Preferred Name

gatifloxacin

Synonyms

gatifloxacinum

1-cyclopropyl-6-fluoro- 8-methoxy-7-(3-methylpiperazin-1-yl)- 4-oxo-quinoline-3-carboxylic acid

AM 1155

gatifloxacino

1-Cyclopropyl-1,4-dihydro-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid

gatifloxacin

gatifloxacine

1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Definitions

A monocarboxylic acid that is 4-oxo-1,4-dihydroquinoline-3-carboxylic acid which is substituted on the nitrogen by a cyclopropyl group and at positions 6, 7, and 8 by fluoro, 3-methylpiperazin-1-yl, and methoxy groups, respectively. Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial topoisomerase type-II enzymes.

ID

http://purl.obolibrary.org/obo/CHEBI_5280

charge

0

database_cross_reference

PMID:16078842

PMID:17043131

PMID:18078756

PMID:26963935

PMID:12873512

PMID:17387152

PMID:17276057

Patent:EP230295

PMID:16759086

CAS:112811-59-3

PMID:10737746

PMID:12904069

Drug_Central:1280

PMID:17325221

PMID:17043111

KEGG:C07661

PMID:17220425

PMID:17261623

PMID:17960928

PMID:16554151

PMID:17116668

PMID:7473575

PMID:12620077

Gmelin:2281206

Wikipedia:Gatifloxacin

Beilstein:7445861

PMID:17804222

PMID:17296740

PMID:17116666

Reaxys:7445861

DrugBank:DB01044

Patent:US4980470

PMID:17933535

PMID:15911273

PMID:17064062

PMID:16337791

PMID:18304818

LINCS:LSM-5139

PMID:12190308

KEGG:D08011

PMID:15125930

PMID:17157008

PMID:15745831

definition

A monocarboxylic acid that is 4-oxo-1,4-dihydroquinoline-3-carboxylic acid which is substituted on the nitrogen by a cyclopropyl group and at positions 6, 7, and 8 by fluoro, 3-methylpiperazin-1-yl, and methoxy groups, respectively. Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial topoisomerase type-II enzymes.

formula

C19H22FN3O4

has role

http://purl.obolibrary.org/obo/CHEBI_33281

http://purl.obolibrary.org/obo/CHEBI_50750

http://purl.obolibrary.org/obo/CHEBI_35441

has_alternative_id

CHEBI:101712

has_exact_synonym

1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

has_obo_namespace

chebi_ontology

has_related_synonym

gatifloxacinum

1-cyclopropyl-6-fluoro- 8-methoxy-7-(3-methylpiperazin-1-yl)- 4-oxo-quinoline-3-carboxylic acid

AM 1155

gatifloxacino

1-Cyclopropyl-1,4-dihydro-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid

gatifloxacin

gatifloxacine

id

CHEBI:5280

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

inchi

InChI=1S/C19H22FN3O4/c1-10-8-22(6-5-21-10)16-14(20)7-12-15(18(16)27-2)23(11-3-4-11)9-13(17(12)24)19(25)26/h7,9-11,21H,3-6,8H2,1-2H3,(H,25,26)

inchikey

XUBOMFCQGDBHNK-UHFFFAOYSA-N

label

gatifloxacin

mass

375.39410

monoisotopicmass

375.15943

notation

CHEBI:5280

prefLabel

gatifloxacin

smiles

COc1c(N2CCNC(C)C2)c(F)cc2c1n(cc(C(O)=O)c2=O)C1CC1

treeView

http://purl.obolibrary.org/obo/CHEBI_46848

http://purl.obolibrary.org/obo/CHEBI_26512

http://purl.obolibrary.org/obo/CHEBI_23765

http://purl.obolibrary.org/obo/CHEBI_37143

http://purl.obolibrary.org/obo/CHEBI_86324

subClassOf

http://purl.obolibrary.org/obo/CHEBI_46848

http://purl.obolibrary.org/obo/CHEBI_26512

http://purl.obolibrary.org/obo/CHEBI_23765

http://purl.obolibrary.org/obo/CHEBI_37143

http://purl.obolibrary.org/obo/CHEBI_86324

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