The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

cefoperazone

Synonyms

cefoperazono

cefoperazonum

(6R,7R)-7-(2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-(4-hydroxyphenyl)acetamido)-3-{[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

cefoperazone

CPZ

(6R,7R)-7-((R)-2-(4-Ethyl-2,3-dioxo-1-piperazinylcarboxamido)-2-(4-hydroxyphenyl)acetamido)-3-((1-methyl-1H-tetrazol-5-yl)thiomethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-2-carbonsaeure

C25H27N9O8S2

7beta-{[{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}(4-hydroxyphenyl)acetyl]amino}-3-[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl-3,4-didehydrocepham-4-carboxylic acid

(6R,7R)-7-{[{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}(4-hydroxyphenyl)acetyl]amino}-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(6R,7R)-7-[[2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Cefoperazone

ID

http://purl.obolibrary.org/obo/CHEBI_3493

altId

CHEBI:258120

ATCCode

J01DD12

CASRN

62893-19-0

DBBrand

cefobid

DBname

cefoperazone

DBSynonym

cefoperazonum [inn-latin]

cefoperazono [inn-spanish]

Definition

A semi-synthetic parenteral cephalosporin with a tetrazolyl moiety that confers beta-lactamase resistance.

has effect

http://purl.obolibrary.org/obo/OAE_0001333

http://purl.obolibrary.org/obo/OAE_0000920

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0001135

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0001217

http://purl.obolibrary.org/obo/OAE_0000194

http://purl.obolibrary.org/obo/OAE_0001463

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000210

http://purl.obolibrary.org/obo/OAE_0000825

http://purl.obolibrary.org/obo/OAE_0000584

has pharmacological target

http://purl.obolibrary.org/obo/dinto_1849

http://purl.obolibrary.org/obo/dinto_0081

http://purl.obolibrary.org/obo/dinto_2744

http://purl.obolibrary.org/obo/dinto_3995

http://purl.obolibrary.org/obo/dinto_1855

http://purl.obolibrary.org/obo/dinto_1854

http://purl.obolibrary.org/obo/dinto_0360

http://purl.obolibrary.org/obo/dinto_3095

http://purl.obolibrary.org/obo/dinto_2925

has role

http://purl.obolibrary.org/obo/CHEBI_36047

InChI

InChI=1S/C25H27N9O8S2/c1-3-32-8-9-33(21(39)20(32)38)24(42)27-15(12-4-6-14(35)7-5-12)18(36)26-16-19(37)34-17(23(40)41)13(10-43-22(16)34)11-44-25-28-29-30-31(25)2/h4-7,15-16,22,35H,3,8-11H2,1-2H3,(H,26,36)(H,27,42)(H,40,41)/t15?,16-,22-/m1/s1

InChIKey

InChIKey=GCFBRXLSHGKWDP-WTKTZPJXSA-N

inhibits

http://purl.obolibrary.org/obo/dinto_1849

http://purl.obolibrary.org/obo/dinto_0081

http://purl.obolibrary.org/obo/dinto_2744

http://purl.obolibrary.org/obo/dinto_1977

http://purl.obolibrary.org/obo/dinto_3995

http://purl.obolibrary.org/obo/dinto_1855

http://purl.obolibrary.org/obo/dinto_1854

http://purl.obolibrary.org/obo/dinto_4301

http://purl.obolibrary.org/obo/dinto_0360

http://purl.obolibrary.org/obo/dinto_0520

http://purl.obolibrary.org/obo/dinto_1975

http://purl.obolibrary.org/obo/dinto_3095

http://purl.obolibrary.org/obo/dinto_2925

label

cefoperazone

may interact with

http://purl.obolibrary.org/obo/dinto_DB00798

http://purl.obolibrary.org/obo/CHEBI_2637

http://purl.obolibrary.org/obo/dinto_DB00955

http://purl.obolibrary.org/obo/dinto_DB00684

prefixIRI

obo2:CHEBI_3493

prefLabel

cefoperazone

related with

http://purl.obolibrary.org/obo/dinto_0217

SMILES

[H][C@]12SCC(CSc3nnnn3C)=C(N1C(=O)[C@@]2([H])NC(=O)C(NC(=O)N1CCN(CC)C(=O)C1=O)c1ccc(O)cc1)C(O)=O

[H][C@]12SCC(CSC3=NN=NN3C)=C(N1C(=O)[C@H]2NC(=O)C(NC(=O)N1CCN(CC)C(=O)C1=O)C1=CC=C(O)C=C1)C(O)=O

Synonym

cefoperazono

cefoperazonum

(6R,7R)-7-(2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-(4-hydroxyphenyl)acetamido)-3-{[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

cefoperazone

CPZ

(6R,7R)-7-((R)-2-(4-Ethyl-2,3-dioxo-1-piperazinylcarboxamido)-2-(4-hydroxyphenyl)acetamido)-3-((1-methyl-1H-tetrazol-5-yl)thiomethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-2-carbonsaeure

C25H27N9O8S2

7beta-{[{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}(4-hydroxyphenyl)acetyl]amino}-3-[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl-3,4-didehydrocepham-4-carboxylic acid

(6R,7R)-7-{[{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}(4-hydroxyphenyl)acetyl]amino}-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(6R,7R)-7-[[2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Cefoperazone

xref

CiteXplore:1384868

ChEBI:3493

Wikipedia:http://en.wikipedia.org/wiki/Cefoperazone

KEGG COMPOUND:C06883

DrugBank:DB01329

ChemSpider:40204

CASRN:62893-19-0

National Drug Code Directory:0049-1201-83

KEGG DRUG:D07645

PharmGKB:PA448849

PubChem Substance:46504543

PubChem Compound:44185

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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