The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

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Preferred Name	cytarabine
Synonyms	Cytosine arabinoside 4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone cytosine-beta-D-arabinofuranoside 4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one Cytarabine 1-beta-D-Arabinofuranosylcytosine 4-amino-1-beta-D-arabinofuranosylpyrimidin-2(1H)-one C9H13N3O5 Cytosine-1-beta-D-arabinofuranoside
ID	http://purl.obolibrary.org/obo/CHEBI_28680
AHFScode	10:00.00
altId	CHEBI:23532 CHEBI:40824 CHEBI:4074
ATCCode	L01BC01
CASRN	147-94-4
DBBrand	tarabine cytosar arabitin erpalfa cytarbel spongocytidine depocyt cytosar-u alexan depocyt (liposomal) ar3 iretin udicil arafcyt
DBname	cytarabine
DBSynonym	cytosine arabinose cytosine 1-beta-d-arabinofuranoside cytosine arabinoside cytarabina cytosine arabinofuranoside arabinosylcytosine aracytidine cytosine, beta-d-arabinoside citarabina [inn-spanish] cytosine-beta-d-arabinofuranoside beta-d-arabinosylcytosine cytosine-1-beta-d-arabinofuranoside beta-cytosine arabinoside aracytin arabinocytidine aracytine cytosine-beta-arabinoside cytarabin cytarabinoside arabinofuranosylcytosine cytarabinum [inn-latin] arac ara-c beta-arabinosylcytosine cytarabine liposome injection cytosine beta-d-arabinoside
Definition	A pyrimidine nucleoside in which cytosine is attached to D-arabinofuranose via a beta-N(1)-glycosidic bond.
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000879 http://purl.obolibrary.org/obo/OAE_0000785 http://purl.obolibrary.org/obo/OAE_0000599 http://purl.obolibrary.org/obo/OAE_0000597 http://purl.obolibrary.org/obo/OAE_0000604 http://purl.obolibrary.org/obo/OAE_0000557 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000391 http://purl.obolibrary.org/obo/OAE_0000839 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000267 http://purl.obolibrary.org/obo/OAE_0000406 http://purl.obolibrary.org/obo/OAE_0000561 http://purl.obolibrary.org/obo/OAE_0000825 http://purl.obolibrary.org/obo/OAE_0001509 http://purl.obolibrary.org/obo/OAE_0001167 http://purl.obolibrary.org/obo/OAE_0000443 http://purl.obolibrary.org/obo/OAE_0001489 http://purl.obolibrary.org/obo/OAE_0001449 http://purl.obolibrary.org/obo/OAE_0000415 http://purl.obolibrary.org/obo/OAE_0000195 http://purl.obolibrary.org/obo/OAE_0000545 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000577 http://purl.obolibrary.org/obo/OAE_0000418 http://purl.obolibrary.org/obo/OAE_0000319 http://purl.obolibrary.org/obo/OAE_0000412 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000317 http://purl.obolibrary.org/obo/OAE_0000333 http://purl.obolibrary.org/obo/OAE_0000197 http://purl.obolibrary.org/obo/OAE_0000382 http://purl.obolibrary.org/obo/OAE_0000365 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0001378 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0001288 http://purl.obolibrary.org/obo/OAE_0001365 http://purl.obolibrary.org/obo/OAE_0001485 http://purl.obolibrary.org/obo/OAE_0000403 http://purl.obolibrary.org/obo/OAE_0001053 http://purl.obolibrary.org/obo/OAE_0001055 http://purl.obolibrary.org/obo/OAE_0000632 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0001463 http://purl.obolibrary.org/obo/OAE_0000375 http://purl.obolibrary.org/obo/OAE_0000300 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0000691 http://purl.obolibrary.org/obo/OAE_0000687 http://purl.obolibrary.org/obo/OAE_0000455 http://purl.obolibrary.org/obo/OAE_0001234 http://purl.obolibrary.org/obo/OAE_0000498 http://purl.obolibrary.org/obo/OAE_0000943 http://purl.obolibrary.org/obo/OAE_0000084 http://purl.obolibrary.org/obo/OAE_0001515 http://purl.obolibrary.org/obo/OAE_0001070 http://purl.obolibrary.org/obo/OAE_0001068 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0000510 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0000533 http://purl.obolibrary.org/obo/OAE_0000341 http://purl.obolibrary.org/obo/OAE_0000414 http://purl.obolibrary.org/obo/OAE_0000469 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0001164 http://purl.obolibrary.org/obo/OAE_0000034 http://purl.obolibrary.org/obo/OAE_0000438 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000647 http://purl.obolibrary.org/obo/OAE_0000306 http://purl.obolibrary.org/obo/OAE_0001336 http://purl.obolibrary.org/obo/OAE_0000022 http://purl.obolibrary.org/obo/OAE_0000385 http://purl.obolibrary.org/obo/OAE_0000491 http://purl.obolibrary.org/obo/OAE_0000468 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0000800 http://purl.obolibrary.org/obo/OAE_0001147 http://purl.obolibrary.org/obo/OAE_0001443 http://purl.obolibrary.org/obo/OAE_0001217 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000390 http://purl.obolibrary.org/obo/OAE_0000347 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000470 http://purl.obolibrary.org/obo/OAE_0001128 http://purl.obolibrary.org/obo/OAE_0000565 http://purl.obolibrary.org/obo/OAE_0001345 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0000211 http://purl.obolibrary.org/obo/OAE_0000260 http://purl.obolibrary.org/obo/OAE_0000618 http://purl.obolibrary.org/obo/OAE_0001366 http://purl.obolibrary.org/obo/OAE_0001364 http://purl.obolibrary.org/obo/OAE_0000402 http://purl.obolibrary.org/obo/OAE_0000304
