Preferred Name

nevirapine

Synonyms

11-cyclopropyl-4-methyl-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one

nevirapine

Nevirapine

NEV

NVP

Viramune

11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one

Definitions

A dipyridodiazepine that is 5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepine which is substituted by methyl, oxo, and cyclopropyl groups at positions 4, 6, and 11, respectively. A non-nucleoside reverse transcriptase inhibitor with activity against HIV-1, it is used in combination with other antiretrovirals for the treatment of HIV infection.

ID

http://purl.obolibrary.org/obo/CHEBI_63613

charge

0

database_cross_reference

Wikipedia:Nevirapine

PMID:28782122

PDBeChem:NVP

LINCS:LSM-5336

PMID:1712395

CAS:129618-40-2

KEGG:C07263

KEGG:D00435

PMID:28819312

PMID:28835669

DrugBank:DB00238

Reaxys:4757598

PMID:25017682

PMID:28786740

PMID:28827836

definition

A dipyridodiazepine that is 5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepine which is substituted by methyl, oxo, and cyclopropyl groups at positions 4, 6, and 11, respectively. A non-nucleoside reverse transcriptase inhibitor with activity against HIV-1, it is used in combination with other antiretrovirals for the treatment of HIV infection.

formula

C15H14N4O

has role

http://purl.obolibrary.org/obo/CHEBI_36044

http://purl.obolibrary.org/obo/CHEBI_53756

has_alternative_id

CHEBI:7546

has_exact_synonym

11-cyclopropyl-4-methyl-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one

Nevirapine

has_obo_namespace

chebi_ontology

has_related_synonym

nevirapine

NEV

NVP

Viramune

11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one

id

CHEBI:63613

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

inchi

InChI=1S/C15H14N4O/c1-9-6-8-17-14-12(9)18-15(20)11-3-2-7-16-13(11)19(14)10-4-5-10/h2-3,6-8,10H,4-5H2,1H3,(H,18,20)

inchikey

NQDJXKOVJZTUJA-UHFFFAOYSA-N

label

nevirapine

mass

266.29790

monoisotopicmass

266.11676

notation

CHEBI:63613

prefLabel

nevirapine

smiles

Cc1ccnc2N(C3CC3)c3ncccc3C(=O)Nc12

treeView

http://purl.obolibrary.org/obo/CHEBI_63667

http://purl.obolibrary.org/obo/CHEBI_51454

subClassOf

http://purl.obolibrary.org/obo/CHEBI_63667

http://purl.obolibrary.org/obo/CHEBI_51454

Delete Subject Author Type Created
No notes to display
Create New Mapping

Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/DRON_00018005 ODNAE LOOM
http://purl.obolibrary.org/obo/DRON_00018005 DRON LOOM
http://purl.obolibrary.org/obo/DRON_00018005 DRON LOOM
http://purl.obolibrary.org/obo/HIV_5661 HIV LOOM
http://stirdf.jst.go.jp/id/200907058603129480 IOBC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#16392 OCHV LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.725.506 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148461 NDFRT LOOM
http://purl.bioontology.org/ontology/CSP/4007-0088 CRISP LOOM
http://purl.bioontology.org/ontology/UATC/J05AG01 ATC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/386898005 SNOMEDCT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29277 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29277 NCIT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0132326 OCHV LOOM
http://purl.bioontology.org/ontology/LNC/LP21317-0 LOINC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU013861 LOINC LOOM
http://scai.fraunhofer.de/HuPSON#SCAIVPH_00001116 HUPSON LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D019829 RH-MESH LOOM
http://purl.jp/bio/4/id/200906087539392330 IOBC LOOM
http://purl.bioontology.org/ontology/VANDF/4020991 VANDF LOOM
http://purl.bioontology.org/ontology/RXNORM/53654 RXNORM LOOM
http://purl.bioontology.org/ontology/RCD/eiK.. RCD LOOM
http://purl.bioontology.org/ontology/MESH/D019829 MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_63613 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_63613 CCONT SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63613 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_63613 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63613 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_63613 DINTO SAME_URI
http://purl.bioontology.org/ontology/PDQ/CDR0000712787 PDQ LOOM
http://www.co-ode.org/ontologies/galen#Nevirapine GALEN LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000148461 ODAE LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0004478 FASTO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0004478 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0004478 DMTO LOOM