Preferred Name

selective estrogen receptor modulator

Synonyms

SERM

Definitions

structurally diverse group of compounds distinguished from estrogen by their ability to bind and activate the estrogen receptor, but act as either an estrogen agonist or antagonist depending on the tissue type and hormonal milieu; classified as either first generation because they demonstrate estrogen agonist properties in the endometrium or second generation based on their patterns of tissue specificity.

ID

http://purl.bioontology.org/ontology/CSP/5005-0021

altLabel

SERM

cui

C0732611

definition

structurally diverse group of compounds distinguished from estrogen by their ability to bind and activate the estrogen receptor, but act as either an estrogen agonist or antagonist depending on the tissue type and hormonal milieu; classified as either first generation because they demonstrate estrogen agonist properties in the endometrium or second generation based on their patterns of tissue specificity.

DID

5005-0021

Inverse of RB

http://purl.bioontology.org/ontology/CSP/1025-7345

Inverse of RN

http://purl.bioontology.org/ontology/CSP/0119-1179

http://purl.bioontology.org/ontology/CSP/5001-0008

Inverse of RO

http://purl.bioontology.org/ontology/CSP/1065-7679

http://purl.bioontology.org/ontology/CSP/1025-6954

Inverse of SIB

http://purl.bioontology.org/ontology/CSP/1026-1062

http://purl.bioontology.org/ontology/CSP/1025-8791

http://purl.bioontology.org/ontology/CSP/1025-7547

http://purl.bioontology.org/ontology/CSP/2055-8048

http://purl.bioontology.org/ontology/CSP/1025-7446

http://purl.bioontology.org/ontology/CSP/2586-9048

http://purl.bioontology.org/ontology/CSP/2928-9974

http://purl.bioontology.org/ontology/CSP/4008-0079

notation

5005-0021

prefLabel

selective estrogen receptor modulator

tui

T125

T121

subClassOf

http://purl.bioontology.org/ontology/CSP/1025-7345

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