loading...| Preferred Name |
|
|
| Synonyms |
MS Multiple Sclerosis, Acute Fulminating Sclerosis, Multiple MS (Multiple Sclerosis) Disseminated Sclerosis MULTIPLE SCLEROSIS ACUTE FULMINATING Sclerosis, Disseminated |
|
| Definitions |
An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903) |
|
| ID |
http://www.ebi.ac.uk/efo/EFO_0003885 |
|
| Obsolete |
true |
|
| database_cross_reference |
SNOMEDCT:24700007 MeSH:D009103 MedDRA:10028245 OMIM:612595 OMIM:614810 OMIM:126200 DOID:2377 ICD10:G35 ICD9:340 NCIt:C3243 |
|
| definition |
An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903) |
|
| deprecated |
true |
|
| has_exact_synonym |
Sclerosis, Disseminated MULTIPLE SCLEROSIS ACUTE FULMINATING Disseminated Sclerosis MS (Multiple Sclerosis) Sclerosis, Multiple Multiple Sclerosis, Acute Fulminating MS |
|
| label |
obsolete_multiple sclerosis |
|
| obsoleted_in_version |
3.38.0 |
|
| organizational_class |
true |
|
| prefixIRI |
efo1:EFO_0003885 |
|
| reason_for_obsolescence |
Replaced with Mondo term see https://github.com/ebispot/efo/issues/1381 |
|
| term editor |
Tomasz Adamusiak |
|
| term replaced by | ||
| subClassOf |