Cell Culture Ontology

Last uploaded: July 23, 2014
Preferred Name

Synonyms

Nimodipine

2-methoxyethyl propan-2-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

nimodipinum

2,6-dimethyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-beta-methoxyethyl ester 5-isopropyl ester

BAY e 9736

isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate

isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate

nimodipine

nimodipino

Periplum

Nimotop

Definitions

A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.

ID

http://purl.obolibrary.org/obo/CHEBI_7575

charge

0

database_cross_reference

KEGG DRUG:D00438

ChEMBL:465248

CiteXplore:17110283

KEGG COMPOUND:C07267

CiteXplore:8519001

CiteXplore:21869451

SNOMEDCT:87285001

CiteXplore:12137606

MeSH:D009553

Reaxys:459792

KEGG COMPOUND:66085-59-4

ChemIDplus:66085-59-4

CiteXplore:22300914

CiteXplore:22262041

NIST Chemistry WebBook:66085-59-4

SNOMEDCT:387502003

CiteXplore:16180362

NCIt:C692

LINCS:LSM-1659

PMID:8519001

PMID:22262041

PMID:17110283

KEGG:C07267

DrugBank:DB00393

Patent:US3799934

KEGG:D00438

Patent:DE2117571

PMID:21869451

Drug_Central:1937

PMID:22300914

CAS:66085-59-4

PMID:12137606

PMID:16180362

Wikipedia:Nimodipine

definition

A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.

formula

C21H26N2O7

has_exact_synonym

Nimodipine

2-methoxyethyl propan-2-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

has_obo_namespace

chebi_ontology

has_related_synonym

nimodipinum

2,6-dimethyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-beta-methoxyethyl ester 5-isopropyl ester

BAY e 9736

isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate

isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate

nimodipine

nimodipino

Periplum

Nimotop

has_role

http://purl.obolibrary.org/obo/CHEBI_35620

id

CHEBI:7575

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

inchi

InChI=1S/C21H26N2O7/c1-12(2)30-21(25)18-14(4)22-13(3)17(20(24)29-10-9-28-5)19(18)15-7-6-8-16(11-15)23(26)27/h6-8,11-12,19,22H,9-10H2,1-5H3

inchikey

UIAGMCDKSXEBJQ-UHFFFAOYSA-N

label

nimodipine

mass

418.44030

monoisotopicmass

418.17400

notation

CHEBI:7575

smiles

COCCOC(=O)C1=C(C)NC(C)=C(C1c1cccc(c1)[N+]([O-])=O)C(=O)OC(C)C

subClassOf

http://purl.obolibrary.org/obo/CHEBI_24532

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