The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

clobetasol propionate

Synonyms

clobetasol 17-propionate

21-chloro-9-fluoro-11beta-hydroxy-16beta-methyl-3,20-dioxopregna-1,4-dien-17-yl propanoate

clobetasol 17-propanoate

C25H32ClFO5

21-chloro-9-fluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propionate

ID

http://purl.obolibrary.org/obo/CHEBI_31414

altId

CHEBI:282070

CHEBI:205078

Definition

The 17-O-propionate ester of clobetasol. A potent corticosteroid, it is used to treat various skin disorders, including exzema and psoriasis.

has role

http://purl.obolibrary.org/obo/CHEBI_35472

InChI

InChI=1S/C25H32ClFO5/c1-5-21(31)32-25(20(30)13-26)14(2)10-18-17-7-6-15-11-16(28)8-9-22(15,3)24(17,27)19(29)12-23(18,25)4/h8-9,11,14,17-19,29H,5-7,10,12-13H2,1-4H3/t14-,17-,18-,19-,22-,23-,24-,25-/m0/s1

InChIKey

InChIKey=CBGUOGMQLZIXBE-XGQKBEPLSA-N

label

clobetasol propionate

prefixIRI

obo2:CHEBI_31414

prefLabel

clobetasol propionate

SMILES

[H][C@@]12C[C@H](C)[C@](OC(=O)CC)(C(=O)CCl)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C

Synonym

clobetasol 17-propionate

21-chloro-9-fluoro-11beta-hydroxy-16beta-methyl-3,20-dioxopregna-1,4-dien-17-yl propanoate

clobetasol 17-propanoate

C25H32ClFO5

21-chloro-9-fluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propionate

xref

CASRN:25122-46-7

KEGG DRUG:D01272

Beilstein:4769432

DrugBank:DB01013

Wikipedia:Clobetasol

ChEMBL:741189

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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