Preferred Name |
progressive supranuclear palsy |
|
Synonyms |
Steele-Richardson-Olszewski Disease Progressive supranuclear ophthalmoplegia Steele-Richardson-Olszewski Syndrome progressive supranuclear ophthalmoplegia (disorder) supranuclear palsy, progressive |
|
Definitions |
A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei (MeSH). |
|
ID |
http://www.ebi.ac.uk/efo/EFO_0002512 |
|
comment |
A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei (MeSH). |
|
alternative term |
Steele-Richardson-Olszewski Disease Progressive supranuclear ophthalmoplegia Steele-Richardson-Olszewski Syndrome progressive supranuclear ophthalmoplegia (disorder) supranuclear palsy, progressive |
|
definition source |
DOID:678 NIFSTD:birnlex_12697 |
|
label |
progressive supranuclear palsy |
|
prefixIRI |
efo:EFO_0002512 |
|
prefLabel |
progressive supranuclear palsy |
|
see also |
URI: http://www.ebi.ac.uk/cellline#supranuclear_palsy,_progressive |
|
term editor |
James Malone Ele Holloway Tomasz Adamusiak |
|
subClassOf |
http://purl.obolibrary.org/obo/DOID_539 http://purl.obolibrary.org/obo/DOID_480 http://purl.obolibrary.org/obo/DOID_231 |
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