Preferred Name |
bromfenac |
|
Synonyms |
[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid 2-amino-3-(4-bromobenzoyl)benzeneacetic acid bromfenaco bromfenac bromfenacum [2-Amino-3-(4-bromo-benzoyl)-phenyl]-acetic acid |
|
Definitions |
Amfenac in which the the hydrogen at the 4 position of the benzoyl group is substituted by bromine. It is used for the management of ocular pain and treatment of postoperative inflammation in patients who have undergone cataract extraction. It was withdrawn from the US market in 1998, following concerns over off-label abuse and hepatic failure. |
|
ID |
http://purl.obolibrary.org/obo/CHEBI_240107 |
|
charge |
0 |
|
database_cross_reference |
Wikipedia:Bromfenac KEGG:D07541 DrugBank:DB00963 Drug_Central:401 LINCS:LSM-5585 Patent:US4683242 Patent:EP221753 Beilstein:8335547 CAS:91714-94-2 |
|
definition |
Amfenac in which the the hydrogen at the 4 position of the benzoyl group is substituted by bromine. It is used for the management of ocular pain and treatment of postoperative inflammation in patients who have undergone cataract extraction. It was withdrawn from the US market in 1998, following concerns over off-label abuse and hepatic failure. |
|
formula |
C15H12BrNO3 |
|
has functional parent | ||
has role | ||
has_exact_synonym |
[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid |
|
has_obo_namespace |
chebi_ontology |
|
has_related_synonym |
2-amino-3-(4-bromobenzoyl)benzeneacetic acid bromfenaco bromfenac bromfenacum [2-Amino-3-(4-bromo-benzoyl)-phenyl]-acetic acid |
|
id |
CHEBI:240107 |
|
in_subset | ||
inchi |
InChI=1S/C15H12BrNO3/c16-11-6-4-9(5-7-11)15(20)12-3-1-2-10(14(12)17)8-13(18)19/h1-7H,8,17H2,(H,18,19) |
|
inchikey |
ZBPLOVFIXSTCRZ-UHFFFAOYSA-N |
|
is conjugate acid of | ||
label |
bromfenac |
|
mass |
334.16500 |
|
monoisotopicmass |
333.00006 |
|
notation |
CHEBI:240107 |
|
prefLabel |
bromfenac |
|
smiles |
Nc1c(CC(O)=O)cccc1C(=O)c1ccc(Br)cc1 |
|
treeView |
http://purl.obolibrary.org/obo/CHEBI_33856 http://purl.obolibrary.org/obo/CHEBI_37141 |
|
subClassOf |
http://purl.obolibrary.org/obo/CHEBI_33856 http://purl.obolibrary.org/obo/CHEBI_37141 |