loading...| Preferred Name |
amlodipine |
|
| Synonyms |
3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate amlodipinum amlodipino 3-Ethyl-5-methyl (+-)-2-(2-aminoethoxymethyl)-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate amlodipine Amlodipine Free Base |
|
| Definitions |
A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_2668 |
|
| charge |
0 |
|
| database_cross_reference |
VSDB:2963 PMID:21591999 Wikipedia:Amlodipine PMID:19450066 KEGG:D07450 PMID:8310972 PMID:16422032 Reaxys:3570229 Patent:US4572909 Drug_Central:183 Beilstein:3570229 PMID:1532771 PMID:8310973 LINCS:LSM-1388 PMID:7522286 KEGG:C06825 Patent:EP89167 CAS:88150-42-9 PMID:9156957 DrugBank:DB00381 PMID:1834846 |
|
| definition |
A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina. |
|
| formula |
C20H25ClN2O5 |
|
| has role |
http://purl.obolibrary.org/obo/CHEBI_35620 |
|
| has_exact_synonym |
3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate |
|
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
amlodipinum amlodipino 3-Ethyl-5-methyl (+-)-2-(2-aminoethoxymethyl)-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate amlodipine Amlodipine Free Base |
|
| id |
CHEBI:2668 |
|
| in_subset | ||
| inchi |
InChI=1S/C20H25ClN2O5/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h5-8,17,23H,4,9-11,22H2,1-3H3 |
|
| inchikey |
HTIQEAQVCYTUBX-UHFFFAOYSA-N |
|
| label |
amlodipine |
|
| mass |
408.87600 |
|
| monoisotopicmass |
408.14520 |
|
| notation |
CHEBI:2668 |
|
| prefLabel |
amlodipine |
|
| smiles |
CCOC(=O)C1=C(COCCN)NC(C)=C(C1c1ccccc1Cl)C(=O)OC |
|
| treeView |
http://purl.obolibrary.org/obo/CHEBI_83403 http://purl.obolibrary.org/obo/CHEBI_50075 http://purl.obolibrary.org/obo/CHEBI_50994 |
|
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_83403 http://purl.obolibrary.org/obo/CHEBI_50075 http://purl.obolibrary.org/obo/CHEBI_50994 |