The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

auranofin

Synonyms

auranofina

2,3,4,6-Tetra-O-acetyl-1-thio-beta-D-glucopyranosato-S (triethylphosphine)gold

Triethylphosphine gold

auranofinum

[(2R,3R,4S,5R,6S)-3,4,5-tris(acetyloxy)-6-{[(triethyl-$l^{5}-phosphanylidene)aurio]sulfanyl}oxan-2-yl]methyl acetate

auranofine

Ridaura

(2,3,4,6-tetra-O-acetyl-1-thio-beta-D-glucopyranosato-kappaS(1))(triethylphosphine)gold

C20H34AuO9PS

(1-Thio-beta-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate

auranofin

ID

http://purl.obolibrary.org/obo/CHEBI_2922

AHFScode

60:00.00

ATCCode

M01CB03

CASRN

34031-32-8

DBBrand

ridaura

DBname

auranofin

DBSynonym

auroafen

Definition

An S-glycosyl compound consisting of 2,3,4,6-tetra-O-acetyl-1-thio-beta-D-glucopyranose with the sufur atom coordinated to (triethylphosphoranylidene)gold. It is administered orally for the treatment of active progressive rheumatoid arthritis.

has effect

http://purl.obolibrary.org/obo/OAE_0000608

http://purl.obolibrary.org/obo/OAE_0001129

http://purl.obolibrary.org/obo/OAE_0000920

http://purl.obolibrary.org/obo/OAE_0001448

http://purl.obolibrary.org/obo/OAE_0001025

http://purl.obolibrary.org/obo/OAE_0000268

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0001209

http://purl.obolibrary.org/obo/OAE_0000396

http://purl.obolibrary.org/obo/OAE_0000418

http://purl.obolibrary.org/obo/OAE_0000468

http://purl.obolibrary.org/obo/OAE_0000287

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0000286

http://purl.obolibrary.org/obo/OAE_0000597

http://purl.obolibrary.org/obo/OAE_0000308

http://purl.obolibrary.org/obo/OAE_0001275

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0001217

http://purl.obolibrary.org/obo/OAE_0000402

http://purl.obolibrary.org/obo/OAE_0000415

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000453

http://purl.obolibrary.org/obo/OAE_0000647

http://purl.obolibrary.org/obo/OAE_0001166

http://purl.obolibrary.org/obo/OAE_0000314

http://purl.obolibrary.org/obo/OAE_0000211

http://purl.obolibrary.org/obo/OAE_0000602

http://purl.obolibrary.org/obo/OAE_0000536

http://purl.obolibrary.org/obo/OAE_0000917

http://purl.obolibrary.org/obo/OAE_0000561

http://purl.obolibrary.org/obo/OAE_0000443

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0000373

has pharmacological target

http://purl.obolibrary.org/obo/dinto_2005

http://purl.obolibrary.org/obo/dinto_3756

has role

http://purl.obolibrary.org/obo/CHEBI_64670

http://purl.obolibrary.org/obo/CHEBI_35705

http://purl.obolibrary.org/obo/CHEBI_35842

InChI

InChI=1S/C14H20O9S.C6H15P.Au/c1-6(15)19-5-10-11(20-7(2)16)12(21-8(3)17)13(14(24)23-10)22-9(4)18;1-4-7(5-2)6-3;/h10-14,24H,5H2,1-4H3;4-6H2,1-3H3;/q;;+1/p-1/t10-,11-,12+,13-,14+;;/m1../s1

InChIKey

InChIKey=AUJRCFUBUPVWSZ-XTZHGVARSA-M

inhibits

http://purl.obolibrary.org/obo/dinto_2005

http://purl.obolibrary.org/obo/dinto_3756

label

auranofin

prefixIRI

obo2:CHEBI_2922

prefLabel

auranofin

related with

http://purl.obolibrary.org/obo/dinto_0217

SMILES

CCP(CC)(CC)=[Au]S[C@@H]1O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O

CC[P+](CC)(CC)[Au-]S[C@@H]1O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O

Synonym

auranofina

2,3,4,6-Tetra-O-acetyl-1-thio-beta-D-glucopyranosato-S (triethylphosphine)gold

Triethylphosphine gold

auranofinum

[(2R,3R,4S,5R,6S)-3,4,5-tris(acetyloxy)-6-{[(triethyl-$l^{5}-phosphanylidene)aurio]sulfanyl}oxan-2-yl]methyl acetate

auranofine

Ridaura

(2,3,4,6-tetra-O-acetyl-1-thio-beta-D-glucopyranosato-kappaS(1))(triethylphosphine)gold

C20H34AuO9PS

(1-Thio-beta-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate

auranofin

xref

CiteXplore:6426923

CiteXplore:6426843

National Drug Code Directory:65483-093-06

CiteXplore:20127591

Patent:DE2051495

PharmGKB:PA448510

CASRN:34031-32-8

KEGG DRUG:D00237

Drugs.com:http://www.drugs.com/cdi/auranofin.html

Reaxys:11644694

CiteXplore:16036347

CiteXplore:18789312

Drugs Product Database (DPD):1916823

CiteXplore:18409052

DrugBank:34031-32-8

PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/rid1379.shtml

CiteXplore:9189058

Gmelin:294107

ChEBI:2922

Gmelin:112479

DrugBank:DB00995

CiteXplore:11071118

Wikipedia:http://en.wikipedia.org/wiki/Auranofin

CiteXplore:2656613

CiteXplore:10796461

CiteXplore:22610278

CiteXplore:17645497

Beilstein:8187029

Patent:US3635945

Wikipedia:Auranofin

Reaxys:14401468

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

Delete Subject Author Type Created
No notes to display
Create New Mapping

Delete Mapping To Ontology Source
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.691.675.249.150 RH-MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/1227 RXNORM LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387100001 SNOMEDCT LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000146358 ODAE LOOM
http://purl.obolibrary.org/obo/DRON_00013467 ODNAE LOOM
http://purl.obolibrary.org/obo/DRON_00013467 DRON LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146358 NDFRT LOOM
http://purl.bioontology.org/ontology/SNMI/C-B8210 SNMI LOOM
http://www.co-ode.org/ontologies/galen#Auranofin GALEN LOOM
http://purl.bioontology.org/ontology/UATC/M01CB03 ATC LOOM
http://purl.bioontology.org/ontology/NDDF/002398 NDDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D001310 RH-MESH LOOM
http://purl.bioontology.org/ontology/RCD/j56.. RCD LOOM
http://purl.jp/bio/4/id/200906031675805988 IOBC LOOM
http://purl.obolibrary.org/obo/CHEBI_2922 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_2922 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2922 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_2922 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2922 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_2922 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2922 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_2922 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2922 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_2922 CHEBI SAME_URI
http://bmi.utah.edu/ontologies/peontology/C0004320 RAO LOOM
http://purl.bioontology.org/ontology/MESH/D001310 MESH LOOM
http://purl.bioontology.org/ontology/VANDF/4018014 VANDF LOOM
http://www.drugbank.ca/drugs/DB00995 FTC LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65242 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65242 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65242 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65242 NCIT LOOM
http://id.loc.gov/authorities/subjects/sh85009540 FAST-TOPICAL LOOM