The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

amiloride

Synonyms

amiloridum

amilorida

amiloride

C6H8ClN7O

N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide

3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide

3,5-diamino-N-[amino(imino)methyl]-6-chloropyrazine-2-carboxamide

Amiloride

ID

http://purl.obolibrary.org/obo/CHEBI_2639

AHFScode

40:28.16

ATCCode

C03DB01

CASRN

2016-88-8

DBBrand

midamor

guanamprazine

amipramizid

guanamprazin

amiprazidine

amipramizide

amipramidin

DBname

amiloride

DBSynonym

amilorida [inn-spanish]

amiloride hydrochloride

amiloride hydrochloride hydrate

amiloride hcl

amyloride

amiloridum [inn-latin]

Definition

A pyrazine that has formula C6H8ClN7O.

has effect

http://purl.obolibrary.org/obo/OAE_0000494

http://purl.obolibrary.org/obo/OAE_0000505

http://purl.obolibrary.org/obo/OAE_0000412

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0000218

http://purl.obolibrary.org/obo/OAE_0001001

http://purl.obolibrary.org/obo/OAE_0000333

http://purl.obolibrary.org/obo/OAE_0000391

http://purl.obolibrary.org/obo/OAE_0000335

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000902

http://purl.obolibrary.org/obo/OAE_0000545

http://purl.obolibrary.org/obo/OAE_0000385

http://purl.obolibrary.org/obo/OAE_0000406

http://purl.obolibrary.org/obo/OAE_0000396

http://purl.obolibrary.org/obo/OAE_0001135

http://purl.obolibrary.org/obo/OAE_0000491

http://purl.obolibrary.org/obo/OAE_0000468

http://purl.obolibrary.org/obo/OAE_0000287

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0002206

http://purl.obolibrary.org/obo/OAE_0000539

http://purl.obolibrary.org/obo/OAE_0000517

http://purl.obolibrary.org/obo/OAE_0000022

http://purl.obolibrary.org/obo/OAE_0000492

http://purl.obolibrary.org/obo/OAE_0001217

http://purl.obolibrary.org/obo/OAE_0001463

http://purl.obolibrary.org/obo/OAE_0000921

http://purl.obolibrary.org/obo/OAE_0000414

http://purl.obolibrary.org/obo/OAE_0000460

http://purl.obolibrary.org/obo/OAE_0000402

http://purl.obolibrary.org/obo/OAE_0000034

http://purl.obolibrary.org/obo/OAE_0000415

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000310

http://purl.obolibrary.org/obo/OAE_0000453

http://purl.obolibrary.org/obo/OAE_0000166

http://purl.obolibrary.org/obo/OAE_0000211

http://purl.obolibrary.org/obo/OAE_0000602

http://purl.obolibrary.org/obo/OAE_0000536

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0002122

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0001309

http://purl.obolibrary.org/obo/OAE_0000607

http://purl.obolibrary.org/obo/OAE_0000373

http://purl.obolibrary.org/obo/OAE_0000551

has pharmacological target

http://purl.obolibrary.org/obo/dinto_1658

http://purl.obolibrary.org/obo/dinto_0238

http://purl.obolibrary.org/obo/dinto_0244

http://purl.obolibrary.org/obo/dinto_0913

has role

http://purl.obolibrary.org/obo/CHEBI_38633

http://purl.obolibrary.org/obo/CHEBI_35498

InChI

InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15)

