The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

amikacin

Synonyms

(2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-(3-amino-3-deoxy-alpha-D-glucopyranosyloxy)-4-(6-amino-6-deoxy-alpha-D-glucopyranosyloxy)-3-hydroxycyclohexyl]-2-hydroxybutanamide

O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1->4)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1->6))-N(3)-(4-amino-L-2-hydroxybutyryl)-2-deoxy-L-streptamine

amikacina

1-N-(L(-)-gamma-amino-alpha-hydroxybutyryl)kanamycin A

amikacine

Amikacin

amikacinum

amikacin

C22H43N5O13

(2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4-{[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-3-hydroxycyclohexyl]-2-hydroxybutanamide

ID

http://purl.obolibrary.org/obo/CHEBI_2637

AHFScode

08:12.02

ATCCode

J01GB06

D06AX12

S01AA21

CASRN

37517-28-5

DBBrand

amiglyde-v

briclin

amikavet

amikin

amicacin

DBname

amikacin

DBSynonym

amikacin dihydrate

antibiotic bb-k8

bb-k8

amikacine [inn-french]

amikacin sulfate

amikacinum [inn-latin]

amikacina [inn-spanish]

amikacin base

Definition

An alpha-D-glucoside that has formula C22H43N5O13.

has effect

http://purl.obolibrary.org/obo/OAE_0000573

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0000577

http://purl.obolibrary.org/obo/OAE_0000920

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000385

http://purl.obolibrary.org/obo/OAE_0001364

http://purl.obolibrary.org/obo/OAE_0000539

http://purl.obolibrary.org/obo/OAE_0001059

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000166

http://purl.obolibrary.org/obo/OAE_0001365

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0001366

http://purl.obolibrary.org/obo/OAE_0000551

has pharmacological target

http://purl.obolibrary.org/obo/dinto_1191

has role

http://purl.obolibrary.org/obo/CHEBI_36047

http://purl.obolibrary.org/obo/CHEBI_22582

InChI

InChI=1S/C22H43N5O13/c23-2-1-8(29)20(36)27-7-3-6(25)18(39-22-16(34)15(33)13(31)9(4-24)37-22)17(35)19(7)40-21-14(32)11(26)12(30)10(5-28)38-21/h6-19,21-22,28-35H,1-5,23-26H2,(H,27,36)/t6-,7+,8-,9+,10+,11-,12+,13+,14+,15-,16+,17-,18+,19-,21+,22+/m0/s1

