Preferred Name

dexamethasone

Synonyms

1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone

dexametasona

dexamethasone

dexamethasonum

9alpha-Fluoro-16alpha-methylprednisolone

Dexamethasone

Decadron

16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol

9-fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione

Definitions

A fluorinated steroid that is 9-fluoropregna-1,4-diene substituted by hydroxy groups at positions 11, 17 and 21, a methyl group at position 16 and oxo groups at positions 3 and 20. It is a synthetic member of the class of glucocorticoids.

ID

http://purl.obolibrary.org/obo/CHEBI_41879

charge

0

database_cross_reference

PMID:18272184

CAS:50-02-2

VSDB:1769

KEGG:D00292

Reaxys:2066652

Patent:GB869511

Beilstein:2066652

PMID:18524938

Patent:DE1113690

Patent:US3007923

PMID:11508649

Drug_Central:824

KEGG:C15643

Wikipedia:Dexamethasone

DrugBank:DB01234

HMDB:HMDB0015364

definition

A fluorinated steroid that is 9-fluoropregna-1,4-diene substituted by hydroxy groups at positions 11, 17 and 21, a methyl group at position 16 and oxo groups at positions 3 and 20. It is a synthetic member of the class of glucocorticoids.

formula

C22H29FO5

has parent hydride

http://purl.obolibrary.org/obo/CHEBI_8386

has role

http://purl.obolibrary.org/obo/CHEBI_35703

http://purl.obolibrary.org/obo/CHEBI_50919

http://purl.obolibrary.org/obo/CHEBI_35705

http://purl.obolibrary.org/obo/CHEBI_35610

http://purl.obolibrary.org/obo/CHEBI_78298

http://purl.obolibrary.org/obo/CHEBI_35472

http://purl.obolibrary.org/obo/CHEBI_37962

has_alternative_id

CHEBI:4461

CHEBI:41873

has_exact_synonym

dexamethasone

Dexamethasone

9-fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione

has_obo_namespace

chebi_ontology

has_related_synonym

1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone

dexametasona

dexamethasone

dexamethasonum

9alpha-Fluoro-16alpha-methylprednisolone

Decadron

16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol

id

CHEBI:41879

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

inchi

InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1

inchikey

UREBDLICKHMUKA-CXSFZGCWSA-N

label

dexamethasone

mass

392.46106

monoisotopicmass

392.19990

notation

CHEBI:41879

prefLabel

dexamethasone

smiles

[H][C@@]12C[C@@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C

treeView

http://purl.obolibrary.org/obo/CHEBI_35346

http://purl.obolibrary.org/obo/CHEBI_77166

http://purl.obolibrary.org/obo/CHEBI_24261

http://purl.obolibrary.org/obo/CHEBI_35342

http://purl.obolibrary.org/obo/CHEBI_35344

http://purl.obolibrary.org/obo/CHEBI_50830

http://purl.obolibrary.org/obo/CHEBI_36885

subClassOf

http://purl.obolibrary.org/obo/CHEBI_35346

http://purl.obolibrary.org/obo/CHEBI_77166

http://purl.obolibrary.org/obo/CHEBI_24261

http://purl.obolibrary.org/obo/CHEBI_35342

http://purl.obolibrary.org/obo/CHEBI_35344

http://purl.obolibrary.org/obo/CHEBI_50830

http://purl.obolibrary.org/obo/CHEBI_36885

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