Preferred Name

apremilast

Synonyms

N-{2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide

apremilast

CC 10004

CC10004

CC-10004

OTEZLA

apremilastum

Definitions

A member of the class of isoindoles that is isoindole-1,3-dione substituted at position 4 by an acetamido group and at position 1 by a 1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl group. Used for treatment of psoriatic arthritis.

ID

http://purl.obolibrary.org/obo/CHEBI_78540

charge

0

database_cross_reference

PMID:25027606

Drug_Central:4829

PMID:24979544

PMID:24852768

KEGG:D08860

PMID:24702658

PMID:24882690

PMID:24998661

PMID:24072562

PMID:25050054

PMID:24962564

PMID:23569359

PMID:25054629

PMID:24869713

PMID:22984171

Wikipedia:Apremilast

PMID:24846499

PMID:24797159

PMID:24595547

PMID:23986162

PMID:23588944

PMID:22910104

PMID:23663752

PMID:24997741

PMID:24592316

PMID:23030767

CAS:608141-41-9

Reaxys:12446985

definition

A member of the class of isoindoles that is isoindole-1,3-dione substituted at position 4 by an acetamido group and at position 1 by a 1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl group. Used for treatment of psoriatic arthritis.

formula

C22H24N2O7S

has role

http://purl.obolibrary.org/obo/CHEBI_68844

http://purl.obolibrary.org/obo/CHEBI_35475

has_exact_synonym

N-{2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide

has_obo_namespace

chebi_ontology

has_related_synonym

apremilast

CC 10004

CC10004

CC-10004

OTEZLA

apremilastum

id

CHEBI:78540

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

inchi

InChI=1S/C22H24N2O7S/c1-5-31-19-11-14(9-10-18(19)30-3)17(12-32(4,28)29)24-21(26)15-7-6-8-16(23-13(2)25)20(15)22(24)27/h6-11,17H,5,12H2,1-4H3,(H,23,25)/t17-/m1/s1

inchikey

IMOZEMNVLZVGJZ-QGZVFWFLSA-N

label

apremilast

mass

460.50000

monoisotopicmass

460.13042

notation

CHEBI:78540

prefLabel

apremilast

smiles

CCOc1cc(ccc1OC)[C@@H](CS(C)(=O)=O)N1C(=O)c2cccc(NC(C)=O)c2C1=O

treeView

http://purl.obolibrary.org/obo/CHEBI_35850

http://purl.obolibrary.org/obo/CHEBI_13790

http://purl.obolibrary.org/obo/CHEBI_35618

http://purl.obolibrary.org/obo/CHEBI_82851

subClassOf

http://purl.obolibrary.org/obo/CHEBI_35850

http://purl.obolibrary.org/obo/CHEBI_13790

http://purl.obolibrary.org/obo/CHEBI_35618

http://purl.obolibrary.org/obo/CHEBI_82851

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