loading...| Preferred Name |
cephalexin |
|
| Synonyms |
C16H17N3O4S Ceporexin Celexin 7-(D-alpha-Aminophenylacetamido)desacetoxycephalosporanic acid cefalexine Cefalexin cefalexinum (6R,7R)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid cefalexina CEX (6R,7R)-7-[(2R)-2-amino-2-phenylacetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Cepastar Cephacillin 7beta-[(2R)-2-amino-2-phenylacetamido]-3-methyl-3,4-didehydrocepham-4-carboxylic acid Cepexin 7-beta-(D-alpha-Amino-alpha-phenylacetylamino)-3-methyl-3-cephem-4-carboxylic acid |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_3534 |
|
| AHFScode |
08:12.06.04 |
|
| ATCCode |
J01DB01 |
|
| CASRN |
15686-71-2 |
|
| DBBrand |
servispor alsporin lonflex nufex ceporex forte cepastar voxxim keflex l-keflex ceporexin-e lexibiotico tepaxin oracef cephaxin keftab cefalin madlexin celexin uphalexin mamalexin pectril cepol lafarine cophalexin factagard roceph larixin cepexin panixine disperdose erocetin medoxine sporidex winlex neokef syncl sinthecillin kefalospes alcephin kekrinal zozarine cefa-iskia oriphex durantel neolexina keforal kidolex pyassan cefaleksin felexin synecl ospexin cephin alexin sporicef tokiolexin carnosporin lopilexin mamlexin fexin sartosona lenocef sialexin check ceporexin cephacillin kefolan keflet ortisporina novolexin durantel ds cefadin oroxin ceforal cefax cefovit ibilex cefadal sepexin ceporexine palitrex ed a-ceph ceporex biocef cefaseptin syncle cefadina sanaxin inphalex ibrexin cefablan cephanasten sencephalin cefaloto |
|
| DBname |
cephalexin |
|
| DBSynonym |
cefalexina [inn-spanish] cephalexin hydrate cex cephalexin 1-hydrate cefalexin cefalexin sodium cefalessina [dcit] cephalexinum cephalexine cefalexinum [inn-latin] cephalexin monohydrate cefalexine [inn-french] |
|
| Definition |
A semisynthetic first-generation cephalosporin antibiotic having methyl and beta-(2R)-2-amino-2-phenylacetamido groups at the 3- and 7- of the cephem skeleton, respectively. It is effective against both Gram-negative and Gram-positive organisms, and is used for treatment of infections of the skin, respiratory tract and urinary tract. |
|
| has effect |
http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000449 http://purl.obolibrary.org/obo/OAE_0000453 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000596 http://purl.obolibrary.org/obo/OAE_0000825 http://purl.obolibrary.org/obo/OAE_0000512 http://purl.obolibrary.org/obo/OAE_0001333 http://purl.obolibrary.org/obo/OAE_0001707 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000210 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000365 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000920 http://purl.obolibrary.org/obo/OAE_0000287 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0001275 http://purl.obolibrary.org/obo/OAE_0000268 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0001106 http://purl.obolibrary.org/obo/OAE_0000968 http://purl.obolibrary.org/obo/OAE_0000034 http://purl.obolibrary.org/obo/OAE_0000385 http://purl.obolibrary.org/obo/OAE_0000468 http://purl.obolibrary.org/obo/OAE_0001217 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000374 |
|
| has pharmacological target |
http://purl.obolibrary.org/obo/dinto_0413 http://purl.obolibrary.org/obo/dinto_3285 http://purl.obolibrary.org/obo/dinto_3289 |
|
| has role | ||
| InChI |
InChI=1S/C16H17N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1 |
|
| InChIKey |
InChIKey=ZAIPMKNFIOOWCQ-UEKVPHQBSA-N |
|
| inhibits |
http://purl.obolibrary.org/obo/dinto_0413 http://purl.obolibrary.org/obo/dinto_1975 http://purl.obolibrary.org/obo/dinto_3285 http://purl.obolibrary.org/obo/dinto_3289 http://purl.obolibrary.org/obo/dinto_1920 http://purl.obolibrary.org/obo/dinto_0758 http://purl.obolibrary.org/obo/dinto_4065 http://purl.obolibrary.org/obo/dinto_2004 |
|
| is metabolised by | ||
| is transported by |
http://purl.obolibrary.org/obo/dinto_1812 |
|
| label |
cephalexin |
|
| may interact with | ||
| prefixIRI |
obo2:CHEBI_3534 |
|
| prefLabel |
cephalexin |
|
| related with | ||
| SMILES |
[H][C@]12SCC(C)=C(N1C(=O)[C@H]2NC(=O)[C@H](N)C1=CC=CC=C1)C(O)=O [H][C@]12SCC(C)=C(N1C(=O)[C@H]2NC(=O)[C@H](N)c1ccccc1)C(O)=O |
|
| Synonym |
C16H17N3O4S Ceporexin Celexin 7-(D-alpha-Aminophenylacetamido)desacetoxycephalosporanic acid cefalexine Cefalexin cefalexinum (6R,7R)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid cefalexina CEX (6R,7R)-7-[(2R)-2-amino-2-phenylacetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Cepastar Cephacillin 7beta-[(2R)-2-amino-2-phenylacetamido]-3-methyl-3,4-didehydrocepham-4-carboxylic acid Cepexin 7-beta-(D-alpha-Amino-alpha-phenylacetylamino)-3-methyl-3-cephem-4-carboxylic acid |
|
| xref |
CASRN:15686-71-2 CiteXplore:23545436 CiteXplore:23061564 National Drug Code Directory:16714-641-01 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/kef1213.shtml CiteXplore:23457080 PubChem Substance:46506749 Patent:US3507861 CiteXplore:12833570 CiteXplore:23811740 Drugs.com:http://www.drugs.com/cephalexin.html DrugBank:DB00567 CiteXplore:23688276 CiteXplore:22559990 ChEBI:3534 PharmGKB:PA448883 ChemSpider:25541 BindingDB:50139896 Reaxys:4238892 Drugs Product Database (DPD):828858 CiteXplore:10930630 KEGG COMPOUND:C06895 CiteXplore:1384868 CiteXplore:12569987 RxList:http://www.rxlist.com/cgi/generic/cephalex.htm Patent:US3275626 ChEMBL:655972 PubChem Compound:27447 CiteXplore:2083978 Wikipedia:http://en.wikipedia.org/wiki/Cephalexin Wikipedia:Cephalexin Beilstein:965503 KEGG DRUG:D00263 |
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| subClassOf |