loading...| Preferred Name |
microglial cell |
|
| Synonyms |
brain-resident macrophage microgliocyte microglia hortega cells brain macrophage MF.microglia.CNS |
|
| Definitions |
Markers: Mouse: CD11b+, F4/80+, CD68+. They represent ~12% of the cells in the CNS, but they are not uniformly distributed within the CNS. A normal adult mouse brain has approximately 3.5x10e6 microglia. Microglia are also reportedly CD3-negative, CD4-positive, CD8-negative, CD11b-positive, CD11c-high, CD14-negative, CD19-negative, CD45-low, CD56-negative, CD163-negative, CD200R-positive, CD281-positive, CD282-positive, CD283-positive, CD284-positive, CD285-positive, CD286-positive, CD287-positive, CD288-positive, CD289-positive, Gr1-negative, nestin-positive, and PU.1-positive. A central nervous system macrophage found in the parenchyma of the central nervous system. Marker include CD11b-positive, F4/80-positive, and CD68-positive. |
|
| ID |
http://purl.obolibrary.org/obo/CL_0000129 |
|
| comment |
Markers: Mouse: CD11b+, F4/80+, CD68+. They represent ~12% of the cells in the CNS, but they are not uniformly distributed within the CNS. A normal adult mouse brain has approximately 3.5x10e6 microglia. Microglia are also reportedly CD3-negative, CD4-positive, CD8-negative, CD11b-positive, CD11c-high, CD14-negative, CD19-negative, CD45-low, CD56-negative, CD163-negative, CD200R-positive, CD281-positive, CD282-positive, CD283-positive, CD284-positive, CD285-positive, CD286-positive, CD287-positive, CD288-positive, CD289-positive, Gr1-negative, nestin-positive, and PU.1-positive. |
|
| capable of | ||
| database_cross_reference |
BTO:0000962 FMA:54539 FMA:54540 BTO:0000078 |
|
| develops_from | ||
| has plasma membrane part |
http://purl.obolibrary.org/obo/PR_000001012 |
|
| has_broad_synonym |
brain macrophage |
|
| has_exact_synonym |
brain-resident macrophage microgliocyte microglia hortega cells |
|
| has_obo_namespace |
cell |
|
| has_related_synonym |
MF.microglia.CNS |
|
| imported from | ||
| label |
microglial cell |
|
| prefixIRI |
CL:0000129 |
|
| prefLabel |
microglial cell |
|
| textual definition |
A central nervous system macrophage found in the parenchyma of the central nervous system. Marker include CD11b-positive, F4/80-positive, and CD68-positive. |
|
| treeView | ||
| subClassOf |
http://purl.obolibrary.org/obo/CARO_0000006 |
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