loading...| Preferred Name |
colistimethate |
|
| Synonyms |
|
|
| Definitions |
A mixture where R = H or Me. Colistin in which each of the primary amino groups is converted to the corresponding aminomethanesulfonic acid. It is prepared from colistin by the action of formaldehyde followed by sodium bisulfite. A polymyxin antibiotic, it is used as its penta-sodium salt in the treatment of severe infections, particularly of multidrug-resistant Gram-negative bacteria such as Pseudomonas aeruginosa and Acinetobacter baumannii. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_59662 |
|
| charge |
0 |
|
| database_cross_reference |
DrugBank:DB01111 PMID:16931410 |
|
| definition |
A mixture where R = H or Me. Colistin in which each of the primary amino groups is converted to the corresponding aminomethanesulfonic acid. It is prepared from colistin by the action of formaldehyde followed by sodium bisulfite. A polymyxin antibiotic, it is used as its penta-sodium salt in the treatment of severe infections, particularly of multidrug-resistant Gram-negative bacteria such as Pseudomonas aeruginosa and Acinetobacter baumannii. |
|
| formula |
C57H107N16O28S5R |
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| has functional parent | ||
| has part | ||
| has role | ||
| has_obo_namespace |
chebi_ontology |
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| id |
CHEBI:59662 |
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| in_subset | ||
| is conjugate acid of | ||
| label |
colistimethate |
|
| mass |
1624.883 |
|
| monoisotopicmass |
1623.60443 |
|
| notation |
CHEBI:59662 |
|
| prefLabel |
colistimethate |
|
| smiles |
C(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]1C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)NCC1)[C@@H](C)O)=O)CCNCS(O)(=O)=O)=O)CCNCS(O)(=O)=O)=O)CC(C)C)=O)CC(C)C)=O)CCNCS(O)(=O)=O)=O)=O)CCNCS(O)(=O)=O)=O)[C@@H](C)O)=O)CCNCS(O)(=O)=O)=O)CCC[C@@H](C*)C |
|
| treeView |
http://purl.obolibrary.org/obo/CHEBI_37793 |
|
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_37793 |