Preferred Name

desmopressin

Synonyms

1-{[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-prolyl-D-arginylglycinamide

1-deamino-8-D-arginine vasopressin

desmopressinum

desmopressin

DDAVP

1-(3-mercaptopropionic acid)-8-D-arginine-vasopressin

desmopressine

desmopresina

1-desamino-8-D-arginine vasopressin

Definitions

A synthetic analogue of vasopressin in which 3-mercaptopropionic acid replaces the cysteine residue at position 1 and D-arginine replaces the residue at position 8. An antidiuretic, it increases urine concentration and decreases urine production, and is used (usually as the trihydrate of the acetic acid salt) to prevent and control excessive thirst, urination, and dehydration caused by injury, surgery, and certain medical conditions. It is also used in the diagnosis and treatment of cranial diabetes insipidus and in tests of renal function.

ID

http://purl.obolibrary.org/obo/CHEBI_4450

charge

0

database_cross_reference

KEGG:C06944

KEGG:D00291

CAS:16679-58-6

DrugBank:DB00035

Beilstein:4651966

Drug_Central:817

definition

A synthetic analogue of vasopressin in which 3-mercaptopropionic acid replaces the cysteine residue at position 1 and D-arginine replaces the residue at position 8. An antidiuretic, it increases urine concentration and decreases urine production, and is used (usually as the trihydrate of the acetic acid salt) to prevent and control excessive thirst, urination, and dehydration caused by injury, surgery, and certain medical conditions. It is also used in the diagnosis and treatment of cranial diabetes insipidus and in tests of renal function.

formula

C46H64N14O12S2

has role

http://purl.obolibrary.org/obo/CHEBI_33295

http://purl.obolibrary.org/obo/CHEBI_35846

http://purl.obolibrary.org/obo/CHEBI_59727

has_exact_synonym

1-{[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-prolyl-D-arginylglycinamide

has_obo_namespace

chebi_ontology

has_related_synonym

1-deamino-8-D-arginine vasopressin

desmopressinum

desmopressin

DDAVP

1-(3-mercaptopropionic acid)-8-D-arginine-vasopressin

desmopressine

desmopresina

1-desamino-8-D-arginine vasopressin

id

CHEBI:4450

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

inchi

InChI=1S/C46H64N14O12S2/c47-35(62)15-14-29-40(67)58-32(22-36(48)63)43(70)59-33(45(72)60-18-5-9-34(60)44(71)56-28(8-4-17-52-46(50)51)39(66)53-23-37(49)64)24-74-73-19-16-38(65)54-30(21-26-10-12-27(61)13-11-26)41(68)57-31(42(69)55-29)20-25-6-2-1-3-7-25/h1-3,6-7,10-13,28-34,61H,4-5,8-9,14-24H2,(H2,47,62)(H2,48,63)(H2,49,64)(H,53,66)(H,54,65)(H,55,69)(H,56,71)(H,57,68)(H,58,67)(H,59,70)(H4,50,51,52)/t28-,29+,30+,31+,32+,33+,34+/m1/s1

inchikey

NFLWUMRGJYTJIN-PNIOQBSNSA-N

label

desmopressin

mass

1069.21700

monoisotopicmass

1068.42696

notation

CHEBI:4450

prefLabel

desmopressin

smiles

NC(=N)NCCC[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CSSCCC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)NCC(N)=O

treeView

http://purl.obolibrary.org/obo/CHEBI_24533

subClassOf

http://purl.obolibrary.org/obo/CHEBI_24533

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/HIO_0000191 HIO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147801 NDFRT LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/126189002 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/VANDF/4019709 VANDF LOOM
http://www.semanticweb.org/ontologies/2010/10/BPO.owl#desmopressin BHO LOOM
http://purl.bioontology.org/ontology/UATC/H01BA02 ATC LOOM
http://www.drugbank.ca/drugs/DB00035 FTC LOOM
http://stirdf.jst.go.jp/id/200907021677428390 IOBC LOOM
http://purl.bioontology.org/ontology/RXNORM/3251 RXNORM LOOM
http://purl.obolibrary.org/obo/CHEBI_4450 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_4450 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4450 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_4450 DINTO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4450 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_4450 DRON SAME_URI
http://www.co-ode.org/ontologies/galen#Desmopressin GALEN LOOM
http://purl.jp/bio/4/id/200906042339917311 IOBC LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61701 NCIT LOOM
http://purl.bioontology.org/ontology/NDDF/004784 NDDF LOOM
http://id.loc.gov/authorities/subjects/sh93001848 FAST-TOPICAL LOOM