The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

bumetanide

Synonyms

3-butylamino-4-phenoxy-5-sulfamoylbenzoic acid

C17H20N2O5S

bumetanida

bumetanidum

3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid

3-butylamino-4-(phenoxy)-5-sulfamoylbenzoic acid

bumetanide

3-butylamino-4-phenoxy-5-sulfamoyl-benzoic acid

3-(aminosulfonyl)-5-(butylamino)-4-phenoxybenzoic acid

ID

http://purl.obolibrary.org/obo/CHEBI_3213

AHFScode

40:28.08

altId

CHEBI:239281

ATCCode

C03CA02

blocks

http://purl.obolibrary.org/obo/dinto_0341

CASRN

28395-03-1

DBBrand

bumex

lunetoron

lixil

fordiuran

fontego

burine

burinex

segurex

DBname

bumetanide

DBSynonym

bumetanida [inn-spanish]

bumetanidum [inn-latin]

Definition

4-Phenoxybenzoic acid in which the hydrogens ortho to the phenoxy group are substituted by butylamino and sulfamoyl groups. Bumetanide is a diuretic, and is used for treatment of oedema associated with congestive heart failure, hepatic and renal disease.

has effect

http://purl.obolibrary.org/obo/OAE_0000081

http://purl.obolibrary.org/obo/OAE_0000494

http://purl.obolibrary.org/obo/OAE_0000505

http://purl.obolibrary.org/obo/OAE_0000401

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0000643

http://purl.obolibrary.org/obo/OAE_0001448

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000545

http://purl.obolibrary.org/obo/OAE_0000406

http://purl.obolibrary.org/obo/OAE_0001135

http://purl.obolibrary.org/obo/OAE_0001053

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0001364

http://purl.obolibrary.org/obo/OAE_0000586

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0000460

http://purl.obolibrary.org/obo/OAE_0000402

http://purl.obolibrary.org/obo/OAE_0000034

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0000373

http://purl.obolibrary.org/obo/OAE_0000551

has pharmacological target

http://purl.obolibrary.org/obo/dinto_1147

http://purl.obolibrary.org/obo/dinto_4037

http://purl.obolibrary.org/obo/dinto_1007

http://purl.obolibrary.org/obo/dinto_0231

has role

http://purl.obolibrary.org/obo/CHEBI_35498

InChI

InChI=1S/C17H20N2O5S/c1-2-3-9-19-14-10-12(17(20)21)11-15(25(18,22)23)16(14)24-13-7-5-4-6-8-13/h4-8,10-11,19H,2-3,9H2,1H3,(H,20,21)(H2,18,22,23)

