ClN3O4S2 6-chloro-7-sulfamoyl-2H-1,2,4-benzothiadiazine 1,1-dioxide clorotiazida 6-chloro-4H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_3640 |
|
| altId |
CHEBI:162615 |
|
| ATCCode |
C03AA04 C03AA03 |
|
| CASRN |
58-94-6 |
|
| DBBrand |
saluric diuril chlotride clotride azide |
|
| DBname |
chlorothiazide |
|
| DBSynonym |
chlorthiazide chlorothiazid chlortiazid |
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| Definition |
4H-1,2,4-benzothiadiazine 1,1-dioxide in which the hydrogen at position is substituted by chlorine and that at position 7 is substituted by a sulfonamide group. A diuretic, it is used for treatment of oedema and hypertension. |
|
| has pharmacological target |
http://purl.obolibrary.org/obo/dinto_0512 http://purl.obolibrary.org/obo/dinto_0757 |
|
| has role | ||
| InChI |
InChI=1S/C7H6ClN3O4S2/c8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5/h1-3H,(H,10,11)(H2,9,12,13) |
|
| InChIKey |
InChIKey=JBMKAUGHUNFTOL-UHFFFAOYSA-N |
|
| inhibits |
http://purl.obolibrary.org/obo/dinto_0512 http://purl.obolibrary.org/obo/dinto_0757 http://purl.obolibrary.org/obo/dinto_1621 |
|
| label |
chlorothiazide |
|
| may interact with |
http://purl.obolibrary.org/obo/dinto_DB00519 http://purl.obolibrary.org/obo/CHEBI_4551 http://purl.obolibrary.org/obo/CHEBI_63631 http://purl.obolibrary.org/obo/dinto_DB01356 http://purl.obolibrary.org/obo/CHEBI_50861 http://purl.obolibrary.org/obo/dinto_DB00073 http://purl.obolibrary.org/obo/CHEBI_2636 http://purl.obolibrary.org/obo/CHEBI_59602 |
|
| prefixIRI |
obo2:CHEBI_3640 |
|
| prefLabel |
chlorothiazide |
|
| SMILES |
NS(=O)(=O)c1cc2c(NC=NS2(=O)=O)cc1Cl NS(=O)(=O)C1=C(Cl)C=C2NC=NS(=O)(=O)C2=C1 |
|
| Synonym |
chlorothiazide Chlorothiazide 6-chloro-1,1-dioxo-4H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide chlorothiazidum 6-Chloro-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[1,2,4]thiadiazine-7-sulfonic acid amide C7H6ClN3O4S2 6-chloro-7-sulfamoyl-2H-1,2,4-benzothiadiazine 1,1-dioxide clorotiazida 6-chloro-4H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide |
|
| xref |
ChEMBL:3712385 Drugs Product Database (DPD):231169 ChEMBL:10891117 Patent:US2809194 PharmGKB:PA448953 National Drug Code Directory:0378-0150-01 DrugBank:DB00880 RxList:http://www.rxlist.com/cgi/generic2/chloroth.htm Wikipedia:Chlorothiazide CASRN:58-94-6 KEGG DRUG:D00519 ChemSpider:2619 ChEBI:3640 Beilstein:1084805 ChEMBL:2160536 PubChem Compound:2720 PubChem Substance:46507032 KEGG COMPOUND:C07461 Drugs.com:http://www.drugs.com/cdi/chlorothiazide.html NIST Chemistry WebBook:58-94-6 |
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| subClassOf |