loading...| Preferred Name |
tazarotene |
|
| Synonyms |
ethyl 6-[(4,4-dimethyl-3,4-dihydro-2H-thiochromen-6-yl)ethynyl]nicotinate C21H21NO2S ethyl 6-[2-(4,4-dimethyl-3,4-dihydro-2H-1-benzothiopyran-6-yl)ethynyl]pyridine-3-carboxylate tazarotenum Zorac tazaroteno tazarotene Avage Tazorac |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_32184 |
|
| activates |
http://purl.obolibrary.org/obo/dinto_1682 http://purl.obolibrary.org/obo/dinto_3327 |
|
| AHFScode |
84:92.00 |
|
| ATCCode |
D05AX05 |
|
| CASRN |
118292-40-3 |
|
| DBBrand |
tazarotene [usan:inn] tazorac zorac |
|
| DBname |
tazarotene |
|
| Definition |
A carboxylic ester that is the ethyl ester of tazarotenic acid. A prodrug for tazarotenic acid, it is used for the treatment of psoriasis, acne, and sun-damaged skin. |
|
| has effect |
http://purl.obolibrary.org/obo/OAE_0000303 http://purl.obolibrary.org/obo/OAE_0000557 http://purl.obolibrary.org/obo/OAE_0000805 http://purl.obolibrary.org/obo/OAE_0001397 http://purl.obolibrary.org/obo/OAE_0000687 http://purl.obolibrary.org/obo/OAE_0000086 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0001139 http://purl.obolibrary.org/obo/OAE_0001052 |
|
| has pharmacological target |
http://purl.obolibrary.org/obo/dinto_1682 http://purl.obolibrary.org/obo/dinto_3327 |
|
| has role |
http://purl.obolibrary.org/obo/CHEBI_50905 |
|
| InChI |
InChI=1S/C21H21NO2S/c1-4-24-20(23)16-7-9-17(22-14-16)8-5-15-6-10-19-18(13-15)21(2,3)11-12-25-19/h6-7,9-10,13-14H,4,11-12H2,1-3H3 |
|
| InChIKey |
InChIKey=OGQICQVSFDPSEI-UHFFFAOYSA-N |
|
| is metabolised by | ||
| label |
tazarotene |
|
| prefixIRI |
obo2:CHEBI_32184 |
|
| prefLabel |
tazarotene |
|
| SMILES |
CCOC(=O)C1=CN=C(C=C1)C#CC1=CC2=C(SCCC2(C)C)C=C1 CCOC(=O)c1ccc(nc1)C#Cc1ccc2SCCC(C)(C)c2c1 |
|
| Synonym |
ethyl 6-[(4,4-dimethyl-3,4-dihydro-2H-thiochromen-6-yl)ethynyl]nicotinate C21H21NO2S ethyl 6-[2-(4,4-dimethyl-3,4-dihydro-2H-1-benzothiopyran-6-yl)ethynyl]pyridine-3-carboxylate tazarotenum Zorac tazaroteno tazarotene Avage Tazorac |
|
| xref |
HMDB:HMDB14937 Drugs.com:http://www.drugs.com/cdi/tazarotene-cream.html DrugBank:DB00799 Patent:US5089509 KEGG COMPOUND:C12531 PubChem Substance:46508992 PubChem Compound:5381 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/taz1429.shtml KEGG DRUG:D01132 Wikipedia:Tazarotene ChEMBL:595572 Wikipedia:http://en.wikipedia.org/wiki/Tazarotene National Drug Code Directory:0023-9236-30 CASRN:118292-40-3 Beilstein:8159145 RxList:http://www.rxlist.com/cgi/generic3/avage.htm PharmGKB:PA164746821 ChemSpider:5188 Patent:EP284288 Drugs Product Database (DPD):2243894 ChEBI:32184 |
|
| subClassOf |