Preferred Name

tramadol

Synonyms

(+-)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol

rac-(1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol

U-26225A

CG-315E

tramadol

tramadolum

E-265

Definitions

A racemate consisting of equal amounts of (R,R)- and (S,S)-tramadol. A centrally acting synthetic opioid analgesic, used (as the hydrochloride salt) to treat moderately severe pain. The (R,R)-enantiomer exhibits ten-fold higher analgesic potency than the (S,S)-enantiomer. Originally developed by Gruenenthal GmbH and launched in 1977, it was subsequently isolated from the root bark of the South African tree Nauclea latifolia.

ID

http://purl.obolibrary.org/obo/CHEBI_9648

charge

0

database_cross_reference

PMID:22943675

CAS:27203-92-5

PMID:23061925

PMID:23907474

KEGG:D08623

PMID:25219922

PMID:23292128

PMID:22674657

PMID:22964800

Wikipedia:Tramadol

PMID:23102445

PMID:23840975

KEGG:C07153

PMID:23756535

PMID:23543914

Reaxys:2943832

PMID:23145962

PMID:23822079

PMID:24014188

PMID:23755929

PMID:23773348

PMID:23099620

PMID:23098678

PMID:23031839

Patent:US3652589

DrugBank:DB00193

Patent:GB997399

PMID:23843224

HMDB:HMDB0014339

PMID:23825758

PMID:23962470

PMID:23328338

PMID:23872384

PMID:23668411

PMID:23095734

PMID:23433451

definition

A racemate consisting of equal amounts of (R,R)- and (S,S)-tramadol. A centrally acting synthetic opioid analgesic, used (as the hydrochloride salt) to treat moderately severe pain. The (R,R)-enantiomer exhibits ten-fold higher analgesic potency than the (S,S)-enantiomer. Originally developed by Gruenenthal GmbH and launched in 1977, it was subsequently isolated from the root bark of the South African tree Nauclea latifolia.

formula

C16H25NO2

has part

http://purl.obolibrary.org/obo/CHEBI_75725

http://purl.obolibrary.org/obo/CHEBI_75731

has role

http://purl.obolibrary.org/obo/CHEBI_35703

http://purl.obolibrary.org/obo/CHEBI_70774

http://purl.obolibrary.org/obo/CHEBI_48279

http://purl.obolibrary.org/obo/CHEBI_50949

http://purl.obolibrary.org/obo/CHEBI_51177

http://purl.obolibrary.org/obo/CHEBI_35640

http://purl.obolibrary.org/obo/CHEBI_55322

http://purl.obolibrary.org/obo/CHEBI_48876

http://purl.obolibrary.org/obo/CHEBI_64054

http://purl.obolibrary.org/obo/CHEBI_78298

http://purl.obolibrary.org/obo/CHEBI_35482

http://purl.obolibrary.org/obo/CHEBI_60643

http://purl.obolibrary.org/obo/CHEBI_48878

http://purl.obolibrary.org/obo/CHEBI_59282

has_exact_synonym

rac-(1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol

has_obo_namespace

chebi_ontology

has_related_synonym

(+-)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol

U-26225A

CG-315E

tramadol

tramadolum

E-265

id

CHEBI:9648

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

is conjugate base of

http://purl.obolibrary.org/obo/CHEBI_75736

label

tramadol

mass

263.37520

notation

CHEBI:9648

prefLabel

tramadol

treeView

http://purl.obolibrary.org/obo/CHEBI_60911

subClassOf

http://purl.obolibrary.org/obo/CHEBI_60911

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http://purl.bioontology.org/ontology/NDFRT/N0000021990 NDFRT LOOM
http://purl.jp/bio/4/id/200906018832596810 IOBC LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Tramadol APAONTO LOOM
http://www.co-ode.org/ontologies/galen#Tramadol GALEN LOOM
http://purl.bioontology.org/ontology/RCD/dji.. RCD LOOM
http://purl.bioontology.org/ontology/RXNORM/10689 RXNORM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.092.668.387.750 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/386858008 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/LNC/MTHU003394 LOINC LOOM
http://purl.bioontology.org/ontology/LNC/LP18112-0 LOINC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/108507005 SNOMEDCT LOOM
http://purl.obolibrary.org/obo/DRON_00017838 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_9648 NBO LOOM
http://purl.obolibrary.org/obo/CHEBI_9648 NBO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9648 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_9648 DINTO SAME_URI
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29507 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29507 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29507 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29507 NCIT LOOM
http://bmi.utah.edu/ontologies/peontology/C0040610 RAO LOOM
http://purl.bioontology.org/ontology/CPT/80373 CPT LOOM
http://purl.bioontology.org/ontology/VANDF/4023985 VANDF LOOM
http://purl.bioontology.org/ontology/MESH/D014147 MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.033.480.300.802 RH-MESH LOOM
http://purl.bioontology.org/ontology/UATC/N02AX02 ATC LOOM
http://www.drugbank.ca/drugs/DB00193 FTC LOOM
http://www.limics.fr/ontologies/ontoparonmed#Tramadol ONTOPARON LOOM
http://www.limics.fr/ontologies/ontoparonmed#Tramadol ONTOPARON LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D014147 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDDF/004180 NDDF LOOM