Preferred Name

pravastatin sodium

Synonyms

sodium (3R,5R)-3,5-dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]heptanoate

Definitions

An organic sodium salt that is the sodium salt of pravastatin. A reversible inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA), it is used for lowering cholesterol and preventing cardiovascular disease. It is one of the lower potency statins, but has the advantage of fewer side effects compared with lovastatin and simvastatin.

ID

http://purl.obolibrary.org/obo/CHEBI_8361

charge

0

database_cross_reference

Reaxys:4224939

PMID:1425808

KEGG:D00893

CAS:81131-70-6

PMID:1926908

Wikipedia:Parvaststin

PMID:1680649

HMDB:HMDB0005022

DrugBank:DB00175

definition

An organic sodium salt that is the sodium salt of pravastatin. A reversible inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA), it is used for lowering cholesterol and preventing cardiovascular disease. It is one of the lower potency statins, but has the advantage of fewer side effects compared with lovastatin and simvastatin.

formula

C23H35NaO7

has part

http://purl.obolibrary.org/obo/CHEBI_63660

has role

http://purl.obolibrary.org/obo/CHEBI_35821

has_exact_synonym

sodium (3R,5R)-3,5-dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]heptanoate

has_obo_namespace

chebi_ontology

id

CHEBI:8361

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

inchi

InChI=1S/C23H36O7.Na/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28;/h5-6,9,13-14,16-20,22,24-26H,4,7-8,10-12H2,1-3H3,(H,27,28);/q;+1/p-1/t13-,14-,16+,17+,18+,19-,20-,22-;/m0./s1

inchikey

VWBQYTRBTXKKOG-IYNICTALSA-M

label

pravastatin sodium

mass

446.50960

monoisotopicmass

446.22805

notation

CHEBI:8361

prefLabel

pravastatin sodium

smiles

[Na+].[H][C@]12[C@H](C[C@H](O)C=C1C=C[C@H](C)[C@@H]2CC[C@@H](O)C[C@@H](O)CC([O-])=O)OC(=O)[C@@H](C)CC

treeView

http://purl.obolibrary.org/obo/CHEBI_38700

http://purl.obolibrary.org/obo/CHEBI_87633

subClassOf

http://purl.obolibrary.org/obo/CHEBI_38700

http://purl.obolibrary.org/obo/CHEBI_87633

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