Preferred Name

clemastine

Synonyms

(2R)-2-{2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl}-1-methylpyrrolidine

Clemastine

clemastinum

clemastine

clemastina

(+)-(2R)-2-(2-(((R)-p-chloro-alpha-methyl-alpha-phenylbenzyl)oxy)ethyl)-1-methylpyrrolidine

(+)-(2R)-2-[2-[[(R)-p-chloro-alpha-methyl-alpha-phenylbenzyl]oxy]ethyl]-1-methylpyrrolidine

Definitions

2-[(2R)-1-Methylpyrrolidin-2-yl]ethanol in which the hydrogen of the hydroxy group is substituted by a 1-(4-chlorophenyl)-1-phenylethyl group (R configuration). An antihistamine with antimuscarinic and moderate sedative properties, it is used as its fumarate salt for the symptomatic relief of allergic conditions such as rhinitis, urticaria, conjunctivitis and in pruritic (severe itching) skin conditions.

ID

http://purl.obolibrary.org/obo/CHEBI_3738

charge

0

database_cross_reference

Beilstein:6486432

DrugBank:DB00283

Patent:GB942152

CAS:15686-51-8

Drug_Central:671

PMID:18788725

Wikipedia:Clemastine

LINCS:LSM-2655

KEGG:C06913

KEGG:D03535

definition

2-[(2R)-1-Methylpyrrolidin-2-yl]ethanol in which the hydrogen of the hydroxy group is substituted by a 1-(4-chlorophenyl)-1-phenylethyl group (R configuration). An antihistamine with antimuscarinic and moderate sedative properties, it is used as its fumarate salt for the symptomatic relief of allergic conditions such as rhinitis, urticaria, conjunctivitis and in pruritic (severe itching) skin conditions.

formula

C21H26ClNO

has role

http://purl.obolibrary.org/obo/CHEBI_37955

http://purl.obolibrary.org/obo/CHEBI_48876

http://purl.obolibrary.org/obo/CHEBI_59683

http://purl.obolibrary.org/obo/CHEBI_50857

has_alternative_id

CHEBI:569763

has_exact_synonym

(2R)-2-{2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl}-1-methylpyrrolidine

Clemastine

has_obo_namespace

chebi_ontology

has_related_synonym

clemastinum

clemastine

clemastina

(+)-(2R)-2-(2-(((R)-p-chloro-alpha-methyl-alpha-phenylbenzyl)oxy)ethyl)-1-methylpyrrolidine

(+)-(2R)-2-[2-[[(R)-p-chloro-alpha-methyl-alpha-phenylbenzyl]oxy]ethyl]-1-methylpyrrolidine

id

CHEBI:3738

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

inchi

InChI=1S/C21H26ClNO/c1-21(17-7-4-3-5-8-17,18-10-12-19(22)13-11-18)24-16-14-20-9-6-15-23(20)2/h3-5,7-8,10-13,20H,6,9,14-16H2,1-2H3/t20-,21-/m1/s1

inchikey

YNNUSGIPVFPVBX-NHCUHLMSSA-N

label

clemastine

mass

343.89000

monoisotopicmass

343.17029

notation

CHEBI:3738

prefLabel

clemastine

smiles

[H][C@@]1(CCCN1C)CCO[C@](C)(c1ccccc1)c1ccc(Cl)cc1

treeView

http://purl.obolibrary.org/obo/CHEBI_83403

http://purl.obolibrary.org/obo/CHEBI_46775

subClassOf

http://purl.obolibrary.org/obo/CHEBI_83403

http://purl.obolibrary.org/obo/CHEBI_46775

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_3738 PDRO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3738 FIDEO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3738 DINTO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3738 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3738 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3738 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3738 CIDO SAME_URI
http://www.co-ode.org/ontologies/galen#Clemastine GALEN LOOM
http://purl.obolibrary.org/obo/NCIT_C61682 BERO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372744005 SNOMEDCT LOOM
https://go.drugbank.com/drugs/DB00283 MDM LOOM
http://purl.bioontology.org/ontology/ATC/R06AA04 ATC LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61682 NCIT LOOM
http://purl.bioontology.org/ontology/RXNORM/2578 RXNORM LOOM
http://purl.bioontology.org/ontology/NDDF/004441 NDDF LOOM
http://purl.obolibrary.org/obo/MESH_D002974 BERO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0008929 OCHV LOOM
http://purl.obolibrary.org/obo/OMIT_0004289 OMIT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.773.165 RH-MESH LOOM
http://www.phoc.org.cn/pmo/class/PMO_00018472 PMAPP-PMO LOOM
http://purl.obolibrary.org/obo/CHEBI_3738 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_3738 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_3738 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_3738 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_3738 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_3738 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_3738 CIDO LOOM
http://purl.bioontology.org/ontology/ATC/D04AA14 ATC LOOM
http://www.drugbank.ca/drugs/DB00283 FTC LOOM
http://purl.bioontology.org/ontology/RCD/c85.. RCD LOOM
http://purl.bioontology.org/ontology/SNMI/C-51440 SNMI LOOM
http://purl.jp/bio/4/id/200906088282953430 IOBC LOOM
http://purl.bioontology.org/ontology/VANDF/4019681 VANDF LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#3029 OCHV LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D002974 RH-MESH LOOM
http://purl.bioontology.org/ontology/MESH/D002974 MESH LOOM
http://stirdf.jst.go.jp/id/200907023463507783 IOBC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147773 NDFRT LOOM