Cell Culture Ontology

Last uploaded: July 23, 2014
Preferred Name

Synonyms

Salmeterol

(RS)-salmeterol

(+-)-4-hydroxy-alpha(1)-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-m-xylene-alpha,alpha(1)-diol

salmeterolum

(+-)-salmeterol

(RS)-4-hydroxy-alpha(1)-({[6-(4-phenylbutoxy)hexyl]amino}methyl)-1,3-benzenedimethanol

salmeterol

Definitions

A racemate consisting of equal parts of (R)- and (S)-salmeterol. It is a potent and selective beta2-adrenoceptor agonist (EC50 = 5.3 nM). Unlike other beta2 agonists, it binds to the exo-site domain of beta2 receptors, producing a slow onset of action and prolonged activation.

ID

http://purl.obolibrary.org/obo/CHEBI_9011

charge

0

database_cross_reference

NCIt:C29443

CiteXplore:22192967

CiteXplore:22245487

MeSH:C057823

SNOMEDCT:372515005

CiteXplore:22231554

KEGG COMPOUND:C07241

SNOMEDCT:108605008

ChemIDplus:89365-50-4

CiteXplore:22235841

KEGG COMPOUND:89365-50-4

KEGG DRUG:D05792

PMID:22231554

Wikipedia:Salmeterol

DrugBank:DB00938

PMID:22245487

HMDB:HMDB0015073

PMID:22235841

PMID:22192967

Patent:US4992474

KEGG:C07241

Patent:DE3414752

CAS:89365-50-4

KEGG:D05792

definition

A racemate consisting of equal parts of (R)- and (S)-salmeterol. It is a potent and selective beta2-adrenoceptor agonist (EC50 = 5.3 nM). Unlike other beta2 agonists, it binds to the exo-site domain of beta2 receptors, producing a slow onset of action and prolonged activation.

formula

C25H37NO4

has_exact_synonym

Salmeterol

has_obo_namespace

chebi_ontology

has_related_synonym

(RS)-salmeterol

(+-)-4-hydroxy-alpha(1)-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-m-xylene-alpha,alpha(1)-diol

salmeterolum

(+-)-salmeterol

(RS)-4-hydroxy-alpha(1)-({[6-(4-phenylbutoxy)hexyl]amino}methyl)-1,3-benzenedimethanol

salmeterol

has_role

http://www.ebi.ac.uk/efo/EFO_0001899

id

CHEBI:9011

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

label

salmeterol

mass

415.56560

monoisotopicmass

415.27226

notation

CHEBI:9011

subClassOf

http://purl.obolibrary.org/obo/CHEBI_24431

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