loading...| Preferred Name |
lovastatin |
|
| Synonyms |
(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate LOVASTATIN Lovastatin ML-530B Mevinolin 2beta,6alpha-dimethyl-8alpha-(2-methyl-1-oxobutoxy)-mevinic acid lactone C24H36O5 InChIKey=PCZOHLXUXFIOCF-BXMDZJJMSA-N InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1 [H][C@]12[C@H](C[C@@H](C)C=C1C=C[C@H](C)[C@@H]2CC[C@@H]1C[C@@H](O)CC(=O)O1)OC(=O)[C@@H](C)CC 6alpha-methylcompactin (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(2R,4R)-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl (S)-2-methyl-butyrate Mevacor MK-803 |
|
| Definitions |
A fatty acid ester that is mevastatin carrying an additional methyl group on the carbobicyclic skeleton. It is used in as a antilipemic drug and has been found in fungal species such as Aspergillus terreus and Pleurotus ostreatus (oyster mushroom). |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_40303 |
|
| database_cross_reference |
Wikipedia:Lovastatin KEGG DRUG:75330-75-5 CiteXplore:11375168 Patent:WO2013090461 CiteXplore:18642339 CiteXplore:11483865 KEGG COMPOUND:C07074 KNApSAcK:C00000547 PDBeChem:803 ChemIDplus:3631989 KEGG DRUG:D00359 ChemIDplus:75330-75-5 Patent:CN103172602 HMDB:HMDB14372 DrugBank:DB00227 CiteXplore:24093797 Reaxys:4720754 CiteXplore:11389707 |
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| has_alternative_id |
CHEBI:6544 CHEBI:40299 |
|
| has_exact_synonym |
(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate LOVASTATIN Lovastatin |
|
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
ML-530B Mevinolin 2beta,6alpha-dimethyl-8alpha-(2-methyl-1-oxobutoxy)-mevinic acid lactone C24H36O5 InChIKey=PCZOHLXUXFIOCF-BXMDZJJMSA-N InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1 [H][C@]12[C@H](C[C@@H](C)C=C1C=C[C@H](C)[C@@H]2CC[C@@H]1C[C@@H](O)CC(=O)O1)OC(=O)[C@@H](C)CC 6alpha-methylcompactin (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(2R,4R)-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl (S)-2-methyl-butyrate Mevacor MK-803 |
|
| id |
CHEBI:40303 |
|
| imported from | ||
| label |
lovastatin |
|
| notation |
CHEBI:40303 |
|
| prefLabel |
lovastatin |
|
| textual definition |
A fatty acid ester that is mevastatin carrying an additional methyl group on the carbobicyclic skeleton. It is used in as a antilipemic drug and has been found in fungal species such as Aspergillus terreus and Pleurotus ostreatus (oyster mushroom). |
|
| subClassOf |