Cell Culture Ontology

Last uploaded: July 23, 2014
Preferred Name

Synonyms

Alzheimers

AD

Alzheimers Dementia

sporadic Alzheimer's disease

ALZHEIMER DIS

Alzheimer's

Presenile Alzheimer Dementia

[X]Dementia in Alzheimer's disease (disorder)

Alzheimer Dementia

Alzheimer Disease

Disease, Alzheimer's

Dementia in Alzheimer's disease

Dementia in Alzheimer's disease, unspecified (disorder)

ALZHEIMERS DIS

Alzheimer Type Dementia

Dementia, Presenile Alzheimer

Dementia, Presenile

Alzheimers disease

Dementia, Alzheimer Type

DAT - Dementia Alzheimer's type

Alzheimer's disease, NOS

AD - Alzheimer's disease

Dementia of the Alzheimer's type

[X]Dementia in Alzheimer's disease

Disease, Alzheimer

Alzheimer's disease (disorder)

Alzheimer's Dementia

Alzheimer Dementia, Presenile

Dementia in Alzheimer's disease (disorder)

Definitions

A progressive, neurodegenerative disease characterized by loss of function and death of nerve cells in several areas of the brain leading to loss of cognitive function such as memory and language. A dementia which is an incurable disease of unknown cause, starting in late middle age or in old age, that results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood, that leads in advanced cases to a profound decline in cognitive and physical functioning, and that is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid. A dementia that results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting in late middle age and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid. It is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability. A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)

ID

http://www.ebi.ac.uk/efo/EFO_0000249

Obsolete

true

database_cross_reference

MedDRA:10001896

OMIM:605526

NCIt:C34524

NIFSTD:birnlex_2092

OMIM:502500

OMIM:615590

OMIM:615711

SNOMEDCT:26929004

OMIM:104300

OMIM:608907

NCIt:C38778

SNOMEDCT:12348006

SNOMEDCT:15662003

MeSH:D000544

DOID:10652

ICD10:G30

ICD9:290.1

ICD9:331.0

NCIt:C2866

definition

A progressive, neurodegenerative disease characterized by loss of function and death of nerve cells in several areas of the brain leading to loss of cognitive function such as memory and language.

A dementia which is an incurable disease of unknown cause, starting in late middle age or in old age, that results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood, that leads in advanced cases to a profound decline in cognitive and physical functioning, and that is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.

A dementia that results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting in late middle age and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid. It is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability.

A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)

definition_citation

http://www.ncbi.nlm.nih.gov/pubmed/25687773

deprecated

true

has_exact_synonym

Dementia in Alzheimer's disease (disorder)

Alzheimer Dementia, Presenile

Alzheimer's Dementia

Alzheimer's disease (disorder)

Disease, Alzheimer

[X]Dementia in Alzheimer's disease

Dementia of the Alzheimer's type

AD - Alzheimer's disease

Alzheimer's disease, NOS

DAT - Dementia Alzheimer's type

Dementia, Alzheimer Type

Alzheimers disease

Dementia, Presenile

Dementia, Presenile Alzheimer

Alzheimer Type Dementia

ALZHEIMERS DIS

Dementia in Alzheimer's disease, unspecified (disorder)

Dementia in Alzheimer's disease

Disease, Alzheimer's

Alzheimer Disease

Alzheimer Dementia

[X]Dementia in Alzheimer's disease (disorder)

Presenile Alzheimer Dementia

Alzheimer's

ALZHEIMER DIS

sporadic Alzheimer's disease

Alzheimers Dementia

AD

Alzheimers

label

obsolete_Alzheimer's disease

obsoleted_in_version

3.38.0

organizational_class

true

prefixIRI

efo1:EFO_0000249

reason_for_obsolescence

Replaced with Mondo term see https://github.com/ebispot/efo/issues/1381

term editor

Tomasz Adamusiak

James Malone

term replaced by

http://purl.obolibrary.org/obo/MONDO_0004975

subClassOf

http://www.w3.org/2002/07/owl#Thing

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