loading...| Preferred Name |
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| Synonyms |
rac-(3S,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one Tetrabenazine 1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-2H-benzo(a)quinolizin-2-one Nitoman 1,2,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-2H-benzo[a]quinolizin-2-one tetrabenazine Ro 1-9569 tetrabenazinum TBZ Xenazine 2-oxo-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-benzoquinolizine tetrabenazina |
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| Definitions |
A racemate consisting of equal amounts of (3R,11bR)- and (3S,11bS)-9,10-dimethoxy-3-isobutyl-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one. An adrenergic uptake inhibitor, it was formerly used as an antipsychotic, but it is now used mainly for the treatment of various movement disorders including chorea, ballism, dystonias, and tardive dyskinesia. |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_9467 |
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| database_cross_reference |
SNOMEDCT:363581004 CiteXplore:20442355 CiteXplore:21487088 CiteXplore:20869622 KEGG COMPOUND:58-46-8 ChemIDplus:58-46-8 CiteXplore:10686169 Reaxys:9356999 CiteXplore:19929707 NIST Chemistry WebBook:58-46-8 CiteXplore:9040721 MeSH:D013747 NCIt:C81095 KEGG COMPOUND:C11168 KEGG DRUG:D08575 PMID:20442355 PMID:9040721 PMID:21487088 PMID:20869622 Patent:US2830993 PMID:19929707 KEGG:D08575 KEGG:C11168 Wikipedia:Tetrabenazine DrugBank:DB04844 CAS:58-46-8 PMID:10686169 |
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| definition |
A racemate consisting of equal amounts of (3R,11bR)- and (3S,11bS)-9,10-dimethoxy-3-isobutyl-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one. An adrenergic uptake inhibitor, it was formerly used as an antipsychotic, but it is now used mainly for the treatment of various movement disorders including chorea, ballism, dystonias, and tardive dyskinesia. |
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| has_exact_synonym |
rac-(3S,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one Tetrabenazine |
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| has_obo_namespace |
chebi_ontology |
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| has_related_synonym |
1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-2H-benzo(a)quinolizin-2-one Nitoman 1,2,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-2H-benzo[a]quinolizin-2-one tetrabenazine Ro 1-9569 tetrabenazinum TBZ Xenazine 2-oxo-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-benzoquinolizine tetrabenazina |
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| id |
CHEBI:9467 |
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| in_subset | ||
| label |
tetrabenazine |
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| notation |
CHEBI:9467 |
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| subClassOf |