InChIKey

InChIKey=XSDQTOBWRPYKKA-UHFFFAOYSA-N

inhibits

http://purl.obolibrary.org/obo/dinto_2814

http://purl.obolibrary.org/obo/dinto_1658

http://purl.obolibrary.org/obo/dinto_3036

http://purl.obolibrary.org/obo/dinto_3317

http://purl.obolibrary.org/obo/dinto_1562

http://purl.obolibrary.org/obo/dinto_4072

http://purl.obolibrary.org/obo/dinto_0238

http://purl.obolibrary.org/obo/dinto_0244

http://purl.obolibrary.org/obo/dinto_1979

http://purl.obolibrary.org/obo/dinto_1565

http://purl.obolibrary.org/obo/dinto_2721

http://purl.obolibrary.org/obo/dinto_1970

http://purl.obolibrary.org/obo/dinto_0913

label

amiloride

may interact with

http://purl.obolibrary.org/obo/dinto_DB01346

http://purl.obolibrary.org/obo/dinto_DB00519

http://purl.obolibrary.org/obo/dinto_DB01345

http://purl.obolibrary.org/obo/CHEBI_9434

http://purl.obolibrary.org/obo/dinto_DB01342

http://purl.obolibrary.org/obo/dinto_DB01344

http://purl.obolibrary.org/obo/CHEBI_31547

http://purl.obolibrary.org/obo/CHEBI_3380

http://purl.obolibrary.org/obo/dinto_DB01340

http://purl.obolibrary.org/obo/dinto_DB01341

http://purl.obolibrary.org/obo/CHEBI_8774

http://purl.obolibrary.org/obo/CHEBI_9927

http://purl.obolibrary.org/obo/CHEBI_3347

http://purl.obolibrary.org/obo/CHEBI_8024

http://purl.obolibrary.org/obo/dinto_DB00691

http://purl.obolibrary.org/obo/CHEBI_4814

http://purl.obolibrary.org/obo/CHEBI_5959

http://purl.obolibrary.org/obo/CHEBI_43755

http://purl.obolibrary.org/obo/CHEBI_28593

http://purl.obolibrary.org/obo/CHEBI_6541

http://purl.obolibrary.org/obo/CHEBI_5163

http://purl.obolibrary.org/obo/CHEBI_8713

http://purl.obolibrary.org/obo/CHEBI_50861

http://purl.obolibrary.org/obo/CHEBI_3011

http://purl.obolibrary.org/obo/dinto_DB01348

http://purl.obolibrary.org/obo/dinto_DB01347

http://purl.obolibrary.org/obo/CHEBI_4784

http://purl.obolibrary.org/obo/dinto_DB01349

prefixIRI

obo2:CHEBI_2639

prefLabel

amiloride

SMILES

NC(=N)NC(=O)c1nc(Cl)c(N)nc1N

NC(N)=NC(=O)C1=C(N)N=C(N)C(Cl)=N1

Synonym

amiloridum

amilorida

amiloride

C6H8ClN7O

N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide

3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide

3,5-diamino-N-[amino(imino)methyl]-6-chloropyrazine-2-carboxamide

Amiloride

xref

Drugs.com:http://www.drugs.com/cdi/amiloride.html

Beilstein:616612

DrugBank:DB00594

ChEMBL:189526

Wikipedia:http://en.wikipedia.org/wiki/Amiloride

RxList:http://www.rxlist.com/cgi/generic2/amilor.htm

KEGG COMPOUND:C06821

IUPHAR:2421

Patent:BE639386

Wikipedia:Amiloride

ChemSpider:15403

ChEBI:2639

Guide To Pharmacology:2421

PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/mod1272.shtml

CASRN:2609-46-3

PubChem Substance:46508156

PDB:AMR

KEGG DRUG:D07447

National Drug Code Directory:64980-151-01

BindingDB:16173

PubChem Compound:16231

PharmGKB:PA448368

Drugs Product Database (DPD):2249510

Patent:US3313813

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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http://purl.bioontology.org/ontology/CSP/2507-2912 CRISP LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#1003 OCHV LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147699 NDFRT LOOM
http://purl.bioontology.org/ontology/LNC/LP16024-9 LOINC LOOM
http://www.drugbank.ca/drugs/DB00594 FTC LOOM
http://purl.bioontology.org/ontology/UATC/C03DB01 ATC LOOM
http://purl.bioontology.org/ontology/VANDF/4019603 VANDF LOOM
https://bioportal.bioontology.org/ontologies/FTDM.owl#amiloride FASTO LOOM
http://purl.bioontology.org/ontology/LNC/MTHU006775 LOINC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0002502 OCHV LOOM
http://purl.bioontology.org/ontology/SNMI/C-72410 SNMI LOOM
http://www.co-ode.org/ontologies/galen#Amiloride GALEN LOOM
http://purl.jp/bio/4/id/200906066759071490 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D000584 RH-MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_2639 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_2639 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2639 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_2639 GO-PLUS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2639 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_2639 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2639 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_2639 FYPO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2639 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_2639 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2639 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_2639 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2639 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_2639 GO-PLUS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2639 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_2639 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2639 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_2639 FYPO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2639 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_2639 FYPO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2639 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_2639 NIFSTD SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2639 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_2639 FYPO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2639 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_2639 FYPO SAME_URI
http://id.loc.gov/authorities/subjects/sh85004476 FAST-TOPICAL LOOM
http://purl.bioontology.org/ontology/RXNORM/644 RXNORM LOOM
http://purl.bioontology.org/ontology/RCD/x01Qu RCD LOOM
http://stirdf.jst.go.jp/id/200907033781089260 IOBC LOOM
http://purl.bioontology.org/ontology/NDDF/004861 NDDF LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61633 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61633 NCIT LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387503008 SNOMEDCT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.679.149 RH-MESH LOOM
http://purl.bioontology.org/ontology/MESH/D000584 MESH LOOM
http://bmi.utah.edu/ontologies/hfontology/C0002502 HFO LOOM