InChIKey

InChIKey=LKCWBDHBTVXHDL-RMDFUYIESA-N

inhibits

http://purl.obolibrary.org/obo/dinto_1191

http://purl.obolibrary.org/obo/dinto_2863

label

amikacin

may interact with

http://purl.obolibrary.org/obo/CHEBI_124991

http://purl.obolibrary.org/obo/CHEBI_47426

http://purl.obolibrary.org/obo/CHEBI_9774

http://purl.obolibrary.org/obo/CHEBI_29007

http://purl.obolibrary.org/obo/CHEBI_3491

http://purl.obolibrary.org/obo/CHEBI_3499

http://purl.obolibrary.org/obo/CHEBI_7907

http://purl.obolibrary.org/obo/CHEBI_554446

http://purl.obolibrary.org/obo/CHEBI_9513

http://purl.obolibrary.org/obo/CHEBI_61049

http://purl.obolibrary.org/obo/CHEBI_4876

http://purl.obolibrary.org/obo/dinto_DB01112

http://purl.obolibrary.org/obo/dinto_DB01226

http://purl.obolibrary.org/obo/CHEBI_4707

http://purl.obolibrary.org/obo/CHEBI_8884

http://purl.obolibrary.org/obo/CHEBI_474053

http://purl.obolibrary.org/obo/CHEBI_3495

http://purl.obolibrary.org/obo/CHEBI_59662

http://purl.obolibrary.org/obo/CHEBI_45652

http://purl.obolibrary.org/obo/CHEBI_553473

http://purl.obolibrary.org/obo/dinto_DB00214

http://purl.obolibrary.org/obo/CHEBI_3547

http://purl.obolibrary.org/obo/CHEBI_3480

http://purl.obolibrary.org/obo/CHEBI_2914

http://purl.obolibrary.org/obo/CHEBI_204928

http://purl.obolibrary.org/obo/CHEBI_3493

http://purl.obolibrary.org/obo/CHEBI_209807

http://purl.obolibrary.org/obo/CHEBI_3213

http://purl.obolibrary.org/obo/CHEBI_3508

http://purl.obolibrary.org/obo/CHEBI_9587

http://purl.obolibrary.org/obo/CHEBI_9939

http://purl.obolibrary.org/obo/CHEBI_27899

http://purl.obolibrary.org/obo/dinto_DB01336

http://purl.obolibrary.org/obo/dinto_DB01338

prefixIRI

obo2:CHEBI_2637

prefLabel

amikacin

SMILES

NCC[C@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](N)[C@H]1O

Synonym

(2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-(3-amino-3-deoxy-alpha-D-glucopyranosyloxy)-4-(6-amino-6-deoxy-alpha-D-glucopyranosyloxy)-3-hydroxycyclohexyl]-2-hydroxybutanamide

O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1->4)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1->6))-N(3)-(4-amino-L-2-hydroxybutyryl)-2-deoxy-L-streptamine

amikacina

1-N-(L(-)-gamma-amino-alpha-hydroxybutyryl)kanamycin A

amikacine

Amikacin

amikacinum

amikacin

C22H43N5O13

(2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4-{[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-3-hydroxycyclohexyl]-2-hydroxybutanamide

xref

ChEBI:2637

Wikipedia:Amikacin

KEGG DRUG:D02543

PharmGKB:PA164744372

RxList:http://www.rxlist.com/cgi/generic3/amikacin.htm

Patent:DE2234315

Patent:US3781268

Wikipedia:http://en.wikipedia.org/wiki/Amikacin

ChemSpider:34635

Drugs.com:http://www.drugs.com/cdi/amikacin.html

KEGG COMPOUND:C06820

National Drug Code Directory:0703-9032-03

Beilstein:5915117

PubChem Substance:46506386

ChEMBL:433157

PubChem Compound:37768

CASRN:37517-28-5

Drugs Product Database (DPD):2242971

DrugBank:DB00479

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61615 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61615 NCIT LOOM
http://purl.bioontology.org/ontology/UATC/S01AA21 ATC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D09.408.051.476.060 RH-MESH LOOM
http://purl.bioontology.org/ontology/MESH/D000583 MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387266001 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/RXNORM/641 RXNORM LOOM
http://purl.bioontology.org/ontology/UATC/D06AX12 ATC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147698 NDFRT LOOM
http://purl.bioontology.org/ontology/SNMI/C-52520 SNMI LOOM
http://purl.bioontology.org/ontology/NDDF/004899 NDDF LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#1001 OCHV LOOM
http://purl.bioontology.org/ontology/LNC/MTHU002886 LOINC LOOM
http://purl.bioontology.org/ontology/VANDF/4019602 VANDF LOOM
http://purl.bioontology.org/ontology/LNC/LP15005-9 LOINC LOOM
http://purl.obolibrary.org/obo/ARO_0000013 ARO LOOM
http://purl.bioontology.org/ontology/UATC/J01GB06 ATC LOOM
http://purl.bioontology.org/ontology/CPT/80150 CPT LOOM
http://purl.jp/bio/4/id/200906020001206645 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D000583 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0002499 OCHV LOOM
http://stirdf.jst.go.jp/id/200907084160026200 IOBC LOOM
http://purl.obolibrary.org/obo/CHEBI_2637 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_2637 PHIPO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2637 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_2637 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2637 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_2637 GENEPIO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2637 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_2637 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2637 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_2637 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2637 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_2637 CCONT SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2637 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_2637 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2637 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_2637 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2637 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_2637 GENEPIO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2637 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_2637 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2637 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_2637 NIFSTD SAME_URI
http://www.co-ode.org/ontologies/galen#Amikacin GALEN LOOM
http://purl.bioontology.org/ontology/RCD/e82.. RCD LOOM