loading...| Preferred Name |
ceftibuten |
|
| Synonyms |
ceftibuteno cis-ceftibuten (+)-(6R,7R)-7-((Z)-2-(2-amino-4-thiazolyl)-4-carboxycrotonamido)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enoyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ceftibutenum 7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enoyl]amino}-3,4-didehydrocepham-4-carboxylic acid C15H14N4O6S2 ceftibutene ceftibuten |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_3510 |
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| altId |
CHEBI:554578 |
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| ATCCode |
J01DD14 |
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| CASRN |
97519-39-6 |
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| DBBrand |
cedax |
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| DBname |
ceftibuten |
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| Definition |
A third-generation cephalosporin antibiotic with a [(2Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enoyl]amino substituent at the 7 position of the cephem skeleton. An orally-administered agent, ceftibuten is used as the dihydrate to treat urinary-tract and respiratory-tract infections. |
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| has pharmacological target |
http://purl.obolibrary.org/obo/dinto_3095 http://purl.obolibrary.org/obo/dinto_0081 |
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| has role | ||
| InChI |
InChI=1S/C15H14N4O6S2/c16-15-17-7(5-27-15)6(1-2-9(20)21)11(22)18-10-12(23)19-8(14(24)25)3-4-26-13(10)19/h1,3,5,10,13H,2,4H2,(H2,16,17)(H,18,22)(H,20,21)(H,24,25)/b6-1-/t10-,13-/m1/s1 |
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| InChIKey |
InChIKey=UNJFKXSSGBWRBZ-BJCIPQKHSA-N |
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| inhibits |
http://purl.obolibrary.org/obo/dinto_4065 http://purl.obolibrary.org/obo/dinto_3095 http://purl.obolibrary.org/obo/dinto_2004 http://purl.obolibrary.org/obo/dinto_0081 |
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| is transported by | ||
| label |
ceftibuten |
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| prefixIRI |
obo2:CHEBI_3510 |
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| prefLabel |
ceftibuten |
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| SMILES |
[H][C@]12SCC=C(N1C(=O)[C@H]2NC(=O)C(=C/CC(O)=O)\\c1csc(N)n1)C(O)=O [H][C@]12SCC=C(N1C(=O)[C@H]2NC(=O)C(=C/CC(O)=O)\C1=CSC(N)=N1)C(O)=O |
|
| Synonym |
ceftibuteno cis-ceftibuten (+)-(6R,7R)-7-((Z)-2-(2-amino-4-thiazolyl)-4-carboxycrotonamido)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enoyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ceftibutenum 7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enoyl]amino}-3,4-didehydrocepham-4-carboxylic acid C15H14N4O6S2 ceftibutene ceftibuten |
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| xref |
RxList:http://www.rxlist.com/cgi/generic/ceftibuten.htm DrugBank:DB01415 CASRN:97519-39-6 KEGG DRUG:D00922 Wikipedia:http://en.wikipedia.org/wiki/Ceftibuten Beilstein:5892046 Wikipedia:Ceftibuten Drugs.com:http://www.drugs.com/cdi/ceftibuten.html PubChem Compound:5282242 KEGG COMPOUND:C08117 PharmGKB:PA164744555 National Drug Code Directory:45809-401-20 Patent:EP136721 PubChem Substance:46507324 Patent:US4634697 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/ced1075.shtml ChemSpider:4445418 ChEBI:3510 |
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| subClassOf |