loading...| Preferred Name |
nalidixic acid |
|
| Synonyms |
Nalidixic acid NALIDIXIC ACID 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid 1,4-dihydro-1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid acidum nalidixicum 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid acido nalidixico nalidixic acid acide nalidixique 1-Aethyl-7-methyl-1,8-naphthyridin-4-on-3-karbonsaeure 1-ethyl-7-methyl-1,4-dihydro-1,8-naphthyridin-4-one-3-carboxylic acid 1-Ethyl-7-methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid 3-carboxy-1-ethyl-7-methyl-1,8-naphthyridin-4-one |
|
| Definitions |
A monocarboxylic acid comprising 1,8-naphthyridin-4-one substituted by carboxylic acid, ethyl and methyl groups at positions 3, 1, and 7, respectively. An orally administered antibacterial, it is used in the treatment of lower urinary-tract infections due to Gram-negative bacteria, including the majority of E. coli, Enterobacter, Klebsiella, and Proteus species. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_100147 |
|
| charge |
0 |
|
| database_cross_reference |
PMID:19071706 Patent:US3590036 Reaxys:750515 Patent:BE612258 PMID:28166217 Wikipedia:Nalidixic_Acid PMID:17631104 PMID:16803589 KEGG:C05079 PMID:16667857 VSDB:1880 PMID:17132068 PMID:16423473 PMID:16107187 PDBeChem:NIX PMID:18788798 PMID:12702698 PMID:12399485 CAS:389-08-2 LINCS:LSM-5590 PMID:11321869 PMID:12002106 DrugBank:DB00779 PMID:14107587 KEGG:D00183 Drug_Central:1875 |
|
| definition |
A monocarboxylic acid comprising 1,8-naphthyridin-4-one substituted by carboxylic acid, ethyl and methyl groups at positions 3, 1, and 7, respectively. An orally administered antibacterial, it is used in the treatment of lower urinary-tract infections due to Gram-negative bacteria, including the majority of E. coli, Enterobacter, Klebsiella, and Proteus species. |
|
| formula |
C12H12N2O3 |
|
| has role |
http://purl.obolibrary.org/obo/CHEBI_59517 |
|
| has_alternative_id |
CHEBI:7456 |
|
| has_exact_synonym |
Nalidixic acid NALIDIXIC ACID 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid |
|
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
1,4-dihydro-1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid acidum nalidixicum 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid acido nalidixico nalidixic acid acide nalidixique 1-Aethyl-7-methyl-1,8-naphthyridin-4-on-3-karbonsaeure 1-ethyl-7-methyl-1,4-dihydro-1,8-naphthyridin-4-one-3-carboxylic acid 1-Ethyl-7-methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid 3-carboxy-1-ethyl-7-methyl-1,8-naphthyridin-4-one |
|
| id |
CHEBI:100147 |
|
| in_subset | ||
| inchi |
InChI=1S/C12H12N2O3/c1-3-14-6-9(12(16)17)10(15)8-5-4-7(2)13-11(8)14/h4-6H,3H2,1-2H3,(H,16,17) |
|
| inchikey |
MHWLWQUZZRMNGJ-UHFFFAOYSA-N |
|
| is conjugate acid of | ||
| label |
nalidixic acid |
|
| mass |
232.23530 |
|
| monoisotopicmass |
232.08479 |
|
| notation |
CHEBI:100147 |
|
| prefLabel |
nalidixic acid |
|
| smiles |
CCn1cc(C(O)=O)c(=O)c2ccc(C)nc12 |
|
| treeView |
http://purl.obolibrary.org/obo/CHEBI_73537 |
|
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_73537 |