Cell Culture Ontology

Last uploaded: July 23, 2014
Preferred Name

Synonyms

Cytarabine

4-amino-1-beta-D-arabinofuranosylpyrimidin-2(1H)-one

cytarabinum

Cytosine arabinoside

4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone

cytosine-beta-D-arabinofuranoside

ara-C

1-beta-D-Arabinofuranosylcytosine

citarabina

arabinocytosine

Cytosine-1-beta-D-arabinofuranoside

cytarabine

Arabinoside C

Definitions

A pyrimidine nucleoside in which cytosine is attached to D-arabinofuranose via a beta-N(1)-glycosidic bond. Used mainly in the treatment of leukaemia, especially acute non-lymphoblastic leukaemia, cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. It also has antiviral and immunosuppressant properties.

ID

http://purl.obolibrary.org/obo/CHEBI_28680

charge

0

database_cross_reference

SNOMEDCT:89265009

SNOMEDCT:387511003

MeSH:D003561

NCIt:C408

Beilstein:89175

Reaxys:89175

Drug_Central:770

HMDB:HMDB0015122

PDBeChem:AR3

DrugBank:DB00987

LINCS:LSM-5470

KEGG:C02961

KEGG:D00168

Wikipedia:Cytarabine

PMID:15492802

CAS:147-94-4

definition

A pyrimidine nucleoside in which cytosine is attached to D-arabinofuranose via a beta-N(1)-glycosidic bond. Used mainly in the treatment of leukaemia, especially acute non-lymphoblastic leukaemia, cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. It also has antiviral and immunosuppressant properties.

formula

C9H13N3O5

has_alternative_id

CHEBI:23532

CHEBI:40824

CHEBI:4074

has_exact_synonym

Cytarabine

4-amino-1-beta-D-arabinofuranosylpyrimidin-2(1H)-one

has_obo_namespace

chebi_ontology

has_related_synonym

cytarabinum

Cytosine arabinoside

4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone

cytosine-beta-D-arabinofuranoside

ara-C

1-beta-D-Arabinofuranosylcytosine

citarabina

arabinocytosine

Cytosine-1-beta-D-arabinofuranoside

cytarabine

Arabinoside C

has_role

http://www.ebi.ac.uk/efo/EFO_0001899

id

CHEBI:28680

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

inchi

InChI=1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7+,8-/m1/s1

inchikey

UHDGCWIWMRVCDJ-CCXZUQQUSA-N

label

cytarabine

mass

243.21674

monoisotopicmass

243.08552

notation

CHEBI:28680

smiles

Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)c(=O)n1

subClassOf

http://purl.obolibrary.org/obo/CHEBI_24532

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