The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

butorphanol

Synonyms

C21H29NO2

(-)-butorphanol

17-(cyclobutylmethyl)morphinan-3,14-diol

butorphanol

BUTORPHANOL

(-)-N-cyclobutylmethyl-3,14-dihydroxymorphinan

Butorphanol

(-)-17-(cyclobutylmethyl)morphinan-3,14-diol

butorphanolum

(1S,9R,10S)-17-(cyclobutylmethyl)-17-azatetracyclo[7.5.3.0^{1,10}.0^{2,7}]heptadeca-2(7),3,5-triene-4,10-diol

butorfanol

ID

http://purl.obolibrary.org/obo/CHEBI_3242

activates

http://purl.obolibrary.org/obo/dinto_3960

http://purl.obolibrary.org/obo/dinto_0760

AHFScode

28:08.12

altId

CHEBI:145838

ATCCode

N02AF01

CASRN

58786-99-5

DBBrand

stadol

stadol ns

moradol

beforal

DBname

butorphanol

DBSynonym

butorfanol [inn-spanish]

butorphanolum [inn-latin]

butorphanol tartrate

butorfanol

Definition

Levorphanol in which a hydrogen at position 14 of the morphinan skeleton is substituted by hydroxy and one of the hydrogens of the N-methyl group is substituted by cyclopropyl. A semi-synthetic opioid agonist-antagonist analgesic, it is used as its (S,S)-tartaric acid salt for relief or moderate to severe pain.

