Preferred Name

dezocine

Synonyms

(5R,11S,13S)-13-amino-5-methyl-5,6,7,8,9,10,11,12-octahydro-5,11-methanobenzocyclodecen-3-ol

dezocine

dezocinum

dezocina

Dezocine

(-)-13beta-amino-5,6,7,8,9,10,11alpha,12-octahydro-5alpha-methyl-5,11-methanobenzocyclodecen-3-ol

Definitions

(7S,8S)-7-Amino-8-methyl-5,6,7,8-tetrahydronaphthalen-2-ol in which the hydrogen at position 8 and one of the hydrogens at position 6 are substituted by each end of a tetramethylene bridge. A synthetic opioid analgesic, it has mixed opiod agonist and antagonist properties. Although it is used for pain management, it can produce opioid withdrawal syndrome in patients already dependent on other opioids, and its clinical application is limited by side effects such as dizziness.

ID

http://purl.obolibrary.org/obo/CHEBI_4474

charge

0

database_cross_reference

DrugBank:DB01209

CAS:53648-55-8

Drug_Central:847

KEGG:D00838

Patent:DE2159324

Wikipedia:Dezocine

KEGG:C08010

Beilstein:3033759

definition

(7S,8S)-7-Amino-8-methyl-5,6,7,8-tetrahydronaphthalen-2-ol in which the hydrogen at position 8 and one of the hydrogens at position 6 are substituted by each end of a tetramethylene bridge. A synthetic opioid analgesic, it has mixed opiod agonist and antagonist properties. Although it is used for pain management, it can produce opioid withdrawal syndrome in patients already dependent on other opioids, and its clinical application is limited by side effects such as dizziness.

formula

C16H23NO

has role

http://purl.obolibrary.org/obo/CHEBI_35482

has_alternative_id

CHEBI:618361

has_exact_synonym

(5R,11S,13S)-13-amino-5-methyl-5,6,7,8,9,10,11,12-octahydro-5,11-methanobenzocyclodecen-3-ol

Dezocine

has_obo_namespace

chebi_ontology

has_related_synonym

dezocine

dezocinum

dezocina

(-)-13beta-amino-5,6,7,8,9,10,11alpha,12-octahydro-5alpha-methyl-5,11-methanobenzocyclodecen-3-ol

id

CHEBI:4474

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

inchi

InChI=1S/C16H23NO/c1-16-8-4-2-3-5-12(15(16)17)9-11-6-7-13(18)10-14(11)16/h6-7,10,12,15,18H,2-5,8-9,17H2,1H3/t12-,15-,16+/m0/s1

inchikey

VTMVHDZWSFQSQP-VBNZEHGJSA-N

label

dezocine

mass

245.35990

monoisotopicmass

245.17796

notation

CHEBI:4474

prefLabel

dezocine

smiles

[H][C@@]12CCCCC[C@@](C)([C@H]1N)c1cc(O)ccc1C2

treeView

http://purl.obolibrary.org/obo/CHEBI_50994

http://purl.obolibrary.org/obo/CHEBI_33853

subClassOf

http://purl.obolibrary.org/obo/CHEBI_50994

http://purl.obolibrary.org/obo/CHEBI_33853

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http://www.drugbank.ca/drugs/DB01209 FTC LOOM
http://purl.obolibrary.org/obo/CHEBI_4474 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_4474 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4474 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_4474 DINTO SAME_URI
http://purl.bioontology.org/ontology/LNC/LP18550-1 LOINC LOOM
http://stirdf.jst.go.jp/id/200907019842073831 IOBC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147635 NDFRT LOOM
http://purl.bioontology.org/ontology/NDDF/003545 NDDF LOOM
http://purl.bioontology.org/ontology/VANDF/4019515 VANDF LOOM
http://purl.bioontology.org/ontology/MESH/C010827 MESH LOOM
http://purl.bioontology.org/ontology/LNC/MTHU004622 LOINC LOOM
http://purl.jp/bio/4/id/200906029605163216 IOBC LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65374 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65374 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65374 NCIT LOOM
http://purl.obolibrary.org/obo/DRON_00010596 DRON LOOM
http://purl.bioontology.org/ontology/UATC/N02AX03 ATC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/108377005 SNOMEDCT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C010827 RH-MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/22713 RXNORM LOOM