loading...| Preferred Name |
melphalan |
|
| Synonyms |
3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine Phenylalanine nitrogen mustard Phenylalanine mustard p-Di-(2-chloroethyl)amino-L-phenylalanine melphalanum melfalano C13H18Cl2N2O2 (2S)-2-amino-3-{4-[bis(2-chloroethyl)amino]phenyl}propanoic acid 4-(Bis(2-chloroethyl)amino)-L-phenylalanine L-3-(p-(Bis(2-chloroethyl)amino)phenyl)alanine p-Bis(beta-chloroethyl)aminophenylalanine L-Sarcolysine p-N-Bis(2-chloroethyl)amino-L-phenylalanine p-L-Sarcolysin melphalan 4-[bis(2-chloroethyl)amino]-L-phenylalanine p-N,N-bis(2-chloroethyl)amino-L-phenylalanine 3-p-(Di(2-chloroethyl)amino)-phenyl-L-alanine L-Phenylalanine mustard L-PAM |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_28876 |
|
| AHFScode |
10:00.00 |
|
| altId |
CHEBI:25815 CHEBI:6742 |
|
| ATCCode |
L01AA03 |
|
| CASRN |
148-82-3 |
|
| DBBrand |
mephalan l-sarcolysine phenylalanine mustard sarkolysin alkeran melfalan l-sarkolysin l-sarcolysin levofalan sarcolysine phenylalanine nitrogen mustard l-pam l-phenylalanine mustard |
|
| DBname |
melphalan |
|
| Definition |
A phenylalanine derivative comprising L-phenylalanine having [bis(2-chloroethyl)amino group at the 4-position on the phenyl ring. |
|
| has effect |
http://purl.obolibrary.org/obo/OAE_0000318 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000659 http://purl.obolibrary.org/obo/OAE_0000617 http://purl.obolibrary.org/obo/OAE_0000267 http://purl.obolibrary.org/obo/OAE_0000406 http://purl.obolibrary.org/obo/OAE_0000415 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000418 http://purl.obolibrary.org/obo/OAE_0000210 http://purl.obolibrary.org/obo/OAE_0000021 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000660 http://purl.obolibrary.org/obo/OAE_0000197 http://purl.obolibrary.org/obo/OAE_0001073 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0001378 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0001365 http://purl.obolibrary.org/obo/OAE_0000608 http://purl.obolibrary.org/obo/OAE_0001485 http://purl.obolibrary.org/obo/OAE_0001053 http://purl.obolibrary.org/obo/OAE_0000770 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0001463 http://purl.obolibrary.org/obo/OAE_0000375 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0000691 http://purl.obolibrary.org/obo/OAE_0001275 http://purl.obolibrary.org/obo/OAE_0000943 http://purl.obolibrary.org/obo/OAE_0001190 http://purl.obolibrary.org/obo/OAE_0000086 http://purl.obolibrary.org/obo/OAE_0001341 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001135 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000034 http://purl.obolibrary.org/obo/OAE_0000647 http://purl.obolibrary.org/obo/OAE_0000185 http://purl.obolibrary.org/obo/OAE_0000468 http://purl.obolibrary.org/obo/OAE_0001217 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000275 http://purl.obolibrary.org/obo/OAE_0000347 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000565 http://purl.obolibrary.org/obo/OAE_0000374 |
|
| has pharmacological target | ||
| has role |
http://purl.obolibrary.org/obo/CHEBI_35705 http://purl.obolibrary.org/obo/CHEBI_35610 |
|
| InChI |
InChI=1S/C13H18Cl2N2O2/c14-5-7-17(8-6-15)11-3-1-10(2-4-11)9-12(16)13(18)19/h1-4,12H,5-9,16H2,(H,18,19)/t12-/m0/s1 |
|
| InChIKey |
InChIKey=SGDBTWWWUNNDEQ-LBPRGKRZSA-N |
|
| inhibits | ||
| label |
melphalan |
|
| may interact with | ||
| prefixIRI |
obo2:CHEBI_28876 |
|
| prefLabel |
melphalan |
|
| related with | ||
| SMILES |
N[C@@H](CC1=CC=C(C=C1)N(CCCl)CCCl)C(O)=O N[C@@H](Cc1ccc(cc1)N(CCCl)CCCl)C(O)=O |
|
| Synonym |
3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine Phenylalanine nitrogen mustard Phenylalanine mustard p-Di-(2-chloroethyl)amino-L-phenylalanine melphalanum melfalano C13H18Cl2N2O2 (2S)-2-amino-3-{4-[bis(2-chloroethyl)amino]phenyl}propanoic acid 4-(Bis(2-chloroethyl)amino)-L-phenylalanine L-3-(p-(Bis(2-chloroethyl)amino)phenyl)alanine p-Bis(beta-chloroethyl)aminophenylalanine L-Sarcolysine p-N-Bis(2-chloroethyl)amino-L-phenylalanine p-L-Sarcolysin melphalan 4-[bis(2-chloroethyl)amino]-L-phenylalanine p-N,N-bis(2-chloroethyl)amino-L-phenylalanine 3-p-(Di(2-chloroethyl)amino)-phenyl-L-alanine L-Phenylalanine mustard L-PAM |
|
| xref |
CiteXplore:10937717 CiteXplore:9218926 CiteXplore:18481314 Wikipedia:Melphalan Reaxys:2816456 National Drug Code Directory:0173-0045-35 RxList:http://www.rxlist.com/cgi/generic2/melph.htm CiteXplore:8552138 CiteXplore:11914777 CiteXplore:445303 CiteXplore:7494795 Drugs Product Database (DPD):4715 Wikipedia:http://en.wikipedia.org/wiki/Melphalan DrugBank:DB01042 Patent:US3032584 Patent:US275057 CASRN:148-82-3 KEGG DRUG:D00369 CiteXplore:8951232 Patent:US108552 Patent:US3032585 CiteXplore:9250538 CiteXplore:11680815 BindingDB:50038356 Drugs.com:http://www.drugs.com/cdi/melphalan.html ChEMBL:165415 PharmGKB:PA450354 ChEBI:28876 CiteXplore:7605343 CiteXplore:10820424 |
|
| subClassOf |