loading...| Preferred Name |
auranofin |
|
| Synonyms |
(2,3,4,6-tetra-O-acetyl-1-thio-beta-D-glucopyranosato-kappaS(1))(triethylphosphine)gold auranofine C20H34AuO9PS Triethylphosphine gold (1-Thio-beta-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate auranofinum auranofin 2,3,4,6-Tetra-O-acetyl-1-thio-beta-D-glucopyranosato-S (triethylphosphine)gold [(2R,3R,4S,5R,6S)-3,4,5-tris(acetyloxy)-6-{[(triethyl-$l^{5}-phosphanylidene)aurio]sulfanyl}oxan-2-yl]methyl acetate Ridaura auranofina |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_2922 |
|
| AHFScode |
60:00.00 |
|
| ATCCode |
M01CB03 |
|
| CASRN |
34031-32-8 |
|
| DBBrand |
ridaura |
|
| DBname |
auranofin |
|
| DBSynonym |
auroafen |
|
| Definition |
An S-glycosyl compound consisting of 2,3,4,6-tetra-O-acetyl-1-thio-beta-D-glucopyranose with the sufur atom coordinated to (triethylphosphoranylidene)gold. It is administered orally for the treatment of active progressive rheumatoid arthritis. |
|
| has effect |
http://purl.obolibrary.org/obo/OAE_0000453 http://purl.obolibrary.org/obo/OAE_0000597 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000561 http://purl.obolibrary.org/obo/OAE_0000443 http://purl.obolibrary.org/obo/OAE_0000308 http://purl.obolibrary.org/obo/OAE_0000415 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000418 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0001025 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000920 http://purl.obolibrary.org/obo/OAE_0000608 http://purl.obolibrary.org/obo/OAE_0000287 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0001275 http://purl.obolibrary.org/obo/OAE_0000268 http://purl.obolibrary.org/obo/OAE_0000286 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0000314 http://purl.obolibrary.org/obo/OAE_0000917 http://purl.obolibrary.org/obo/OAE_0000536 http://purl.obolibrary.org/obo/OAE_0001209 http://purl.obolibrary.org/obo/OAE_0000647 http://purl.obolibrary.org/obo/OAE_0000468 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0001217 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0001166 |
|
| has pharmacological target | ||
| has role |
http://purl.obolibrary.org/obo/CHEBI_35705 |
|
| InChI |
InChI=1S/C14H20O9S.C6H15P.Au/c1-6(15)19-5-10-11(20-7(2)16)12(21-8(3)17)13(14(24)23-10)22-9(4)18;1-4-7(5-2)6-3;/h10-14,24H,5H2,1-4H3;4-6H2,1-3H3;/q;;+1/p-1/t10-,11-,12+,13-,14+;;/m1../s1 |
|
| InChIKey |
InChIKey=AUJRCFUBUPVWSZ-XTZHGVARSA-M |
|
| inhibits | ||
| label |
auranofin |
|
| prefixIRI |
obo2:CHEBI_2922 |
|
| prefLabel |
auranofin |
|
| related with | ||
| SMILES |
CC[P+](CC)(CC)[Au-]S[C@@H]1O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O CCP(CC)(CC)=[Au]S[C@@H]1O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O |
|
| Synonym |
(2,3,4,6-tetra-O-acetyl-1-thio-beta-D-glucopyranosato-kappaS(1))(triethylphosphine)gold auranofine C20H34AuO9PS Triethylphosphine gold (1-Thio-beta-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate auranofinum auranofin 2,3,4,6-Tetra-O-acetyl-1-thio-beta-D-glucopyranosato-S (triethylphosphine)gold [(2R,3R,4S,5R,6S)-3,4,5-tris(acetyloxy)-6-{[(triethyl-$l^{5}-phosphanylidene)aurio]sulfanyl}oxan-2-yl]methyl acetate Ridaura auranofina |
|
| xref |
CiteXplore:6426923 Patent:DE2051495 KEGG DRUG:D00237 CiteXplore:16036347 CiteXplore:18789312 National Drug Code Directory:65483-093-06 Reaxys:11644694 CASRN:34031-32-8 CiteXplore:17645497 CiteXplore:11071118 DrugBank:DB00995 Gmelin:112479 CiteXplore:18409052 CiteXplore:2656613 CiteXplore:10796461 ChEBI:2922 Gmelin:294107 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/rid1379.shtml Beilstein:8187029 DrugBank:34031-32-8 Wikipedia:Auranofin CiteXplore:9189058 Wikipedia:http://en.wikipedia.org/wiki/Auranofin PharmGKB:PA448510 Drugs Product Database (DPD):1916823 CiteXplore:22610278 Reaxys:14401468 Patent:US3635945 Drugs.com:http://www.drugs.com/cdi/auranofin.html CiteXplore:6426843 CiteXplore:20127591 |
|
| subClassOf |