Preferred Name |
famciclovir |
|
Synonyms |
FAMCICLOVIR 2-[(acetyloxy)methyl]-4-(2-amino-9H-purin-9-yl)butyl acetate famciclovir acetic acid 2-acetoxymethyl-4-(2-amino-purin-9-yl)-butyl ester FCV 2-(2-(2-amino-9H-purin-9-yl)ethyl)-1,3-propanediol diacetate famciclovirum 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine Famvir BRL-42810 |
|
Definitions |
2-Amino-9H-purine in which the hydrogen at position 9 is substituted by a 4-acetoxy-3-(acetoxymethyl)but-1-yl group. A prodrug of the antiviral penciclovir, it is used for the treatment of acute herpes zoster (shingles), for the treatment or suppression of recurrent genital herpes in immunocompetent patients and for the treatment of recurrent mucocutaneous herpes simplex infections in HIV infected patients. |
|
ID |
http://purl.obolibrary.org/obo/CHEBI_4974 |
|
charge |
0 |
|
database_cross_reference |
Reaxys:4208403 PMID:9719596 Drug_Central:1128 Wikipedia:Famciclovir CAS:104227-87-4 Patent:US5246937 DrugBank:DB00426 HMDB:HMDB0014570 PMID:17870541 PMID:2754699 LINCS:LSM-2990 KEGG:D00317 |
|
definition |
2-Amino-9H-purine in which the hydrogen at position 9 is substituted by a 4-acetoxy-3-(acetoxymethyl)but-1-yl group. A prodrug of the antiviral penciclovir, it is used for the treatment of acute herpes zoster (shingles), for the treatment or suppression of recurrent genital herpes in immunocompetent patients and for the treatment of recurrent mucocutaneous herpes simplex infections in HIV infected patients. |
|
formula |
C14H19N5O4 |
|
has role | ||
has_alternative_id |
CHEBI:174284 |
|
has_exact_synonym |
FAMCICLOVIR 2-[(acetyloxy)methyl]-4-(2-amino-9H-purin-9-yl)butyl acetate |
|
has_obo_namespace |
chebi_ontology |
|
has_related_synonym |
famciclovir acetic acid 2-acetoxymethyl-4-(2-amino-purin-9-yl)-butyl ester FCV 2-(2-(2-amino-9H-purin-9-yl)ethyl)-1,3-propanediol diacetate famciclovirum 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine Famvir BRL-42810 |
|
id |
CHEBI:4974 |
|
in_subset | ||
inchi |
InChI=1S/C14H19N5O4/c1-9(20)22-6-11(7-23-10(2)21)3-4-19-8-17-12-5-16-14(15)18-13(12)19/h5,8,11H,3-4,6-7H2,1-2H3,(H2,15,16,18) |
|
inchikey |
GGXKWVWZWMLJEH-UHFFFAOYSA-N |
|
label |
famciclovir |
|
mass |
321.33180 |
|
monoisotopicmass |
321.14370 |
|
notation |
CHEBI:4974 |
|
prefLabel |
famciclovir |
|
smiles |
CC(=O)OCC(CCn1cnc2cnc(N)nc12)COC(C)=O |
|
treeView | ||
subClassOf |