Preferred Name

amifostine

Synonyms

Amifostine

S-{2-[(3-aminopropyl)amino]ethyl} dihydrogen thiophosphate

amifostina

amifostine

amifostinum

Ethyol

Definitions

An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.

ID

http://purl.obolibrary.org/obo/CHEBI_2636

charge

0

database_cross_reference

PMID:15875769

PMID:22878481

PMID:22885239

PMID:11201306

PMID:21347716

PMID:22844290

PMID:22440042

Beilstein:2088122

PMID:22402174

Wikipedia:Amifostine

PMID:12499421

PMID:23401928

PMID:17602063

Drug_Central:156

PMID:23040218

PMID:12433814

PMID:15698860

PMID:8612469

PMID:12005544

PMID:12751907

KEGG:C06819

PMID:8683243

PMID:21646919

PMID:10942928

Patent:US3892824

PMID:10553165

PMID:12561384

LINCS:LSM-4721

PMID:23092832

PMID:22456378

PMID:11984063

PMID:14980067

Reaxys:2088122

PMID:11013273

DrugBank:DB01143

PMID:19712749

PMID:20334641

CAS:20537-88-6

PMID:23052919

PMID:22496587

PMID:18072151

PMID:22267539

PMID:16465691

HMDB:HMDB0015274

PMID:22989457

PMID:22643562

PMID:18549666

PMID:15380592

definition

An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.

formula

C5H15N2O3PS

has functional parent

http://purl.obolibrary.org/obo/CHEBI_17141

has role

http://purl.obolibrary.org/obo/CHEBI_22586

http://purl.obolibrary.org/obo/CHEBI_66987

http://purl.obolibrary.org/obo/CHEBI_50266

has_exact_synonym

Amifostine

S-{2-[(3-aminopropyl)amino]ethyl} dihydrogen thiophosphate

has_obo_namespace

chebi_ontology

has_related_synonym

amifostina

amifostine

amifostinum

Ethyol

id

CHEBI:2636

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

inchi

InChI=1S/C5H15N2O3PS/c6-2-1-3-7-4-5-12-11(8,9)10/h7H,1-6H2,(H2,8,9,10)

inchikey

JKOQGQFVAUAYPM-UHFFFAOYSA-N

label

amifostine

mass

214.22404

monoisotopicmass

214.05410

notation

CHEBI:2636

prefLabel

amifostine

smiles

NCCCNCCSP(O)(O)=O

treeView

http://purl.obolibrary.org/obo/CHEBI_37512

http://purl.obolibrary.org/obo/CHEBI_23666

subClassOf

http://purl.obolibrary.org/obo/CHEBI_37512

http://purl.obolibrary.org/obo/CHEBI_23666

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Create mapping

Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_2636 PDRO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2636 DINTO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2636 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2636 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2636 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2636 NIFSTD SAME_URI
http://purl.bioontology.org/ontology/NDFRT/N0000148443 NDFRT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C488 NCIT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D004999 RH-MESH LOOM
http://purl.bioontology.org/ontology/ATC/V03AF05 ATC LOOM
http://purl.bioontology.org/ontology/RCD/h95.. RCD LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000039741 PDQ LOOM
http://purl.jp/bio/4/id/200906085160389070 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.705.400.625.050 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.300.692.050 RH-MESH LOOM
http://purl.obolibrary.org/obo/OMIT_0006228 OMIT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.705.539.345.050 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0015020 OCHV LOOM
http://purl.bioontology.org/ontology/MESH/D004999 MESH LOOM
http://purl.bioontology.org/ontology/VANDF/4020970 VANDF LOOM
http://www.drugbank.ca/drugs/DB01143 FTC LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017307 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/NDDF/005536 NDDF LOOM
http://purl.bioontology.org/ontology/RXNORM/4126 RXNORM LOOM
http://www.co-ode.org/ontologies/galen#Amifostine GALEN LOOM
http://stirdf.jst.go.jp/id/200907083247191839 IOBC LOOM
http://purl.obolibrary.org/obo/CHEBI_2636 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_2636 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_2636 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_2636 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_2636 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_2636 NIFSTD LOOM
http://purl.obolibrary.org/obo/NCIT_C488 BERO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/386923005 SNOMEDCT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#4699 OCHV LOOM
https://go.drugbank.com/drugs/DB01143 MDM LOOM
http://purl.obolibrary.org/obo/MESH_D004999 BERO LOOM