loading...| Preferred Name |
fluticasone furoate |
|
| Synonyms |
6alpha,9-difluoro-17beta-{[(fluoromethyl)sulfanyl]carbonyl}-11beta-hydroxy-16-methyl-3-oxoandrosta-1,4-dien-17alpha-yl 2-furoate Veramyst furoato de fluticasona furoate de fluticasone GSK 685698 fluticasonum furoas fluticasone furoate |
|
| Definitions |
A trifluorinated corticosteroid that consists of 6alpha,9-difluoro-11beta,17alpha-dihydroxy-17beta-{[(fluoromethyl)sulfanyl]carbonyl}-16-methyl-3-oxoandrosta-1,4-diene bearing a 2-furoyl substituent at position 17. Used in combination with vilanterol trifenate for treatment of bronchospasm associated with chronic obstructive pulmonary disease. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_74899 |
|
| charge |
0 |
|
| database_cross_reference |
PMID:23735179 PMID:21828231 PMID:23821392 PMID:22738148 Drug_Central:4554 Wikipedia:Fluticasone_furoate PMID:23352226 PMID:23440247 Reaxys:15686794 PMID:23116485 PMID:23332861 PMID:23184737 PMID:22391079 PMID:22387656 PMID:22342538 PMID:23719680 PMID:23018908 PMID:23846316 PMID:23806459 PMID:22170807 Patent:WO2011151624 Patent:WO2010016931 CAS:397864-44-7 Patent:WO2012160338 KEGG:D06315 PMID:23406601 PDBeChem:GW6 Patent:WO2011151625 PMID:23578031 PMID:23676578 Patent:US2009118495 PMID:22614920 PMID:23200625 PMID:23548539 |
|
| definition |
A trifluorinated corticosteroid that consists of 6alpha,9-difluoro-11beta,17alpha-dihydroxy-17beta-{[(fluoromethyl)sulfanyl]carbonyl}-16-methyl-3-oxoandrosta-1,4-diene bearing a 2-furoyl substituent at position 17. Used in combination with vilanterol trifenate for treatment of bronchospasm associated with chronic obstructive pulmonary disease. |
|
| formula |
C27H29F3O6S |
|
| has functional parent | ||
| has parent hydride | ||
| has role |
http://purl.obolibrary.org/obo/CHEBI_50266 |
|
| has_exact_synonym |
6alpha,9-difluoro-17beta-{[(fluoromethyl)sulfanyl]carbonyl}-11beta-hydroxy-16-methyl-3-oxoandrosta-1,4-dien-17alpha-yl 2-furoate |
|
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
Veramyst furoato de fluticasona furoate de fluticasone GSK 685698 fluticasonum furoas fluticasone furoate |
|
| id |
CHEBI:74899 |
|
| in_subset | ||
| inchi |
InChI=1S/C27H29F3O6S/c1-14-9-16-17-11-19(29)18-10-15(31)6-7-24(18,2)26(17,30)21(32)12-25(16,3)27(14,23(34)37-13-28)36-22(33)20-5-4-8-35-20/h4-8,10,14,16-17,19,21,32H,9,11-13H2,1-3H3/t14-,16+,17+,19+,21+,24+,25+,26+,27+/m1/s1 |
|
| inchikey |
XTULMSXFIHGYFS-VLSRWLAYSA-N |
|
| label |
fluticasone furoate |
|
| mass |
538.57600 |
|
| monoisotopicmass |
538.16369 |
|
| notation |
CHEBI:74899 |
|
| prefLabel |
fluticasone furoate |
|
| smiles |
[H][C@@]12C[C@@H](C)[C@](OC(=O)c3ccco3)(C(=O)SCF)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])C[C@H](F)C2=CC(=O)C=C[C@]12C |
|
| treeView |
http://purl.obolibrary.org/obo/CHEBI_47880 http://purl.obolibrary.org/obo/CHEBI_50858 http://purl.obolibrary.org/obo/CHEBI_51277 http://purl.obolibrary.org/obo/CHEBI_77166 http://purl.obolibrary.org/obo/CHEBI_50830 |
|
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_47880 http://purl.obolibrary.org/obo/CHEBI_50858 http://purl.obolibrary.org/obo/CHEBI_51277 http://purl.obolibrary.org/obo/CHEBI_77166 http://purl.obolibrary.org/obo/CHEBI_50830 |