Cell Culture Ontology

Last uploaded: July 23, 2014
Preferred Name

Synonyms

(1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol

Calcitriol

calcitriol

calcitriolum

(5Z,7E)-(1S,3R)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol

1alpha,25-dihydroxyvitamin D3

Decostriol

1alpha,25-dihydroxycholecalciferol

Rocaltrol

5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL

1alpha,25(OH)2D3

(1alpha,3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol

(1S,3R,5Z,7E)-9,10-secocholesta-5,7,10-triene-1,3,25-triol

1-alpha-25-Dihydroxyvitamin D3

Calcijex

1,25-DHCC

Definitions

A hydroxycalciol that is calcidiol in which the pro-S hydrogen of calcidiol is replaced by a hydroxy group. It is the active form of vitamin D3, produced fom calciol via hydoxylation in the liver to form calcidiol, which is subsequently oxidised in the kidney to give calcitriol.

ID

http://purl.obolibrary.org/obo/CHEBI_17823

charge

0

database_cross_reference

MeSH:D002117

NCIt:C330

CAS:32222-06-3

PDBeChem:VDX

KEGG:C01673

Wikipedia:Calcitriol

DrugBank:DB00136

Drug_Central:466

PMID:22905919

PMID:23103122

Reaxys:2227647

LIPID_MAPS_instance:LMST03020258

PMID:6687801

PMID:20599255

PMID:10217585

PMID:23144765

PMID:15928596

Beilstein:2227647

MetaCyc:CALCITRIOL

PMID:19429426

KEGG:D00129

definition

A hydroxycalciol that is calcidiol in which the pro-S hydrogen of calcidiol is replaced by a hydroxy group. It is the active form of vitamin D3, produced fom calciol via hydoxylation in the liver to form calcidiol, which is subsequently oxidised in the kidney to give calcitriol.

formula

C27H44O3

has_alternative_id

CHEBI:13932

CHEBI:46435

CHEBI:3307

CHEBI:19209

has_exact_synonym

(1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol

Calcitriol

calcitriol

has_obo_namespace

chebi_ontology

has_related_synonym

calcitriolum

(5Z,7E)-(1S,3R)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol

1alpha,25-dihydroxyvitamin D3

Decostriol

1alpha,25-dihydroxycholecalciferol

Rocaltrol

5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL

1alpha,25(OH)2D3

(1alpha,3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol

(1S,3R,5Z,7E)-9,10-secocholesta-5,7,10-triene-1,3,25-triol

1-alpha-25-Dihydroxyvitamin D3

calcitriol

Calcijex

1,25-DHCC

has_role

http://purl.obolibrary.org/obo/CHEBI_33229

id

CHEBI:17823

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

inchi

InChI=1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10+,21-11-/t18-,22-,23-,24+,25+,27-/m1/s1

inchikey

GMRQFYUYWCNGIN-NKMMMXOESA-N

label

calcitriol

mass

416.63646

monoisotopicmass

416.32905

notation

CHEBI:17823

smiles

[H][C@@]1(CC[C@@]2([H])\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C)[C@H](C)CCCC(C)(C)O

subClassOf

http://purl.obolibrary.org/obo/CHEBI_27300

Delete Subject Author Type Created
No notes to display
Create mapping

Delete Mapping To Ontology Source
There are currently no mappings for this class.