loading...| Preferred Name |
loratadine |
|
| Synonyms |
ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate Allerclear 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic acid ethyl ester loratadina Alavert Wal-itin Civeran Claratyne Lorastine Loradamed Aerotina Alerpriv Loratyne Loracert Alarin loratadine loratadinum Claritin Loradex |
|
| Definitions |
A benzocycloheptapyridine that is 6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine substituted by a chloro group at position 8 and a 1-(ethoxycarbonyl)piperidin-4-ylidene group at position 11. It is a H1-receptor antagonist commonly employed in the treatment of allergic disorders. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_6538 |
|
| charge |
0 |
|
| database_cross_reference |
HMDB:HMDB0005000 PMID:31315424 DrugBank:DB00455 PMID:34121623 Reaxys:4273483 CAS:79794-75-5 FooDB:FDB023577 PMID:34306392 PMID:24134630 Chemspider:3820 PMID:33550204 PMID:7522069 PMID:15627436 PMID:33963858 PMID:32877950 PMID:33673552 LINCS:LSM-5891 PMID:32312261 Wikipedia:Loratadine KEGG:D00364 PMID:32694422 Drug_Central:1605 PMID:31576110 |
|
| definition |
A benzocycloheptapyridine that is 6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine substituted by a chloro group at position 8 and a 1-(ethoxycarbonyl)piperidin-4-ylidene group at position 11. It is a H1-receptor antagonist commonly employed in the treatment of allergic disorders. |
|
| formula |
C22H23ClN2O2 |
|
| has functional parent | ||
| has role |
http://purl.obolibrary.org/obo/CHEBI_37955 http://purl.obolibrary.org/obo/CHEBI_48873 |
|
| has_alternative_id |
CHEBI:94763 |
|
| has_exact_synonym |
ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate |
|
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
Allerclear 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic acid ethyl ester loratadina Alavert Wal-itin Civeran Claratyne Lorastine Loradamed Aerotina Alerpriv Loratyne Loracert Alarin loratadine loratadinum Claritin Loradex |
|
| id |
CHEBI:6538 |
|
| in_subset | ||
| inchi |
InChI=1S/C22H23ClN2O2/c1-2-27-22(26)25-12-9-15(10-13-25)20-19-8-7-18(23)14-17(19)6-5-16-4-3-11-24-21(16)20/h3-4,7-8,11,14H,2,5-6,9-10,12-13H2,1H3 |
|
| inchikey |
JCCNYMKQOSZNPW-UHFFFAOYSA-N |
|
| label |
loratadine |
|
| mass |
382.890 |
|
| monoisotopicmass |
382.14481 |
|
| notation |
CHEBI:6538 |
|
| prefLabel |
loratadine |
|
| smiles |
CCOC(=O)N1CCC(CC1)=C1C2=C(CCC3=C1N=CC=C3)C=C(Cl)C=C2 |
|
| treeView |
http://purl.obolibrary.org/obo/CHEBI_48593 http://purl.obolibrary.org/obo/CHEBI_140326 http://purl.obolibrary.org/obo/CHEBI_36683 |
|
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_48593 http://purl.obolibrary.org/obo/CHEBI_140326 http://purl.obolibrary.org/obo/CHEBI_36683 |