loading...| Preferred Name |
azelastine |
|
| Synonyms |
4-(4-chlorobenzyl)-2-(1-methylazepan-4-yl)phthalazin-1(2H)-one azelastinum 4-(p-Chlorobenzyl)-2-(hexahydro-1-methyl-1H-azepin-4-yl)-1-(2H)-phthalazinone 4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)-1,2-dihydrophthalazin-1-one azelastina C22H24ClN3O azelastine |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_2950 |
|
| ATCCode |
R06AX19 R01AC03 S01GX07 |
|
| blocks | ||
| CASRN |
58581-89-8 |
|
| DBBrand |
astelin optivar |
|
| DBname |
azelastine |
|
| DBSalt |
azelastine hydrochloride |
|
| DBSynonym |
azelastinum [inn-latin] azelastina [inn-spanish] |
|
| Definition |
A phthalazine compound having an oxo substituent at the 1-position, a 1-methylazepan-4-yl group at the 2-position and a 4-chlorobenzyl substituent at the 4-position. |
|
| has pharmacological target | ||
| has role |
http://purl.obolibrary.org/obo/CHEBI_37955 http://purl.obolibrary.org/obo/CHEBI_64964 http://purl.obolibrary.org/obo/CHEBI_50427 http://purl.obolibrary.org/obo/CHEBI_35523 |
|
| InChI |
InChI=1S/C22H24ClN3O/c1-25-13-4-5-18(12-14-25)26-22(27)20-7-3-2-6-19(20)21(24-26)15-16-8-10-17(23)11-9-16/h2-3,6-11,18H,4-5,12-15H2,1H3 |
|
| InChIKey |
InChIKey=MBUVEWMHONZEQD-UHFFFAOYSA-N |
|
| inhibits |
http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_0293 http://purl.obolibrary.org/obo/dinto_0291 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_1440 |
|
| is metabolised by |
http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_2990 http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_0291 http://purl.obolibrary.org/obo/dinto_0269 |
|
| label |
azelastine |
|
| may interact with |
http://purl.obolibrary.org/obo/dinto_DB01551 http://purl.obolibrary.org/obo/dinto_DB00209 http://purl.obolibrary.org/obo/dinto_DB00427 http://purl.obolibrary.org/obo/CHEBI_71013 http://purl.obolibrary.org/obo/CHEBI_27796 |
|
| prefixIRI |
obo2:CHEBI_2950 |
|
| prefLabel |
azelastine |
|
| SMILES |
CN1CCCC(CC1)N1N=C(CC2=CC=C(Cl)C=C2)C2=CC=CC=C2C1=O CN1CCCC(CC1)n1nc(Cc2ccc(Cl)cc2)c2ccccc2c1=O |
|
| Synonym |
4-(4-chlorobenzyl)-2-(1-methylazepan-4-yl)phthalazin-1(2H)-one azelastinum 4-(p-Chlorobenzyl)-2-(hexahydro-1-methyl-1H-azepin-4-yl)-1-(2H)-phthalazinone 4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)-1,2-dihydrophthalazin-1-one azelastina C22H24ClN3O azelastine |
|
| xref |
Beilstein:900747 CASRN:58581-89-8 National Drug Code Directory:0037-7025-60 Drugs.com:http://www.drugs.com/cdi/azelastine-spray.html DrugBank:DB00972 PharmGKB:PA448517 Wikipedia:http://en.wikipedia.org/wiki/Azelastine ChemSpider:2180 KEGG COMPOUND:C07768 PubChem Compound:2267 ChEMBL:127309 RxList:http://www.rxlist.com/cgi/generic/optivar.htm KEGG DRUG:D07483 PubChem Substance:46507582 Patent:BE778269 Reaxys:900747 CiteXplore:22339679 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/opt1673.shtml ChEBI:2950 DrugBank:58581-89-8 Wikipedia:Azelastine Patent:US3813384 |
|
| subClassOf |