has pharmacological target	http://purl.obolibrary.org/obo/dinto_2873 http://purl.obolibrary.org/obo/dinto_2800
has role	http://purl.obolibrary.org/obo/CHEBI_35705 http://purl.obolibrary.org/obo/CHEBI_35610 http://purl.obolibrary.org/obo/CHEBI_35221 http://purl.obolibrary.org/obo/CHEBI_22587
InChI	InChI=1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7+,8-/m1/s1
InChIKey	InChIKey=UHDGCWIWMRVCDJ-CCXZUQQUSA-N
inhibits	http://purl.obolibrary.org/obo/dinto_2800
is metabolised by	http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_2370 http://purl.obolibrary.org/obo/dinto_1695 http://purl.obolibrary.org/obo/dinto_2044 http://purl.obolibrary.org/obo/dinto_0152
is transported by	http://purl.obolibrary.org/obo/dinto_0718 http://purl.obolibrary.org/obo/dinto_1979 http://purl.obolibrary.org/obo/dinto_1970 http://purl.obolibrary.org/obo/dinto_1973
label	cytarabine
may interact with	http://purl.obolibrary.org/obo/CHEBI_4551 http://purl.obolibrary.org/obo/dinto_DB00072
prefixIRI	obo2:CHEBI_28680
prefLabel	cytarabine
related with	http://purl.obolibrary.org/obo/dinto_2873
SMILES	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)c(=O)n1
Synonym	Cytosine arabinoside 4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone cytosine-beta-D-arabinofuranoside 4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one Cytarabine 1-beta-D-Arabinofuranosylcytosine 4-amino-1-beta-D-arabinofuranosylpyrimidin-2(1H)-one C9H13N3O5 Cytosine-1-beta-D-arabinofuranoside
xref	Beilstein:89175 ChEMBL:151182 National Drug Code Directory:57665-331-01 PubChem Substance:46505879 Drugs Product Database (DPD):2167883 Wikipedia:http://en.wikipedia.org/wiki/Cytarabine KEGG COMPOUND:C02961 DrugBank:DB00987 ChEBI:28680 RxList:http://www.rxlist.com/cgi/generic3/cytarabine.htm PharmGKB:PA449177 PubChem Compound:6253 PDB:AR3 Wikipedia:Cytarabine Drugs.com:http://www.drugs.com/cdi/cytarabine.html CASRN:147-94-4 ChemSpider:6017
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/CHEBI_28680	GO-PLUS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_28680	EFO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_28680	OBA	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_28680	HOIP	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_28680	CHEBI	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_28680	PDRO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_28680	BERO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_28680	TXPO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_28680	BIOMODELS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_28680	DRON	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_28680	NIFSTD	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_28680	GO-PLUS	LOOM
http://purl.obolibrary.org/obo/CHEBI_28680	EFO	LOOM
http://purl.obolibrary.org/obo/CHEBI_28680	OBA	LOOM
http://purl.obolibrary.org/obo/CHEBI_28680	HOIP	LOOM
http://purl.obolibrary.org/obo/CHEBI_28680	CHEBI	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C408	NCIT	LOOM
http://purl.obolibrary.org/obo/NCIT_C408	BERO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D13.570.065.300	RH-MESH	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00018383	PMAPP-PMO	LOOM
http://purl.obolibrary.org/obo/OMIT_0004847	OMIT	LOOM
http://stirdf.jst.go.jp/id/200907086890392751	IOBC	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D13.570.685.245.453	RH-MESH	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU059480	LOINC	LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000039015	PDQ	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#3565	OCHV	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387511003	SNOMEDCT	LOOM
http://purl.jp/bio/4/id/200906077177645175	IOBC	LOOM
http://purl.obolibrary.org/obo/MESH_D003561	BERO	LOOM
http://purl.bioontology.org/ontology/SNMI/C-78080	SNMI	LOOM
http://purl.bioontology.org/ontology/NDDF/002649	NDDF	LOOM
http://purl.obolibrary.org/obo/CHEBI_28680	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_28680	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_28680	TXPO	LOOM
http://purl.obolibrary.org/obo/CHEBI_28680	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/CHEBI_28680	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_28680	NIFSTD	LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000146419	ODAE	LOOM
http://purl.bioontology.org/ontology/RXNORM/3041	RXNORM	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D003561	RH-MESH	LOOM
http://purl.bioontology.org/ontology/LNC/LP70367-5	LOINC	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.742.680.245.453	RH-MESH	LOOM
http://purl.bioontology.org/ontology/VANDF/4018080	VANDF	LOOM
http://purl.bioontology.org/ontology/MESH/D003561	MESH	LOOM
http://www.co-ode.org/ontologies/galen#Cytarabine	GALEN	LOOM
https://go.drugbank.com/drugs/DB00987	MDM	LOOM
http://purl.bioontology.org/ontology/ATC/L01BC01	ATC	LOOM
http://www.drugbank.ca/drugs/DB00987	FTC	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0010711	OCHV	LOOM
http://purl.bioontology.org/ontology/RCD/h31..	RCD	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146419	NDFRT	LOOM