has effect

http://purl.obolibrary.org/obo/OAE_0000505

http://purl.obolibrary.org/obo/OAE_0000355

http://purl.obolibrary.org/obo/OAE_0000400

http://purl.obolibrary.org/obo/OAE_0000401

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0000205

http://purl.obolibrary.org/obo/OAE_0000567

http://purl.obolibrary.org/obo/OAE_0000842

http://purl.obolibrary.org/obo/OAE_0001509

http://purl.obolibrary.org/obo/OAE_0000462

http://purl.obolibrary.org/obo/OAE_0000473

http://purl.obolibrary.org/obo/OAE_0000888

http://purl.obolibrary.org/obo/OAE_0000391

http://purl.obolibrary.org/obo/OAE_0000898

http://purl.obolibrary.org/obo/OAE_0000335

http://purl.obolibrary.org/obo/OAE_0000300

http://purl.obolibrary.org/obo/OAE_0001291

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000406

http://purl.obolibrary.org/obo/OAE_0000396

http://purl.obolibrary.org/obo/OAE_0001373

http://purl.obolibrary.org/obo/OAE_0000512

http://purl.obolibrary.org/obo/OAE_0000353

http://purl.obolibrary.org/obo/OAE_0000306

http://purl.obolibrary.org/obo/OAE_0000479

http://purl.obolibrary.org/obo/OAE_0000606

http://purl.obolibrary.org/obo/OAE_0002206

http://purl.obolibrary.org/obo/OAE_0000517

http://purl.obolibrary.org/obo/OAE_0000470

http://purl.obolibrary.org/obo/OAE_0000587

http://purl.obolibrary.org/obo/OAE_0000597

http://purl.obolibrary.org/obo/OAE_0000365

http://purl.obolibrary.org/obo/OAE_0000343

http://purl.obolibrary.org/obo/OAE_0001369

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0000542

http://purl.obolibrary.org/obo/OAE_0000508

http://purl.obolibrary.org/obo/OAE_0000382

http://purl.obolibrary.org/obo/OAE_0000403

http://purl.obolibrary.org/obo/OAE_0000414

http://purl.obolibrary.org/obo/OAE_0000358

http://purl.obolibrary.org/obo/OAE_0000460

http://purl.obolibrary.org/obo/OAE_0000402

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000310

http://purl.obolibrary.org/obo/OAE_0000645

http://purl.obolibrary.org/obo/OAE_0000510

http://purl.obolibrary.org/obo/OAE_0000465

http://purl.obolibrary.org/obo/OAE_0000394

http://purl.obolibrary.org/obo/OAE_0000350

http://purl.obolibrary.org/obo/OAE_0000395

http://purl.obolibrary.org/obo/OAE_0000166

http://purl.obolibrary.org/obo/OAE_0000660

http://purl.obolibrary.org/obo/OAE_0000602

http://purl.obolibrary.org/obo/OAE_0000536

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000443

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0000607

http://purl.obolibrary.org/obo/OAE_0000373

http://purl.obolibrary.org/obo/OAE_0000551

has pharmacological target

http://purl.obolibrary.org/obo/dinto_3960

http://purl.obolibrary.org/obo/dinto_0760

http://purl.obolibrary.org/obo/dinto_2787

has role

http://purl.obolibrary.org/obo/CHEBI_51177

http://purl.obolibrary.org/obo/CHEBI_55322

http://purl.obolibrary.org/obo/CHEBI_35482

http://purl.obolibrary.org/obo/CHEBI_59282

InChI

InChI=1S/C21H29NO2/c23-17-7-6-16-12-19-21(24)9-2-1-8-20(21,18(16)13-17)10-11-22(19)14-15-4-3-5-15/h6-7,13,15,19,23-24H,1-5,8-12,14H2/t19-,20+,21-/m1/s1

InChIKey

InChIKey=IFKLAQQSCNILHL-QHAWAJNXSA-N

label

butorphanol

may interact with

http://purl.obolibrary.org/obo/dinto_DB00427

http://purl.obolibrary.org/obo/CHEBI_4717

http://purl.obolibrary.org/obo/dinto_DB06274

prefixIRI

obo2:CHEBI_3242

prefLabel

butorphanol

related with

http://purl.obolibrary.org/obo/dinto_2787

SMILES

Oc1ccc2C[C@H]3N(CC[C@@]4(CCCC[C@@]34O)c2c1)CC1CCC1

[H][C@@]12CC3=C(C=C(O)C=C3)[C@]3(CCCC[C@@]13O)CCN2CC1CCC1

Synonym

C21H29NO2

(-)-butorphanol

17-(cyclobutylmethyl)morphinan-3,14-diol

butorphanol

BUTORPHANOL

(-)-N-cyclobutylmethyl-3,14-dihydroxymorphinan

Butorphanol

(-)-17-(cyclobutylmethyl)morphinan-3,14-diol

butorphanolum

(1S,9R,10S)-17-(cyclobutylmethyl)-17-azatetracyclo[7.5.3.0^{1,10}.0^{2,7}]heptadeca-2(7),3,5-triene-4,10-diol

butorfanol

xref

CASRN:42408-82-2

ChEMBL:6767032

Drugs.com:http://www.drugs.com/cdi/butorphanol-solution.html

National Drug Code Directory:0378-9639-43

PubChem Compound:6916249

BindingDB:50240437

ChEBI:3242

Drugs Product Database (DPD):844977

ChEMBL:6114178

Wikipedia:http://en.wikipedia.org/wiki/Butorphanol

ChEMBL:6796691

PharmGKB:PA164745398

DrugBank:DB00611

Patent:DE2243961

KEGG DRUG:D03197

Wikipedia:Butorphanol

Beilstein:8134188

ChemSpider:4514667

ChEMBL:7192744

ChEMBL:6166748

RxList:http://www.rxlist.com/cgi/generic2/butor.htm

Patent:US3819635

Patent:US3775414

KEGG COMPOUND:C06863

PubChem Substance:46507553

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.549.686.165 RH-MESH LOOM
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http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61659 NCIT LOOM
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http://purl.bioontology.org/ontology/NDDF/004635 NDDF LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/373467000 SNOMEDCT LOOM
http://stirdf.jst.go.jp/id/200907028895922511 IOBC LOOM
http://purl.obolibrary.org/obo/CHEBI_3242 CHEBI LOOM
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http://purl.jp/bio/4/id/200906068705993149 IOBC LOOM
http://purl.jp/bio/4/id/200906068705993149 IOBC LOOM
http://purl.bioontology.org/ontology/MESH/D002077 MESH LOOM
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