InChIKey

InChIKey=MAEIEVLCKWDQJH-UHFFFAOYSA-N

induces

http://purl.obolibrary.org/obo/dinto_2116

inhibits

http://purl.obolibrary.org/obo/dinto_1974

http://purl.obolibrary.org/obo/dinto_1977

http://purl.obolibrary.org/obo/dinto_4301

http://purl.obolibrary.org/obo/dinto_1147

http://purl.obolibrary.org/obo/dinto_4037

http://purl.obolibrary.org/obo/dinto_0520

http://purl.obolibrary.org/obo/dinto_1975

http://purl.obolibrary.org/obo/dinto_1007

http://purl.obolibrary.org/obo/dinto_0231

is transported by

http://purl.obolibrary.org/obo/dinto_1974

http://purl.obolibrary.org/obo/dinto_1987

label

bumetanide

may interact with

http://purl.obolibrary.org/obo/dinto_DB00519

http://purl.obolibrary.org/obo/dinto_DB01396

http://purl.obolibrary.org/obo/CHEBI_17076

http://purl.obolibrary.org/obo/CHEBI_4551

http://purl.obolibrary.org/obo/dinto_DB00798

http://purl.obolibrary.org/obo/CHEBI_59594

http://purl.obolibrary.org/obo/CHEBI_5855

http://purl.obolibrary.org/obo/dinto_DB01404

http://purl.obolibrary.org/obo/dinto_DB01172

http://purl.obolibrary.org/obo/CHEBI_31468

http://purl.obolibrary.org/obo/CHEBI_9352

http://purl.obolibrary.org/obo/CHEBI_2637

http://purl.obolibrary.org/obo/dinto_DB00955

http://purl.obolibrary.org/obo/dinto_DB00684

http://purl.obolibrary.org/obo/CHEBI_50861

http://purl.obolibrary.org/obo/CHEBI_49662

http://purl.obolibrary.org/obo/CHEBI_27899

prefixIRI

obo2:CHEBI_3213

prefLabel

bumetanide

SMILES

CCCCNc1cc(cc(c1Oc1ccccc1)S(N)(=O)=O)C(O)=O

CCCCNC1=C(OC2=CC=CC=C2)C(=CC(=C1)C(O)=O)S(N)(=O)=O

Synonym

3-butylamino-4-phenoxy-5-sulfamoylbenzoic acid

C17H20N2O5S

bumetanida

bumetanidum

3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid

3-butylamino-4-(phenoxy)-5-sulfamoylbenzoic acid

bumetanide

3-butylamino-4-phenoxy-5-sulfamoyl-benzoic acid

3-(aminosulfonyl)-5-(butylamino)-4-phenoxybenzoic acid

xref

Drugs Product Database (DPD):728284

BindingDB:25903

DrugBank:DB00887

Patent:US3806534

Wikipedia:Bumetanide

ChEBI:3213

RxList:http://www.rxlist.com/cgi/generic2/bumetan.htm

PubChem Substance:46508147

ChEMBL:3989818

ChemSpider:2377

Drugs.com:http://www.drugs.com/cdi/bumetanide.html

PubChem Compound:2471

PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/bum1058.shtml

Beilstein:2185351

PharmGKB:PA448682

Patent:DE1964503

CASRN:28395-03-1

ChEMBL:18374572

KEGG DRUG:D00247

Patent:DE1964504

Wikipedia:http://en.wikipedia.org/wiki/Bumetanide

National Drug Code Directory:0004-0125-01

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

Delete Subject Author Type Created
No notes to display
Create New Mapping

Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/RCD/b32.. RCD LOOM
http://purl.bioontology.org/ontology/VANDF/4017794 VANDF LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387498005 SNOMEDCT LOOM
http://stirdf.jst.go.jp/id/200907027423743900 IOBC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU006833 LOINC LOOM
http://purl.jp/bio/4/id/200906082003803921 IOBC LOOM
http://purl.bioontology.org/ontology/NDDF/002312 NDDF LOOM
http://purl.bioontology.org/ontology/CSP/2840-3310 CRISP LOOM
http://purl.bioontology.org/ontology/LNC/LP16052-0 LOINC LOOM
https://bioportal.bioontology.org/ontologies/FTDM.owl#bumetanide FASTO LOOM
http://www.drugbank.ca/drugs/DB00887 FTC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.559.389.127.020.452.500 RH-MESH LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005287 FASTO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005287 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005287 DMTO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005619 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005619 DMTO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146155 NDFRT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28875 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28875 NCIT LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005291 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005291 DMTO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D002034 RH-MESH LOOM
http://www.co-ode.org/ontologies/galen#Bumetanide GALEN LOOM
http://purl.bioontology.org/ontology/SNMI/C-72020 SNMI LOOM
http://purl.obolibrary.org/obo/CHEBI_3213 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_3213 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3213 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_3213 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3213 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_3213 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3213 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_3213 CHEBI SAME_URI
http://bmi.utah.edu/ontologies/hfontology/C0006376 HFO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.065.884.150 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.241.223.100.050.300.200 RH-MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/1808 RXNORM LOOM
http://purl.bioontology.org/ontology/UATC/C03CA02 ATC LOOM
http://purl.bioontology.org/ontology/MESH/D002034 MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.590.700.150 RH-MESH LOOM