Preferred Name

pentamidine

Synonyms

1,5-bis(4-amidinophenoxy)pentane

pentamidine

4,4'-(1,5-pentanediylbis(oxy))bis-benzenecarboximidamide

4,4'-(pentamethylenedioxy)dibenzamidine

4,4'-Diamidinodiphenoxypentane

pentamidin

4,4'-[pentane-1,5-diylbis(oxy)]dibenzenecarboximidamide

Pentamidine

p,p'-(pentamethylenedioxy)dibenzamidine

Definitions

A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.

ID

http://purl.obolibrary.org/obo/CHEBI_45081

charge

0

database_cross_reference

Beilstein:3159790

PMID:27011917

PMID:7690919

PMID:27357655

Patent:EP975608

PMID:20144237

PMID:28167598

PMID:22327112

PMID:26418240

Patent:US2394003

PMID:11584934

PMID:26903605

Patent:GB507565

PMID:26824946

HMDB:HMDB0014876

PMID:26052915

PMID:26117647

PMID:18346045

PMID:26606757

PMID:10917591

Patent:US2008214569

PMID:11438428

PMID:14603035

Wikipedia:Pentamidine

PMID:26938448

LINCS:LSM-4540

PMID:18971316

Reaxys:3159790

Patent:US7115665

PMID:15711592

PMID:27297108

Patent:US2008167296

PDBeChem:PNT

PMID:27164533

PMID:22046004

PMID:8841838

PMID:26431253

KEGG:C07420

PMID:27135970

PMID:26344166

PMID:26828608

PMID:7542607

PMID:20599360

CAS:100-33-4

PMID:27729250

PMID:28263303

PMID:28074607

PMID:26515653

PMID:26295040

Patent:US2006235001

PMID:26882015

PMID:27214074

PMID:22093811

PMID:26648589

Drug_Central:2090

PMID:27600039

PMID:19966562

KEGG:D08333

PMID:26734860

PMID:27353022

PMID:10415905

DrugBank:DB00738

PMID:22200378

definition

A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.

formula

C19H24N4O2

has role

http://purl.obolibrary.org/obo/CHEBI_35703

http://purl.obolibrary.org/obo/CHEBI_76395

http://purl.obolibrary.org/obo/CHEBI_63673

http://purl.obolibrary.org/obo/CHEBI_36335

http://purl.obolibrary.org/obo/CHEBI_136651

http://purl.obolibrary.org/obo/CHEBI_60643

http://purl.obolibrary.org/obo/CHEBI_130181

http://purl.obolibrary.org/obo/CHEBI_35718

http://purl.obolibrary.org/obo/CHEBI_67079

has_alternative_id

CHEBI:45077

CHEBI:7976

has_exact_synonym

4,4'-[pentane-1,5-diylbis(oxy)]dibenzenecarboximidamide

Pentamidine

has_obo_namespace

chebi_ontology

has_related_synonym

1,5-bis(4-amidinophenoxy)pentane

pentamidine

4,4'-(1,5-pentanediylbis(oxy))bis-benzenecarboximidamide

4,4'-(pentamethylenedioxy)dibenzamidine

4,4'-Diamidinodiphenoxypentane

pentamidin

p,p'-(pentamethylenedioxy)dibenzamidine

id

CHEBI:45081

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

inchi

InChI=1S/C19H24N4O2/c20-18(21)14-4-8-16(9-5-14)24-12-2-1-3-13-25-17-10-6-15(7-11-17)19(22)23/h4-11H,1-3,12-13H2,(H3,20,21)(H3,22,23)

inchikey

XDRYMKDFEDOLFX-UHFFFAOYSA-N

is conjugate base of

http://purl.obolibrary.org/obo/CHEBI_64383

label

pentamidine

mass

340.420

monoisotopicmass

340.18993

notation

CHEBI:45081

prefLabel

pentamidine

smiles

C(CCCOC1=CC=C(C=C1)C(N)=N)COC2=CC=C(C=C2)C(N)=N

treeView

http://purl.obolibrary.org/obo/CHEBI_35618

http://purl.obolibrary.org/obo/CHEBI_35359

http://purl.obolibrary.org/obo/CHEBI_46786

subClassOf

http://purl.obolibrary.org/obo/CHEBI_35618

http://purl.obolibrary.org/obo/CHEBI_35359

http://purl.obolibrary.org/obo/CHEBI_46786

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