loading...| Preferred Name |
Barbiturate |
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| ID |
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_60f85153_5af2_4b13_bfb9_0328198e336b |
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| isDefinedBy |
Barbiturates in high doses are effective in lowering refractory intracranial hypertension but ineffective or potentially harmful as a first-line or prophylactic treatment in patients with brain injuries. High-dose barbiturate treatment acts by depressing cerebral metabolic activity. This results in a reduction in CBF, which is coupled to metabolism, and a fall in ICP. |
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| label |
Barbiturate |
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| prefixIRI |
OWLClass_60f85153_5af2_4b13_bfb9_0328198e336b |
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| prefLabel |
Barbiturate |
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| references |
Broderick, J., Connolly, S., Feldmann, E., Hanley, D., Kase, C., Krieger, D., ... & Zuccarello, M. (2007). Guidelines for the Management of Spontaneous Intracerebral Hemorrhage in Adults 2007 Update: A Guideline From the American Heart Association/American Stroke Association Stroke Council, High Blood Pressure Research Council, and the Quality of Care and Outcomes in Research Interdisciplinary Working Group: The American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists. Stroke, 38(6), 2001-2023. |
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| subClassOf |
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_bcc5e203_ae50_432a_be9b_d5c673185bbe |