Preferred Name |
temafloxacin |
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Synonyms |
rac-1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (+-)-1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid temafloxacine temafloxacin temafloxacinum temafloxacino (+-)-temafloxacin rac-temafloxacin T 1258 A 62254 |
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Definitions |
A racemate comprising equimolar amounts of (R)- and (S)-temafloxacin. Both enantiomers both exhibit similar pharmacological profiles. Temafloxacin was briefly used (either as the free base or as the hydrochloride salt) as an antibacterial drug but was withdrawn worldwide in 1992 following reports of serious side effects, including severe hypoglycaemia, haemolytic anaemia, liver and kidney dysfunction, anaphylaxis, and death. |
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ID |
http://purl.obolibrary.org/obo/CHEBI_77788 |
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database_cross_reference |
PMID:1319872 PMID:1846917 Reaxys:4301726 DrugBank:DB01405 Patent:US4730000 Patent:EP131839 PMID:1662889 CAS:108319-06-8 PMID:1662893 Wikipedia:Temafloxacin PMID:1666497 PMID:1662895 PMID:1318680 |
|
definition |
A racemate comprising equimolar amounts of (R)- and (S)-temafloxacin. Both enantiomers both exhibit similar pharmacological profiles. Temafloxacin was briefly used (either as the free base or as the hydrochloride salt) as an antibacterial drug but was withdrawn worldwide in 1992 following reports of serious side effects, including severe hypoglycaemia, haemolytic anaemia, liver and kidney dysfunction, anaphylaxis, and death. |
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has part | ||
has role |
http://purl.obolibrary.org/obo/CHEBI_35441 |
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has_exact_synonym |
rac-1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
|
has_obo_namespace |
chebi_ontology |
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has_related_synonym |
(+-)-1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid temafloxacine temafloxacin temafloxacinum temafloxacino (+-)-temafloxacin rac-temafloxacin T 1258 A 62254 |
|
id |
CHEBI:77788 |
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in_subset | ||
label |
temafloxacin |
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notation |
CHEBI:77788 |
|
prefLabel |
temafloxacin |
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treeView | ||
subClassOf |